Back to fellows
Profile Background
profile

Associate Professor
Kwadwo Asamoah Kusi

Related fellows

Dr Moses Egesa

Dr Ndong Ignatius Cheng

EDCTP Career Development Fellow

View
Dr Moses Egesa

Dr Francis Ndungu

Group Leader

View
Dr Moses Egesa

Professor Daniel Dodoo

Associate Professor

View
Show more
Profile EDCTP Fellowship 1

Current Organisation

NOGUCHI MEMORIAL INSTITUTE FOR MEDICAL RESEARCH(NM

Current Job Title

Senior Research Fellow

Biography

Publications

Authors:
Kwadwo Asamoah Kusi Augustina Frimpong Frederica Dedo Partey Helena Lamptey Linda Eva Amoah Michael Fokuo Ofori

Journal:
AAS Open Research

Content:

Date:
2021-06-07

Authors:
Frimpong, A. Amponsah, J. Adjokatseh, A.S. Agyemang, D. Bentum-Ennin, L. Ofori, E.A. Kyei-Baafour, E. Akyea-Mensah, K. Adu, B. Mensah, G.I. Amoah, L.E. Kusi, K.A.

Journal:
Frontiers in Microbiology

Content:

Date:
2021-01-01

Authors:
Harini Ganeshan Kwadwo A. Kusi Dorothy Anum Michael R. Hollingdale Bjoern Peters Yohan Kim John K. A. Tetteh Michael F. Ofori Ben A. Gyan Kwadwo A. Koram Jun Huang Maria Belmonte Jo Glenna Banania Daniel Dodoo Eileen Villasante Martha Sedegah

Journal:
Malaria Journal

Content:

Date:
2016-12-01

Authors:
Gyan B Goka BQ Adjei GO Tetteh JK Kusi KA Aikins A Dodoo D Lesser ML Sison CP Das S Howard ME Milbank E Fischer K Rafii S Jin D Golightly LM

Journal:

Content:

Date:
2009-04-01

Authors:
Amlabu, E. Nyarko, P.B. Opoku, G. Ibrahim-Dey, D. Ilani, P. Mensah-Brown, H. Akporh, G.A. Akuh, O.-A. Ayugane, E.A. Amoh-Boateng, D. Kusi, K.A. Awandare, G.A.

Journal:
Experimental Biology and Medicine

Content:

Date:
2021-01-01

Authors:
Lamptey H Ofori MF Adu B Kusi KA Dickson EK Quakyi I Alifrangis M

Journal:
BMC research notes

Content:

Date:
2019-03-01

Authors:
Kusi KA Faber BW Koopman G Remarque EJ

Journal:
Expert review of vaccines

Content:

Date:
2018-01-01

Authors:
Kwadwo A. Kusi Adrian J.F. Luty Felix E. Aggor Linda E. Amoah Dorothy Anum Yvonne Nartey Daniel Amoako-Sakyi Dorcas Obiri-Yeboah Michael Hollingdale Harini Ganeshan Maria Belmonte Bjoern Peters Yohan Kim John Tetteh Eric Kyei-Baafour Daniel Dodoo Eileen Villasante Martha Sedegah

Journal:
PLOS ONE

Content:

Date:
2020-02-10

Authors:

Journal:
Parasites & Vectors

Content:

Date:
2017-06-27

Authors:
Kwadwo A. Kusi Érika Martins Braga Emmanuel A. Manu Theresa Manful Gwira Eric Kyei-Baafour Emmanuel K. Dickson Jones A. Amponsah Edmond J. Remarque Bart W. Faber Clemens H. M. Kocken Daniel Dodoo Ben A. Gyan Gordon A. Awandare Frank Atuguba Abraham R. Oduro Kwadwo A. Koram

Journal:
PLOS ONE

Content:

Date:
2017-09-25

Authors:
Kwadwo Kusi

Journal:
protocols.io

Content:

Date:
2017-08-01

Authors:
Henry Asare-Anane Collins Paa Kwesi Botchey Emmanuel Kwaku Ofori Isaac Boamah Sandra Crabbe Kwadwo Asamoah-Kusi

