The EDCTP Alumni Network

Department	Institution	Country
Non-Communicable Diseases Research Unit	South African Medical Research Council	South Africa

Authors:

Kengne AP Libend CN Dzudie A Menanga A Dehayem MY Kingue S Sobngwi E

Journal:

The Pan African medical journal

Content:

Date:

2014-10-01

Authors:

Pheiffer C Erasmus RT Kengne AP Matsha TE

Journal:

Clinical biochemistry

Content:

Date:

2015-12-01

Authors:

Yako YY Madubedube JH Kengne AP Erasmus RT Pillay TS Matsha TE

Journal:

African health sciences

Content:

Date:

2015-12-01

Authors:

Kufe NC Masemola M Chikowore T Kengne AP Olsson T Goedecke JH Micklesfield LK

Journal:

BMJ open

Content:

Date:

2019-01-01

Authors:

GACD Hypertension Research Programme Writing Group Peiris D Thompson SR Beratarrechea A Cárdenas MK Diez-Canseco F Goudge J Gyamfi J Hypertension Research Programme members

Journal:

Implementation science : IS

Content:

Date:

2015-11-01

Authors:

Cindy George Tandi E Matsha Saarah FG Davids Gloudina M Hon U Chikte Rajiv T Erasmus Andre P Kengne

Journal:

South African Dental Journal

Content:

Date:

2022-03-08

Authors:

Kaze FF Ashuntantang G Kengne AP Hassan A Halle MP Muna W

Journal:

Hemodialysis international. International Symposium on Home Hemodialysis

Content:

Date:

2012-04-01

Authors:

Nouya AY Nansseu JR Moor VJ Pieme CA Noubiap JJ Tchoula CM Mokette BM Takam RD Tankeu F Ngogang JY Kengne AP

Journal:

Diabetes research and clinical practice

Content:

Date:

2014-10-01

Authors:

Kengne AP Dzudie A Dongmo L

Journal:

Neuroepidemiology

Content:

Date:

2006-10-01

Authors:

Mazidi M Heidari-Bakavoli A Khayyatzadeh SS Azarpazhooh MR Nematy M Safarian M Esmaeili H Parizadeh SM Ghayour-Mobarhan M Kengne AP Ferns GA

Journal:

European journal of clinical nutrition

Content:

Date:

2016-09-01

Authors:

Werfalli M Raubenheimer PJ Engel M Musekiwa A Bobrow K Peer N Hoegfeldt C Kalula S Kengne AP Levitt NS

Journal:

Systematic reviews

Content:

Date:

2020-06-01

Authors:

Andre Pascal Kengne Eugene Sobngwi Leopold Fezeu Paschal Kum Awah Sylvestre Dongmo

Journal:

Content:

Setting-up nurse-led pilot clinics for the management of non-communicable diseases at primary health care level in resource-limited settings of Africa

Date:

Authors:

Nong-Libend C Menanga AP Kengne AP Dehayem M Sobngwi E Kingue S

Journal:

Diabetes & metabolism

Content:

Date:

2012-05-01

Authors:

Echouffo-Tcheugui JB Kengne AP Ali MK

Journal:

Current diabetes reports

Content:

Date:

2018-09-01

Authors:

Kaze FF Meto DT Halle MP Ngogang J Kengne AP

Journal:

BMC nephrology

Content:

Date:

2015-07-01

Authors:

Theodosia Adom Anniza De Villiers Thandi Puoane André Pascal Kengne

Journal:

Content:

Abstract Background There is limited data on risk factors associated with childhood overweight and obesity in Ghanaian school children. Therefore, the aim of this study was to assess the prevalence of overweight and obesity and associated risk factors in Ghanaian school children. Methods Data for this study were obtained from a cross-sectional survey of 543 children aged 8 and 11 years, attending private and public primary schools in the Adentan Municipality of Greater Accra Region, Ghana. Anthropometric, dietary, physical activity, sedentary behaviours, sleep duration and socio-demographic data were collected. BMI-for-age Z-scores were used to classify children as overweight/obesity. Multivariable logistic regressions were used to assess the determinants of overweight and obesity. Results The overall prevalence of overweight/obesity was 16.4%. Children living in middle (OR = 1.88; 95% CI = 1.01–3.50) and high socioeconomic status (SES) households (2.58; 1.41–4.70) had increased odds of being overweight or obese compared to those living in low SES household. Attending private school (2.44; 1.39–4.29) and watching television for more than 2 h each day (1.72; 1.05–2.82) were significantly associated with increased likelihood of overweight and obesity. Children who slept for more than 9 h a night (0.53; 0.31–0.88) and walked or cycled to school (0.51; 0.31–0.82) had lower odds of being overweight or obese. Conclusions A number of modifiable risk factors were associated with overweight and obesity in this study. Public health strategies to prevent childhood obesity should target reduction in television watching time, promoting active transport to and from school, and increasing sleep duration.

