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Mr
Pauline Mwinzi

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Project Title

Immune reconstitution inflammatory syndrome (IRIS) in schistosomiasis patients undergoing HAART

EDCTP Project

TA.2008.40200.007

EDCTP Program

EDCTP1

EDCTP Project Call

Senior Fellowship (SF)

Project Objectives

To study the Immunopathogenesls, clinical aspects and management of manifestation of IRIS in HIV-schistosome co-infection patients undergoing HAART In western Kenya. Schistosome infections are common in the same areas where HIV prevalence is also high.

Study Design

Prevalence study on IRIS in schistomiasis on HAART

Host Organisation

Department Institution Country
Kenya Medical Research Institute (KEMRI) Kenya

Results & Outcomes

622 HIV-positive patients were followed. In the first year of follow up 12 patients expressed signs and symptoms of IRIS of whom two met the case definition of IRIS. As a requirement for all staff participants on this project, GCP/GCLP training was provided online from the EDCTPsponsored AMANET online courses.