Journal:
SAGE Open Medicine

Content:

Date:
2018-01-01

Authors:

Journal:
Journal of Infectious Diseases

Content:

Cerebral malaria (CM) may cause death or long-term neurological
damage in children, and several host genetic risk factors
have been reported. Malaria-specific immunoglobulin (Ig) G3
antibodies are crucial to human immune response against malaria.
The hinge region of IgG3 exhibits length polymorphism
(with long [L], medium [M], and short [S] alleles), which may
influence its functionality. We studied IgG3 hinge region length
polymorphisms in 136 Ghanaian children with malaria. Using
logistic regression models, we found that children with the
recessive MM allotype encoding medium IgG3 hinge region
length had an increased risk of CM (adjusted odds ratio, 6.67
[95% confidence interval, 1.30–34.32]; P = .004) . This has implications
for future epidemiological studies on CM.

Date:
2021-11-10

Authors:
Kusi KA Faber BW van der Eijk M Thomas AW Kocken CH Remarque EJ

Journal:

Content:

Date:
2011-01-01

Authors:
Thiam LG Aniweh Y Quansah EB Donkor JK Gwira TM Kusi KA Niang M Awandare GA

Journal:
Experimental biology and medicine (Maywood, N.J.)

Content:

Date:
2020-01-01

Authors:
Adukpo S Kusi KA Ofori MF Tetteh JK Amoako-Sakyi D Goka BQ Adjei GO Edoh DA Akanmori BD Gyan BA Dodoo D

Journal:

Content:

Date:
2013-01-01

Authors:
Thiam, L.G. Nyarko, P.B. Kusi, K.A. Niang, M. Aniweh, Y. Awandare, G.A.

Journal:
Scientific Reports

Content:

Date:
2021-01-01

Authors:
Stephen Osei-Wusu Frederick Quinn Isaac Darko Otchere Portia Morgan Abdul Basit Musah Ishaque Mintah Siam Diana Asandem Theophilus Afum Prince Asare Adwoa Asante-Poku Kwadwo Asamoah Kusi Sebastien Gagneux Dorothy Yeboah-Manu

Journal:
PLOS ONE

Content:

Date:
2021-08-26

Authors:
Bernard Tornyigah Romain Coppée Pascal Houze Kwadwo A. Kusi Bright Adu Isabella Quakyi Nathaniel Coleman Atikatou Mama Philippe Deloron Abraham K. Anang Jérôme Clain Rachida Tahar Michael F. Ofori Nicaise Tuikue Ndam

Journal:
Antimicrobial Agents and Chemotherapy

Content:

Date:
2020-05-21

Authors:
Courtin D Oesterholt M Huismans H Kusi K Milet J Badaut C Gaye O Roeffen W Remarque EJ Sauerwein R Garcia A Luty AJ

Journal:

Content:

Date:
2009-01-01

Authors:

Journal:
Malaria Journal

Content:

Date:
2017-04-11

Authors:
Dodoo D Aikins A Kusi KA Lamptey H Remarque E Milligan P Bosomprah S Chilengi R Osei YD Akanmori BD Theisen M

Journal:

Content:

Date:
2008-01-01

Authors:
Ayertey, F. Ofori-Attah, E. Antwi, S. Amoa-Bosompem, M. Djameh, G. Lartey, N.L. Ohashi, M. Kusi, K.A. Appiah, A.A. Appiah-Opong, R. Okine, L.K.

Journal:
Journal of Traditional and Complementary Medicine

Content:

Date:
2021-01-01

Authors:
Kusi KA Dodoo D Bosomprah S van der Eijk M Faber BW Kocken CH Remarque EJ

Journal:

Content:

Date:
2012-01-01

Authors:
Lamptey, H. Ofori, M.F. Kusi, K.A. Adu, B. Owusu-Yeboa, E. Kyei-Baafour, E. Arku, A.T. Bosomprah, S. Alifrangis, M. Quakyi, I.A.