Date:

2019-01-01

Authors:

Mbanya V Hussain A Kengne AP

Journal:

Primary care diabetes

Content:

Date:

2015-05-01

Authors:

Pule GD Ngo Bitoungui VJ Chetcha Chemegni B Kengne AP Wonkam A

Journal:

Hemoglobin

Content:

Date:

2016-11-01

Authors:

Feigin VL Krishnamurthi RV Parmar P Norrving B Mensah GA Bennett DA Barker-Collo S Moran AE Sacco RL Truelsen T Davis S Pandian JD GBD 2013 Stroke Panel Experts Group

Journal:

Neuroepidemiology

Content:

Date:

2015-10-01

Authors:

Kengne AP Sobngwi E Echouffo-Tcheugui JB Mbanya JC

Journal:

Heart (British Cardiac Society)

Content:

Date:

2013-05-01

Authors:

Mazidi M Kengne AP Sahebkar A Banach M

Journal:

Angiology

Content:

Date:

2017-06-01

Authors:

Journal:

International journal of epidemiology

Content:

BACKGROUND: As the relation between socioeconomic status (SES) and obesity may depend on the stage of development of a country, this relation is assessed in adults from urban Cameroon. METHODS: A sample comprising 1530 women and 1301 men aged 25 years and above, from 1897 households in the Biyem-Assi health area in the capital of Cameroon, Yaoundé, were interviewed about their household amenities, occupation, and education. Weight, height, and waist circumference were measured and subjects were classified as obese if their BMI>or=30 kg/m2 or overweight if BMI was between 25.0 and 29.9 kg/m2. Abdominal obesity was defined by a waist circumference>or=80 cm in women and>or=94 cm in men. RESULTS: Of the sample studied 33% of women and 30% of men were overweight (P<0.08), whereas 22% of women and 7% of men were obese (P<0.001). Abdominal obesity was present in 67% of women and 18% of men (P<0.001). After adjusting for age, leisure time physical activity, alcohol consumption, and tobacco smoking, the prevalence of overweight+obesity, obesity, and abdominal obesity increased with quartiles of household amenities in both genders and with occupational level in men. CONCLUSION: SES is positively associated with adiposity in urban Cameroon after adjusting for confounding factors.

Date:

2005-10-28

Authors:

Marie Patrice Halle Gloria Ashuntantang Francois Folefack Kaze Christian Takongue Andre-Pascal Kengne

Journal:

BMC Nephrology

Content:

Date:

2016-12-01

Authors:

GBD 2017 Oesophageal Cancer Collaborators

Journal:

The lancet. Gastroenterology & hepatology

Content:

Date:

2020-04-01

Authors:

Boateng D Agyemang C Beune E Meeks K Smeeth L Schulze M Addo J de-Graft Aikins A Galbete C Bahendeka S Danquah I Agyei-Baffour P Klipstein-Grobusch K

Journal:

Circulation. Cardiovascular quality and outcomes

Content:

Date:

2017-11-01

Authors:

Matsha TE Hartnick MD Kisten Y Eramus RT Kengne AP

Journal:

Journal of diabetes

Content:

Date:

2013-10-01

Authors:

Mazidi M Kengne AP George ES Siervo M

Journal:

The British journal of nutrition

Content:

Date:

2019-08-01

Authors:

Katte JC Dzudie A Sobngwi E Mbong EN Fetse GT Kouam CK Kengne AP

Journal:

BMC public health

Content:

Date:

2014-07-01

Authors:

Alain Lekoubou Clovis Nkoke Anastase Dudzie Andre Pascal Kengne

Journal:

Content:

Background: Despite the increasing availability of head computerized tomography (CT) in resource-limited settings, it is unclear if brain-imaging-based diagnosis of stroke affects the outcomes in the absence of dedicated structures for acute stroke management. Objectives: In a major referral hospital in the capital city of Cameroon, we compared in-hospital mortality rates in patients with a WHO-based diagnosis of stroke between participants with and without brain imaging on admission. Methods: Stroke patients with and without admission brain imaging were compared for demographic characteristics, risk factors, clinical and laboratory characteristic, and in-hospital mortality. Heterogeneities in mortality rates (CT vs. No CT) across major subgroups were investigated via interaction tests, and logistic regressions used to adjust for extraneous factors such as age, sex, year of study, residency, history of diabetes and hypertension, history of stroke, Glasgow coma scale, and delay between stroke symptoms onset and hospital admission. Results: Of the 1688 participants included in the final analysis, 1048 (62.1%) had brain imaging. The median age of the non-CT vs. CT groups was 65 vs. 62 years (p-value < 0.0001%). The death rate of non-CT vs. CT groups was 27.5% vs. 16.4% (p < 0.0001). This difference was mostly similar across major subgroups, and robust to the adjustments for confounders (in spite of substantial attenuation), with excess deaths in those with CT ranging from 65% to 149%. Conclusion: In this resource-limited environment, the absence of brain imaging on admission was associated with high in-hospital death from stroke, which was only partially explained by delayed hospitalization with severe disease. These results stressed the importance of scaling up acute stroke management in low- and middle-income countries.

Date:

2016-01-01

Authors:

Pefura Yone EW Kuaban C Kengne AP

Journal:

BMC infectious diseases

Content:

Date:

2012-08-01

Authors:

Zemlin AE Matsha TE Kengne AP Hon GM Erasmus RT

Journal:

Annals of clinical biochemistry

Content:

Date:

2016-09-01

Authors:

Engel ME Cohen K Gounden R Kengne AP Barth DD Whitelaw AC Francis V Badri M Stewart A Dale JB Mayosi BM Maartens G

Journal:

The Pediatric infectious disease journal

Content:

Date:

2017-03-01

Authors:

GBD 2017 Inflammatory Bowel Disease Collaborators

Journal:

The lancet. Gastroenterology & hepatology

Content:

Date:

2019-10-01

Authors:

Mohsen Mazidi Andre Pascal Kengne Hassan Vatanparast

Journal:

Oxidative Medicine and Cellular Longevity

Content:

Date:

2017-01-01

Authors:

Uthman OA Nduka C Watson SI Mills EJ Kengne AP Jaffar SS Clarke A Moradi T Ekström AM Lilford R

Journal:

BMC infectious diseases

Content:

Date:

2018-06-01

Authors:

NCD Risk Factor Collaboration (NCD-RisC)

Journal:

Nature

Content:

Date:

2019-05-01

Authors:

Steve Raoul Ngongang Noumegni Jobert Richie Nansseu Vicky Jocelyne Moor Ama Jean Joel Bigna Felix Kembe Assah Magellan Guewo-Fokeng Steve Leumi Jean-Claude Katte Mesmin Dehayem Andre Pascal Kengne Eugene Sobngwi

Journal:

Content:

Abstract Background Little is known on the magnitude and correlates of insulin resistance in HIV-infected people in Africa. We determined the prevalence of insulin resistance and investigated associated factors in HIV-infected adult Cameroonians. Methods We conducted a cross-sectional study at the Yaoundé Central Hospital, Cameroon; during which we enrolled HIV-infected people aged 30 to 74 years with no previous history of cardiovascular disease. An homeostatic model assessment of insulin resistance (HOMA-IR) like index served to assess insulin sensitivity with insulin resistance defined by values of 2.1 or higher. Results We included 452 patients (20% men). Their mean age was 44.4 ± 9.8 years and 88.5% of them were on antiretroviral therapy (93.3% on first line regimen including Zidovudine, lamivudine and Efavirenz/Nevirapine). Of all participants, 28.5% were overweight, 19.5% had obesity and 2.0% had diabetes. The prevalence of insulin resistance was 47.3% without any difference between patients on ART and those ART-naïve (48.5% vs. 38.5%; p = 0.480). Obesity was the only factor independently associated with insulin resistance (adjusted odds ratio: 2.28; 95% confidence interval: 1.10–4.72). Conclusion Insulin resistance is present in nearly half of HIV-infected patients in Cameroon despite a low prevalence rate of diabetes, and is associated with obesity.

Date:

2017-01-01

Authors:

Andre Pascal Kengne Anushka Patel

Journal:

Content:

Date:

2006-01-01

Authors:

Kuguyo O Kengne AP Dandara C

Journal:

Omics : a journal of integrative biology

Content:

Date:

2020-06-01

Authors:

Mohsen Mazidi Andre Pascal Kengne Dimitri P. Mikhailidis Arrigo F. Cicero Maciej Banach

Journal:

Content:

Abstract ; Background and aim: Growing evidence suggests that some of the effects of diet on cardiovascular disease (CVD) occur through mechanisms involving subclinical inflammation. We assessed the relationship between selected dietary constituents and serum high-sensitivity C-reactive protein (hsCRP) concentration in a population-based sample of United States adults. Methods: In this cross-sectional analysis, participants were selected from the US National Health and Nutrition Examination Survey (NHANES) and restricted to those with available data on dietary intake, biochemical and anthropometric measurements from 2001 to 2010. All statistical analyses accounted for the survey design and sample weights by using SPSS Complex Samples v22.0 (IBM Corp, Armonk, NY). Results: Of the 17,689 participants analysed, 8607 (48.3%) were men. The mean age was 45.8 years in the overall sample, 44.9 in men and 46.5 in women ( p = .047). The age-, race-, sex-, energy intake- and body mass index-adjusted mean dietary intakes of total dietary fibre, polyunsaturated fatty-acids, vitamin E, vitamin A, vitamin B6, total folate, vitamin B family, vitamin C, vitamin K, magnesium, iron, copper and potassium monotonically decreased across increasing hsCRP quarters ( p < .001 for all), whereas sugar intake increased ( p < .001). In analysis of covariance adjusted for potential confounders (age-, race-, sex-, energy intake- and body weight-) hsCRP levels increased across increasing quarters of sugar intake ( p < .001). Conclusions: This study provides further evidence of an association between dietary sugar, polyunsaturated fatty-acids, fibre and antioxidant intake and hsCRP levels, a subclinical inflammation marker. hsCRP concentrations are likely modulated by dietary intake.KEY MESSAGES Serum high-sensitivity C-reactive protein (hsCRP) concentration is positively associated with sugar intake, and negatively with the consumption of minerals, vitamins and polyunsaturated fatty-acids (fruit and vegetables). hsCRP concentrations, and accordingly subclinical inflammation, are likely influenced by dietary intake. Serum high-sensitivity C-reactive protein (hsCRP) concentration is positively associated with sugar intake, and negatively with the consumption of minerals, vitamins and polyunsaturated fatty-acids (fruit and vegetables). hsCRP concentrations, and accordingly subclinical inflammation, are likely influenced by dietary intake.

