The EDCTP Alumni Network

Dr
Gerald Mboowa

Related fellows

Professor Andre Pascal Kengne

Director, Non-Communicable Diseases Research Unit

View

Dr Obinna Ekwunife

Senior Lecturer

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Dr Zivai Nenguke

Project Director

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Profile EDCTP Fellowship 1

Project Title

Pathogen detection in HIV-infected children and adolescents with non-malarial febrile illnesses using metagenomic next-generation sequencing approach in Uganda

EDCTP Project

TMA2020CDF-3159

EDCTP Program

EDCTP2

EDCTP Project Call

Career Development Fellowship (CDF)

Host Organisation

Department	Institution	Country

Current Organisation

INFECTIOUS DISEASES INSTITUTE

Current Job Title

Scientist

Biography

Publications

Authors:

Journal:

Immunogenetics

Content:

In modern medicine, vaccination is one of the most effective public health strategies to prevent infectious diseases. Indisput- ably, vaccines have saved millions of lives by reducing the burden of many serious infections such as polio, tuberculosis, measles, pneumonia, and tetanus. Despite the recent recommendation by the World Health Organization (WHO) to roll out RTS,S/AS01, this malaria vaccine still faces major challenges of variability in its efficacy partly due to high genetic variation in humans and malaria parasites. Immune responses to malaria vary between individuals and populations. Human genetic variation in immune system genes is the probable cause for this heterogeneity. In this review, we will focus on human genetic factors that determine variable responses to vaccination and how variation in immune system genes affect the immunogenic- ity and efficacy of the RTS,S/AS01 vaccine.

Date:

2023-04-21

Dr Gerald Mboowa

Related fellows

Professor Andre Pascal Kengne

Dr Obinna Ekwunife

Dr Zivai Nenguke

Project Title

EDCTP Project

EDCTP Program

EDCTP Project Call

Host Organisation

Current Organisation

Current Job Title

Biography

Publications

Dr
Gerald Mboowa