Journal:
Malaria Journal

Content:

Date:
2018-01-01

Authors:
Olsen RW Ecklu-Mensah G Bengtsson A Ofori MF Kusi KA Koram KA Hviid L Adams Y Jensen ATR

Journal:
Infection and immunity

Content:

Date:
2019-09-01

Authors:
Gyan, B. Goka, B.Q. Adjei, G.O. Tetteh, J.K.A. Kusi, K.A. Aikins, A. Dodoo, D. Lesser, M.L. Sison, C.P. Das, S. Howard, M.E. Milbank, E. Fischer, K. Rafii, S. Jin, D. Golightly, L.M.

Journal:
American Journal of Tropical Medicine and Hygiene

Content:

Date:
2009-01-01

Authors:
Kusi, K.A. Ofori, E.A. Akyea-Mensah, K. Kyei-Baafour, E. Frimpong, A. Ennuson, N.A. Belmonte, M. Ganeshan, H. Huang, J. Amoah, L.E. Villasante, E. Sedegah, M.

Journal:
Vaccine

Content:

Date:
2022-01-01

Authors:
Kusi KA Bosomprah S Dodoo D Kyei-Baafour E Dickson EK Mensah D Angov E Dutta S Sedegah M Koram KA

Journal:

Content:

Date:
2014-01-01

Authors:
Frimpong, A. Amponsah, J. Agyemang, D. Adjokatseh, A.S. Eyiah-Ampah, S. Ennuson, N.A. Obiri, D. Amoah, L.E. Kusi, K.A.

Journal:
Open Forum Infectious Diseases

Content:

Date:
2021-01-01

Authors:
Dídac Macià Joseph J. Campo Gemma Moncunill Chenjerai Jairoce Augusto J. Nhabomba Maximilian Mpina Hermann Sorgho David Dosoo Ousmane Traore Kwadwo A. Kusi Nana Aba Williams Amit Oberai Arlo Randall Hector Sanz Clarissa Valim Kwaku P. Asante Seth Owusu-Agyei Halidou Tinto Selidji T. Agnandji Simon Kariuki Ben Gyan Claudia Daubenberger Benjamin Mordmüller Paula Petrone Carlota Dobaño

Journal:
JCI Insight

Content:

Date:
2022-04-21

Authors:
Omarine Nfor Nlinwe Kwadwo Asamoah Kusi Bright Adu Martha Sedegah

Journal:
Vaccine

Content:

Date:
2018-04-01

Authors:
Godfrey Bwire Alex Riolexus Ario Patricia Eyu Felix Ocom Joseph F. Wamala Kwadwo A. Kusi Latif Ndeketa Kondwani C. Jambo Rhoda K. Wanyenze Ambrose O. Talisuna

Journal:
BMC Medicine

Content:

Date:
2022-12-01

Authors:

Journal:

Content:

Date:
2016-04-07

Authors:
Domfeh, S.A. Narkwa, P.W. Quaye, O. Kusi, K.A. Rivera, O. Danaah, M.M. Musah, B.A.N. Awandare, G.A. Mensah, K.B. Mutocheluh, M.

Journal:
Scientific African

Content:

Date:
2021-01-01

Authors:
Omarine N. Nlinwe Luzia Helena Carvalho Ebenezer A. Ofori Kwadwo Akyea-Mensah Eric Kyei-Baafour Harini Ganeshan Maria Belmonte Bjoern Peters Eileen Villasante Martha Sedegah Kwadwo Asamoah Kusi

Journal:
PLOS ONE

Content:

Date:
2021-09-10

Authors:
Amoah, L.E. Abagna, H.B. Akyea-Mensah, K. Lo, A.C. Kusi, K.A. Gyan, B.A.