Date:

2017-01-01

Authors:

Dzudie A Rayner B Ojji D Schutte AE Twagirumukiza M Damasceno A Ba SA Kane A Kramoh E Anzouan Kacou JB Onwubere B Cornick R Sliwa K PASCAR Task Force on Hypertension

Journal:

Global heart

Content:

Date:

2017-10-01

Authors:

Balti EV Kengne AP Fokouo JVF Nouthé BE Sobngwi E

Journal:

PloS one

Content:

Date:

2013-12-01

Authors:

Chalmers J Kengne AP Joshi R Perkovic V Patel A

Journal:

Journal of hypertension. Supplement : official journal of the International Society of Hypertension

Content:

Date:

2007-06-01

Authors:

Kim Anh Nguyen Naeemah Abrahams Rachel Jewkes Shibe Mhlongo Soraya Seedat Bronwyn Myers Carl Lombard Claudia Garcia-Moreno Esnat Chirwa Andre Pascal Kengne Nasheeta Peer

Journal:

International Journal of Environmental Research and Public Health

Content:

Date:

2022-03-29

Authors:

Moloi MW Kajawo S Noubiap JJ Mbah IO Ekrikpo U Kengne AP Bello AK Okpechi IG

Journal:

BMJ open

Content:

Date:

2018-05-01

Authors:

Lekoubou A Philippeau F Derex L Olaru A Gouttard M Vieillart A Kengne AP

Journal:

Neurological research

Content:

Date:

2013-12-01

Authors:

Matsha TE Hassan MS Hon GM Soita DJ Kengne AP Erasmus RT

Journal:

International journal of cardiology

Content:

Date:

2013-05-01

Authors:

Matsha TE Kengne AP Masconi KL Yako YY Erasmus RT

Journal:

BMC genetics

Content:

Date:

2015-06-01

Authors:

Matsha TE Yako YY Rensburg MA Hassan MS Kengne AP Erasmus RT

Journal:

BMC nephrology

Content:

Date:

2013-04-01

Authors:

Mazidi M Shivappa N Wirth MD Hebert JR Kengne AP

Journal:

European journal of clinical nutrition

Content:

Date:

2018-11-01

Authors:

Eric Walter Pefura-Yone André Pascal Kengne Emmanuel Afane-Ze Christopher Kuaban

Journal:

Content:

Background German cockroach or Blattella germanica is commonly found in homes across the inter-tropical region. The contribution of sensitisation to Blattella germanica in people with asthma in sub-Saharan Africa has not received attention. The aim of this study was to assess the prevalence and investigate the predicting factors of sensitisation to Blattella germanica in patients with asthma in Yaounde, Cameroon.Methods This was a cross-sectional study conducted between January 2012 and June 2013. All patients (aged 15 years and above) with asthma, receiving care at the Yaounde Jamot Hospital and the CEDIMER medical practice during the study period and who had received a prick skin testing for perennial aeroallergens were included in the study.Results The final sample comprised 184 patients including 123 (66.8%) women. The median age (25th-75th percentiles) was 38 (24–54) years. Prick skin test for Blattella germanica was positive in 47 (25.5%) patients. Sensitisation to Blattella germanica was associated with a sensitisation to mite in 41 (87.2%) patients, a sensitisation to Alternaria in 18 (38.3%) patients, and a sensitisation to cat or dog dander in 7 (14.9%) patients. Independent predicting factors of a sensitisation to Blattella germanica were the sensitisation to Blomia tropicalis [adjusted odd ratio (95% confidence interval) 4.10 (1.67-10.04), p = 0.002] and sensitisation to Alternaria [3.67 (1.53-7.46), p = 0.003].Conclusions Sensitisation to Blattella germanica is present in about a quarter of adult patients with asthma in Yaounde. Sensitisation to Alternaria and Blomia tropicalis appears to be a powerful predicting factor of sensitisation to Blattella germanica in this setting. Keywords: Asthma, Blattella, Allergy, Aeroallergens, Africa

Date:

Authors:

Eric Walter Pefura-Yone Emmanuel Soh André Pascal Kengne Adamou Dodo Balkissou Christopher Kuaban

Journal:

Content:

Summary: Purpose: To assess the prevalence and determinants of non-adherence to antiretroviral therapy (ART) as well as the concordance of two screening criteria in a major center for human immunodeficiency virus (HIV) treatment in Yaounde, Cameroon. Methods: In 2011, we conducted a cross-sectional study involving a random sample of 889 adults (age > 18 years, 67.9% women) infected with HIV who were receiving chronic care at the Yaounde Jamot Hospital. Adherence was assessed via self-administered questionnaires using the Community Programs for Clinical Research on AIDS (CPCRA) index and the Center for Adherence Support Evaluation (CASE) index. Results: The prevalence of non-adherence to ART was 22.5% based on the CPCRA index and 34.9% based on the CASE index, with a low agreement between the two indexes [kappa = 0.37 (95% confidence interval 0.31–0.44)]. Independent determinants of CPCRA-diagnosed non-adherence were as follows: being a remunerated employee [odds ratio (95% confidence interval): 1.61 (1.14–2.28)], Pentecostal Christianity [2.18 (1.25–3.80)], alcohol consumption [1.65 (1.16–2.34)] and non-adherence to cotrimoxazole prophylaxis [5.73 (3.92–8.38)]. The equivalents for CASE-diagnosed non-adherence were [1.59 (1.19–2.12)], [1.83 (1.36–2.47)], [1.70 (1.27–2.28)], respectively, in addition to association with changes to the ART regimen [1.61 (1.17–2.20)]. Conclusions: Non-adherence to ART remains high in this population. The careful evaluation of patients for the presence of determinants of non-adherence identified in this study may aid ART optimization. Keywords: Antiretroviral therapy, Adherence, HIV infection, Cameroon

Date:

2013-01-01

Authors:

Riddell MA Edwards N Thompson SR Bernabe-Ortiz A Praveen D Johnson C Kengne AP Liu P McCready T Ng E Nieuwlaat R Ovbiagele B Owolabi M GACD Hypertension Research Programme

Journal:

Globalization and health

Content:

Date:

2017-03-01

Authors:

GBD 2017 Gastro-oesophageal Reflux Disease Collaborators

Journal:

The lancet. Gastroenterology & hepatology

Content:

Date:

2020-03-01

Authors:

Igwesi-Chidobe CN Godfrey EL Kengne AP

Journal:

BMJ open

Content:

Date:

2015-08-01

Authors:

Ataklte F Erqou S Kaptoge S Taye B Echouffo-Tcheugui JB Kengne AP

Journal:

Hypertension (Dallas, Tex. : 1979)

Content:

Date:

2014-11-01

Authors:

Wang H Liddell CA Coates MM Mooney MD Levitz CE Schumacher AE Apfel H Iannarone M Phillips B Lofgren KT Sandar L Dorrington RE Rakovac I Murray CJ

Journal:

Lancet (London, England)

Content:

Date:

2014-05-01

Authors:

Odukoya OO Ohazurike C Akanbi M O'Dwyer LC Isikekpei B Kuteyi E Ameh IO Osadiaye O Adebayo K Usinoma A Adewole A Odunukwe N Okuyemi K Kengne AP

Journal:

JMIR mHealth and uHealth

Content:

Date:

2021-06-01

Authors:

Kaze FF Kengne AP Atanga LC Monny Lobe M Menanga AP Halle MP Chetcha Chemegni B Ngo Sack F Kingue S Ashuntantang G

Journal:

Clinical kidney journal

Content:

Date:

2012-10-01

Authors:

GBD 2020 Release 1 Vaccine Coverage Collaborators

Journal:

Lancet (London, England)

Content:

Date:

2021-07-01

Authors:

Fezeu LK Assah FK Balkau B Mbanya DS Kengne AP Awah PK Mbanya JC

Journal:

Obesity (Silver Spring, Md.)

Content:

Date:

2008-03-01

Authors:

Kengne AP Dzudie AI Fezeu LL Mbanya JC

Journal:

The international journal of lower extremity wounds

Content:

Date:

2006-03-01

Authors:

Kengne AP Awah PK Fezeu L Mbanya JC

Journal:

African health sciences

Content:

Date:

2007-03-01

Authors:

Vergotine Z Kengne AP Erasmus RT Yako YY Matsha TE

Journal:

International journal of endocrinology

Content:

Date:

2014-08-01

Authors:

Aminde LN Takah NF Noubiap JJ Tindong M Ngwasiri C Jingi AM Kengne AP Dzudie A

Journal:

BMC public health

Content:

Date:

2015-11-01

Authors:

Moons KG Kengne AP Woodward M Royston P Vergouwe Y Altman DG Grobbee DE

Journal:

Heart (British Cardiac Society)

Content:

Date:

2012-03-01

Authors:

van Dieren S Kengne AP Chalmers J Beulens JW Cooper ME Grobbee DE Harrap S Mancia G Neal B Patel A Poulter N van der Schouw YT Woodward M Zoungas S

Journal:

Diabetes research and clinical practice

Content:

Date:

2012-06-01

Authors:

GBD 2016 Traumatic Brain Injury and Spinal Cord Injury Collaborators

Journal:

The Lancet. Neurology

Content:

Date:

2018-11-01

Authors:

Eric Vounsia Balti André Pascal Kengne Jean Valentin Fogha Fokouo Brice Enid Nouthé Eugene Sobngwi

Journal:

Content:

BACKGROUND AND PURPOSE: Determinants of post-acute stroke outcomes in Africa have been less investigated. We assessed the association of metabolic syndrome (MetS) and insulin resistance with post-stroke mortality in patients with first-ever-in-lifetime stroke in the capital city of Cameroon (sub-Saharan Africa). METHODS: Patients with an acute first-stroke event (n = 57) were recruited between May and October 2006, and followed for 5 years for mortality outcome. MetS definition was based on the Joint Interim Statement 2009, insulin sensitivity/resistance assessed via glucose-to-insulin ratio, quantitative insulin sensitivity check index and homeostatic model assessment. RESULTS: Overall, 24 (42%) patients deceased during follow-up. The prevalence of MetS was higher in patients who died after 28 days, 1 year and 5 years from any cause or cardiovascular-related causes (all p≤0.040). MetS was associated with an increased overall mortality both after 1 year (39% vs. 9%) and 5 years of follow-up (55% vs. 26%, p = 0.022). Similarly, fatal events due to cardiovascular-related conditions were more frequent in the presence of MetS both 1 year (37% vs. 9%) and 5 years after the first-ever-in-lifetime stroke (43% vs. 13%, p = 0.017). Unlike biochemical measures of insulin sensitivity and resistance (non-significant), in age- and sex-adjusted Cox models, MetS was associated with hazard ratio (95% CI) of 2.63 (1.03-6.73) and 3.54 (1.00-12.56) respectively for all-cause and cardiovascular mortality 5 years after stroke onset. CONCLUSION: The Joint Interim Statement 2009 definition of MetS may aid the identification of a subgroup of black African stroke patients who may benefit from intensification of risk factor management.

