A pilot study of the Implementation of Seasonal Intermittent Preventive Treatment with Community Participation in Senegal
The purpose of this trial was to compare the acceptability, efficacy and safety of three alternative drug regimens for use for seasonal Intermittent Preventive Treatment to prevent malaria in children. Children aged 2 months to 5 years were randomized to receive IPT with one of three regimens during the transmission season: sulfadoxinepyrimethamine (SP) plus amodiaquine, show to be highly effective for IPT in a recent trial; SP plus piperaquine, used for malaria prophylaxis in China for many years; or Duocotexcin (a combination of piperaquine with an artemisinin).
Department | Institution | Country |
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University Cheikh Anta Diop | Senegal |
TA.2005.40200.004
EDCTP1
Senior Fellowship (SF)
Phase III Clinical Trial