Journal:
BMC immunology

Content:

Date:
2018-01-01

Authors:
Ebenezer A. Ofori John K. A. Tetteh Augustina Frimpong Harini Ganeshan Maria Belmonte Bjoern Peters Eileen Villasante Martha Sedegah Michael F. Ofori Kwadwo A. Kusi

Journal:
Malaria Journal

Content:

Date:
2021-12-01

Authors:
Kwadwo Asamoah Kusi Joao Aguiar Selassie Kumordjie Felix Aggor Jessica Bolton Andrea Renner Eric Kyei-Baafour Naiki Puplampu Maria Belmonte Daniel Dodoo Ben Adu Gyan Michael Fokuo Ofori Abraham Rex Oduro Frank Atuguba Kwadwo Ansah Koram Nehkonti Adams Andrew Letizia Eileen Villasante Martha Sedegah

Journal:
Scientific Reports

Content:

Date:
2019-12-01

Authors:
Mama, A. Ahiabor, C. Tornyigah, B. Frempong, N.A. Kusi, K.A. Adu, B. Courtin, D. Houzé, S. Deloron, P. Ofori, M.F. Anang, A.K. Ariey, F. Ndam, N.T.

Journal:
Malaria Journal

Content:

Date:
2022-01-01

Authors:
Ebenezer Addo Ofori John Kweku A Tetteh Augustina Frimpong Harini Ganeshan Maria Belmonte Bjoern Peters Eileen Villasante Martha Sedegah Michael Fokuo Ofori Kwadwo Asamoah Kusi

Journal:

Content:

Date:
2021-07-02

Authors:
Frimpong, A. Amponsah, J. Adjokatseh, A.S. Agyemang, D. Bentum-Ennin, L. Ofori, E.A. Kyei-Baafour, E. Akyea-Mensah, K. Adu, B. Mensah, G.I. Amoah, L.E. Kusi, K.A.

Journal:
Frontiers in Microbiology

Content:

Date:
2020-01-01

Authors:
Anum D Kusi KA Ganeshan H Hollingdale MR Ofori MF Koram KA Gyan BA Adu-Amankwah S Badji E Huang J Belmonte M Banania GJ Kwofie TB Villasante E Dodoo D Sedegah M

Journal:

Content:

Date:
2015-01-01

Authors:
Kwadwo A Kusi

Journal:
Vaccine

Content:

Sterile protection against clinical malaria has been achieved in animal models and experimental
human challenge studies involving immunization with radiation attenuated Plasmodium falciparum
sporozoite vaccines as well as by live sporozoites under chloroquine prophylaxis. Parasite-specific
IFN-c and granzyme B-secreting CD8 + T cells have been identified as key mediators of protection.
Although the exact parasite targets of protective CD8 + T cell responses are not fully defined,
responses against a handful of vaccine candidate antigens have been associated with protection.
Identifying the T cell targets in these antigens will facilitate the development of simpler, costeffective,
and efficacious next generation multi-epitope vaccines. The aim of this study was to identify
immunodominant portions of four malaria vaccine candidate antigens using peripheral blood
mononuclear cells (PBMCs) from adults with life-long exposure to malaria parasites. Cryopreserved
PBMCs from 291 HLA-typed subjects were stimulated with pools of overlapping 15mer peptides spanning
the entire sequences of P. falciparum circumsporozoite protein (CSP, 9 pools), apical membrane
antigen 1 (AMA1, 12 pools), thrombospondin related anonymous protein (TRAP, 6 pools) and cell
traversal for ookinetes and sporozoites (CelTOS, 4 pools) in FluoroSpot assays. 125 of 291 subjects
made IFN-c responses to 30 of the 31 peptide pools tested and 22 of 291 made granzyme B
responses, with 20 making dual responses. The most frequent responses were to the CSP Cterminal
region and the least frequent responses were to TRAP and CelTOS. There was no association
between FluoroSpot responses and active malaria infection, detected by either microscopy, RDT, or
PCR.
In conclusion, CSP and AMA1 have relatively higher numbers of epitopes that trigger IFN-c and
granzyme B-secreting T cells in adults with life-long malaria parasite exposure compared to the other
two antigens tested, and highlights the continued relevance of these two antigens as vaccine
candidates.