Date:

Authors:

Carmen Pheiffer Victoria Pillay-van Wyk Eunice Turawa Naomi Levitt Andre P. Kengne Debbie Bradshaw

Journal:

International Journal of Environmental Research and Public Health

Content:

Date:

2021-05-30

Authors:

Di Cesare M Sorić M Bovet P Miranda JJ Bhutta Z Stevens GA Laxmaiah A Kengne AP Bentham J

Journal:

BMC medicine

Content:

Date:

2019-11-01

Authors:

Muyunda Mutemwa Nasheeta Peer Anniza De Villiers Mieke Faber Andre-Pascal Kengne

Journal:

Southern African Journal of HIV Medicine

Content:

Date:

2020-04-21

Authors:

Peer N Naicker A Khan M Kengne AP

Journal:

SAGE open medicine

Content:

Date:

2020-07-01

Authors:

Anastase, Dzudie Suiru, Dzekem Andre, Pascal Kengne

Journal:

Content:

Date:

2017-01-01

Authors:

Macharia M Kengne AP Blackhurst DM Erasmus RT Matsha TE

Journal:

Journal of clinical pathology

Content:

Date:

2013-07-01

Authors:

NCD Risk Factor Collaboration (NCD-RisC)

Journal:

Nature

Content:

Date:

2020-06-01

Authors:

Kuate-Tegueu C Temfack E Ngankou S Doumbe J Djientcheu VP Kengne AP

Journal:

Journal of the neurological sciences

Content:

Date:

2015-05-01

Authors:

Davidson FE Matsha TE Erasmus RT Ismail S Kengne AP Goedecke JH

Journal:

European journal of clinical nutrition

Content:

Date:

2020-04-01

Authors:

NCD Risk Factor Collaboration (NCD-RisC)

Journal:

Lancet (London, England)

Content:

Date:

2021-08-01

Authors:

Davids SF Matsha TE Peer N Erasmus RT Kengne AP

Journal:

Frontiers in endocrinology

Content:

Date:

2019-11-01

Authors:

Aminde LN Dzudie A Kengne AP

Journal:

BMJ open

Content:

Date:

2016-02-01

Authors:

Kuate D Kengne AP Biapa CP Azantsa BG Abdul Manan Bin Wan Muda W

Journal:

Lipids in health and disease

Content:

Date:

2015-05-01

Authors:

Kengne AP Czernichow S Huxley R Grobbee D Woodward M Neal B Zoungas S Cooper M Glasziou P Hamet P Harrap SB Mancia G Poulter N ADVANCE Collaborative Group

Journal:

Hypertension (Dallas, Tex. : 1979)

Content:

Date:

2009-05-01

Authors:

Davidson FE Matsha TE Erasmus RT Kengne AP Goedecke JH

Journal:

Diabetology & metabolic syndrome

Content:

Date:

2019-11-01

Authors:

Peprah E Armstrong-Hough M Cook S Mukasa B Taylor J Xu H Chang L Gyamfi J Ryan N Ojo T Snyder A Iwelunmor J Ezechi O Iyegbe C Pascal Kengne A

Journal:

International journal of environmental research and public health

Content:

Date:

2021-03-01

Authors:

Kengne AP Dzudie A Sobngwi E

Journal:

Vascular health and risk management

Content:

Date:

2008-01-01

Authors:

Yone EW Balkissou AD Kengne AP Kuaban C

Journal:

BMC pulmonary medicine

Content:

Date:

2012-08-01

Authors:

Adom T Puoane T De Villiers A Kengne AP

Journal:

BMJ open

Content:

Date:

2017-02-01

Authors:

Gary Maartens Annemie Stewart Rulan Griesel Andre P. Kengne Felix Dube Mark Nicol Molebogeng X. Rangaka Marc Mendelson

Journal:

Southern African Journal of HIV Medicine

Content:

Date:

2018-07-23

Authors:

Masoud M Kengne AP Erasmus RT Hon GM Macharia M Matsha TE

Journal:

Indian journal of clinical biochemistry : IJCB

Content:

Date:

2018-03-01

Authors:

Dzudie A Choukem SP Dehayem MY Kengne AP

Journal:

Journal of diabetes

Content:

Date:

2012-12-01

Authors:

Thomas B Matsushita K Abate KH Al-Aly Z Ärnlöv J Asayama K Atkins R Badawi A Ballew SH Banerjee A Barregård L Barrett-Connor E Basu S Global Burden of Disease Genitourinary Expert Group

Journal:

Journal of the American Society of Nephrology : JASN

Content:

Date:

2017-04-01

Authors:

Kengne AP Awah PK

Journal:

QJM : monthly journal of the Association of Physicians

Content:

Date:

2009-01-01

Authors:

Jillian Hill Camille Lavigne Delville Anne-Marie Auorousseau Deborah Jonathan Nasheeta Peer Brian Oldenburg Andre-Pascal Kengne

Journal:

International Journal of Environmental Research and Public Health

Content:

Date:

2020-01-30

Authors:

Mhandire D Mhandire K Magadze M Wonkam A Kengne AP Dandara C

Journal:

Content:

Date:

2020-05-01

Authors:

GBD 2016 Risk Factors Collaborators

Journal:

Lancet (London, England)

Content:

Date:

2017-09-01

Authors:

Malambo P Kengne AP Lambert EV De Villiers A Puoane T

Journal:

Journal of physical activity & health

Content:

Date:

2017-10-01

Authors:

Kaze FF Kengne AP Magatsing CT Halle MP Yiagnigni E Ngu KB

Journal:

Journal of clinical hypertension (Greenwich, Conn.)

Content:

Date:

2016-01-01

Authors:

Kaze FF Kengne AP Choukem SP Dzudie A Halle MP Dehayem MY Ashuntantang G

Journal:

American journal of kidney diseases : the official journal of the National Kidney Foundation

Content:

Date:

2008-06-01

Authors:

Mazidi M Ofori-Asenso R Kengne AP

Journal:

Journal of gastroenterology and hepatology

Content:

Date:

2020-05-01

Authors:

Nkoke C Balti E Menanga A Dzudie A Lekoubou A Kingue S Kengne AP

Journal:

Translational pediatrics

Content:

Date:

2017-01-01

Authors:

ADVANCE Collaborative Group Patel A MacMahon S Chalmers J Neal B Billot L Woodward M Marre M Cooper M Glasziou P Grobbee D Hamet P Travert F

Journal:

The New England journal of medicine

Content:

Date:

2008-06-01

Authors:

Nguyen KA Peer N Kengne AP.

Journal:

Content:

Date:

2021-01-01

Authors:

Ngwa EN Kengne AP Tiedeu-Atogho B Mofo-Mato EP Sobngwi E

Journal:

Diabetology & metabolic syndrome

Content:

Date:

2015-04-01

Authors:

George C Matsha TE Korf M Zemlin AE Erasmus RT Kengne AP

Journal:

BMC nephrology

Content:

Date:

2020-01-01

Authors:

Lekoubou A Clovis N Dzudie A Kengne AP

Journal:

Primary care diabetes

Content:

Date:

2016-07-01

Authors:

Olalekan A Uthman Chidozie U Nduka Mustapha Abba Rocio Enriquez Helena Nordenstedt Fred Nalugoda Andre P Kengne Anna M Ekström

Journal:

Content:

Date:

2017-11-16

Authors:

Andre Pascal Kengne Sébastien Czernichow Mark Hamer G David Batty Emmanuel Stamatakis

Journal:

Content:

Both anaemia and cardiovascular disease (CVD) are common in people with diabetes. While individually both characteristics are known to raise mortality risk, their combined influence has yet to be quantified. In this pooling project, we examined the combined impact of baseline haemoglobin levels and existing CVD on all-cause and CVD mortality in people with diabetes. We draw comparison of these effects with those apparent in diabetes-free individuals.A combined analyses of 7 UK population-based cohorts resulted in 26,480 study members. There were 946 participants with physician-diagnosed diabetes, 2227 with anaemia [haemoglobin<13 g/dl (men) or <12 (women)], 2592 with existing CVD (stroke, ischaemic heart disease), and 21,396 with none of the conditions. Across diabetes and anaemia subgroups, and using diabetes-free, non-anaemic participants as the referent group, the adjusted hazard ratios (HR) were 1.46 (95% CI: 1.30-1.63) for anaemia, 1.67 (1.45-1.92) for diabetes, and 2.10 (1.55-2.85) for diabetes and anaemia combined. Across combined diabetes, anaemia and CVD subgroups, and compared with non-anaemic, diabetes-free and CVD-free participants, HR (95% CI) for all-cause mortality were 1.49 (1.32-1.69) anaemia, 1.60 (1.46-1.76) for existing CVD, and 1.66 (1.39-1.97) for diabetes alone. Equivalents were 2.13 (1.48-3.07) for anaemia and diabetes, 2.68 (2.14-3.36) for diabetes and existing CVD, and 3.25 (1.88-5.62) for the three combined. Patterns were similar for CVD mortality.Individually, anaemia and CVD confer similar mortality risks in people with diabetes, and are excessively fatal in combination. Screening for anaemia would identify vulnerable diabetic patients whose outcomes can potentially be improved.

Date:

Authors:

Mazidi M Kengne AP

Journal:

Clinical nutrition (Edinburgh, Scotland)

Content:

Date:

2018-08-01

Authors:

Cecil J. Weale Glenda M. Davison Gloudina M. Hon Andre P. Kengne Rajiv T. Erasmus Tandi E. Matsha

Journal:

Cells

Content:

Date:

2019-05-16

Authors:

Eric Walter Pefura Yone Awa Foueudjeu Betyoumin André Pascal Kengne François Jérome Kaze Folefack Jeanne Ngogang

Journal:

Content:

First-line antiretroviral therapy and dyslipidemia in people living with HIV-1 in Cameroon: a cross-sectional study

Date:

Authors:

Dzudie A Aminde L Ngowe Ngowe M Takah N Luma HN Doualla MS Mapoure Y Mbatchou H Njamen TN Priso EB Kengne AP Sliwa-Hahnle K Nkwescheu AS Sone AM

Journal:

Cardiovascular journal of Africa

Content:

Date:

2014-09-01

Authors:

Mazidi M Kengne AP

Journal:

European journal of clinical investigation

Content:

Date:

2017-03-01

Authors:

Kaze AD Schutte AE Erqou S Kengne AP Echouffo-Tcheugui JB

Journal:

Journal of hypertension

Content:

Date:

2017-07-01

Authors:

Echouffo-Tcheugui JB Sobngwi E Kengne AP

Journal:

Archives of internal medicine

Content:

Date:

2012-03-01

Authors:

NCD Countdown 2030 collaborators

Journal:

Lancet (London, England)

Content:

Date:

2018-09-01

Authors:

Choukem SP Sih C Ntumsi AT Dimala CA Mboue-Djieka Y Ngouadjeu EDT Kengne AP

Journal:

BMC cardiovascular disorders

Content:

Date:

2020-03-01

Authors:

Kaze FF Njukeng FA Kengne AP Ashuntantang G Mbu R Halle MP Asonganyi T

Journal:

BMC pregnancy and childbirth

Content:

Date:

2014-04-01

Authors:

Steve Raoul Noumegni Jobert Richie Nansseu Jean Joel Bigna Vicky Jocelyne Ama Moor Felix Kembe Assah Mesmin Y Dehayem Andre Pascal Kengne Eugene Sobngwi