Date:
2021-12-27

Authors:
Kwadwo Asamoah Kusi Augustina Frimpong Frederica Dedo Partey Helena Lamptey Linda Eva Amoah Michael Fokuo Ofori

Journal:

Content:

Date:
2021-10-18

Authors:
Kyei-Baafour E Tornyigah B Buade B Bimi L Oduro AR Koram KA Gyan BA Kusi KA

Journal:
Journal of tropical medicine

Content:

Date:
2020-03-01

Authors:
Laty G. Thiam Prince B. Nyarko Kwadwo A. Kusi Makhtar Niang Yaw Aniweh Gordon A. Awandare

Journal:

Content:

Date:
2020-05-27

Authors:

Journal:
Frontiers in Immunology

Content:

Date:
2019-06-18

Authors:
Isabella Quakyi Bernard Tornyigah Pascal Houze Kwadwo A. Kusi Nathaniel Coleman Guillaume Escriou Amos Laar Michel Cot Julius Fobil Gloria Quansah Asare Philippe Deloron Abraham K. Anang Gilles Cottrell Michael F. Ofori Nicaise Tuikue Ndam

Journal:
Scientific Reports

Content:

Date:
2019-12-01

Authors:
Kwadwo A. Kusi Georges Snounou Samuel Bosomprah Eric Kyei-Baafour Emmanuel K. Dickson Bernard Tornyigah Evelina Angov Sheetij Dutta Daniel Dodoo Martha Sedegah Kwadwo A. Koram

Journal:
PLOS ONE

Content:

Date:
2016-11-22

Authors:
Kusi KA Faber BW Thomas AW Remarque EJ

Journal:

Content:

Date:
2009-01-01

Authors:
Kusi KA Remarque EJ Riasat V Walraven V Thomas AW Faber BW Kocken CH

Journal:

Content:

Date:
2011-01-01

Authors:
Frimpong, A. Kusi, K.A. Tornyigah, B. Ofori, M.F. Ndifon, W.

Journal:
Malaria Journal

Content:

Date:
2018-01-01

Authors:

Journal:

Content:

Date:
2015-01-01

Authors:
Aniweh Y Suurbaar J Morang'a CM Nyarko PB Wright KE Kusi KA Ansah F Kyei-Baafour E Quansah E Asante J Thiam LG Higgins MK Awandare GA

Journal:
Scientific reports

Content:

Date:
2020-01-01

Authors:
Augustina Frimpong Kwadwo Asamoah Kusi Michael Fokuo Ofori Wilfred Ndifon

Journal:
Frontiers in Immunology

Content:

Date:
2018-11-01

Authors:
Domfeh, S.A. Narkwa, P.W. Quaye, O. Kusi, K.A. Awandare, G.A. Ansah, C. Salam, A. Mutocheluh, M.

Journal:
BMC Complementary Medicine and Therapies

Content:

Date:
2021-01-01

Authors:
Obiri, D. Erskine, I.J. Oduro, D. Kusi, K.A. Amponsah, J. Gyan, B.A. Adu-Bonsaffoh, K. Ofori, M.F.

Journal:
Scientific Reports

Content:

Date:
2020-01-01

Authors:
Kusi KA Faber BW Riasat V Thomas AW Kocken CH Remarque EJ

Journal:

Content:

Date:
2010-01-01

Authors:
Kwadwo Asamoah Kusi Augustina Frimpong Frederica Dedo Partey Helena Lamptey Linda Eva Amoah Michael Fokuo Ofori

Journal:
AAS Open Research

Content:

Date:
2021-01-13

Authors:
Tandoh KZ Kusi KA Archampong TN Boamah I Quaye O

Journal:
Experimental biology and medicine (Maywood, N.J.)

Content:

Date:
2020-04-01

Authors:
Amoah LE Kakaney C Kwansa-Bentum B Kusi KA

Journal:

Content:

Date:
2015-01-01

Authors:
Kusi KA Gyan BA Goka BQ Dodoo D Obeng-Adjei G Troye-Blomberg M Akanmori BD Adjimani JP

Journal:

Content:

Date:
2008-09-01

Authors:
Eric Kyei-Baafour Takafumi Tsuboi Mavis Oppong Kwadwo Asamoah Kusi Abena Fremaah Frempong Belinda Aculley Fareed K. N. Arthur Regis Wendpayangde Tiendrebeogo Susheel K. Singh Michael Theisen Margaret Kweku Bright Adu Lars Hviid Michael Fokuo Ofori

Journal:
PLOS ONE

Content:

Date:
2021-04-22