Journal:

Content:

Background The paucity of data regarding the association between atherogenic index of plasma and risk of cardiovascular disease in HIV-infected populations living in sub-Saharan Africa prompted us to conduct this study which aimed to assess the relationship between atherogenic index of plasma and risk of cardiovascular disease among a Cameroonian HIV-infected population. Methods This was a cross-sectional study conducted among 452 HIV-infected adults in Yaoundé, Cameroon. Risk of cardiovascular disease was calculated using the Framingham risk score; atherogenic index of plasma was derived as log (triglycerides/high-density lipoproteins cholesterol). Results Participants’ mean age (80% females) was 44.4 ± 9.8 years. Atherogenic index of plasma values ranged from –0.63 to 1.36 with a median of 0.11 (25th–75th percentiles: –0.08-0.31). Most participants (88.5%) were on antiretroviral treatment. There was a significant correlation between atherogenic index of plasma and fasting plasma glucose (r = 0.116; p = 0.014), atherogenic index of plasma and total cholesterol (r = –0.164; p < 0.001). Atherogenic index of plasma was significantly associated with the risk of cardiovascular disease either in univariable (β = 5.05, 95% CI: 3.31–6.79; p < 0.001, R 2 = 0.067) or in multivariable linear regression model after adjusting for socio-demographic, clinical and biological confounders (adjusted β = 3.79, 95% CI: 1.65 – 4.88; p < 0.001, R 2 = 0.187). Conclusion Atherogenic index of plasma may be an independent factor impacting the risk of cardiovascular disease among Cameroonian HIV-infected people. More studies are needed to better elucidate the association between atherogenic index of plasma and risk of cardiovascular disease in our setting.

Date:

2017-01-01

Authors:

GBD 2013 Mortality and Causes of Death Collaborators

Journal:

Lancet (London, England)

Content:

Date:

2014-12-01

Authors:

Moons KG Kengne AP Grobbee DE Royston P Vergouwe Y Altman DG Woodward M

Journal:

Heart (British Cardiac Society)

Content:

Date:

2012-03-01

Authors:

Andre Pascal Kengne Anastase Dzudie Eugene Sobngwi

Journal:

Content:

Andre Pascal Kengne1, Anastase Dzudie2, Eugene Sobngwi31The George Institute for International Health, University of Sydney, Australia; 2Heart failure and transplantation Unit, Louis Pradel’s Cardiovascular Hospital, Lyon, France; 3National Obesity Centre, Yaounde Central Hospital, CameroonPurpose: Heart failure is the ultimate complication of cardiac involvements in diabetes. The purpose of this review was to summarize current literature on heart failure among people with diabetes mellitus in sub-Saharan Africa (SSA).Method: Bibliographic search of published data on heart failure and diabetes in sub-Saharan Africa over the past 26 years.Results: Heart failure remains largely unexplored in general population and among people with diabetes in Africa. Heart failure accounts for over 30% of hospital admission in specialized cardiovascular units and 3%–7% in general internal medicine. Over 11% of adults with heart failure have diabetes. Risk factors for heart failure among those with diabetes include classical cardiovascular risk factors, without evidence of diabetes distinctiveness for other predictors common in Africa. Prevention, management, and outcomes of heart failure are less well known; recent data suggest improvement in the management of risk factors in clinical settings.Conclusions: Diabetes mellitus is growing in SSA. Related cardiovascular diseases are emerging as potential health problem. Heart failure as cardiovascular complication remains largely unexplored. Efforts are needed through research to improve our knowledge of heart failure at large in Africa. Multilevel preventive measures, building on evidences from other parts of the world must go along side.Keywords: diabetes mellitus, cardiovascular diseases, heart failure, sub-Saharan Africa

Date:

2008-01-01

Authors:

Alain Lekoubou Paschal Awah Leopold Fezeu Eugene Sobngwi Andre Pascal Kengne

Journal:

Content:

Chronic diseases are becoming increasingly important in sub-Saharan Africa (SSA). The current density and distribution of health workforce suggest that SSA cannot respond to the growing demand for chronic disease care, together with the frequent infectious diseases. Innovative approaches are therefore needed to rapidly expand the health workforce. In this article, we discuss the evidences in support of nurse-led strategies for chronic disease management in SSA, with a focus on hypertension and diabetes mellitus.

Date:

2010-01-01

Authors:

Kengne AP Masconi K Mbanya VN Lekoubou A Echouffo-Tcheugui JB Matsha TE

Journal:

Critical reviews in clinical laboratory sciences

Content:

Date:

2013-12-01

Authors:

Yone EW Kengne AP

Journal:

HIV/AIDS (Auckland, N.Z.)

Content:

Date:

2012-12-01

Authors:

Ruffieux N Njamnshi AK Mayer E Sztajzel R Eta SC Doh RF Kengne AM Ngamaleu RN Chanal J Verdon V Hauert CA

Journal:

Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence

Content:

Date:

2009-04-01

Authors:

George C Matsha TE Erasmus RT Kengne AP

Journal:

BMJ open

Content:

Date:

2018-11-01

Authors:

Camara A Baldé NM Sobngwi-Tambekou J Kengne AP Diallo MM Tchatchoua AP Kaké A Sylvie N Balkau B Bonnet F Sobngwi E

Journal:

Diabetes research and clinical practice

Content:

Date:

2014-09-01

Authors:

Mazidi M Kengne AP Katsiki N Mikhailidis DP Banach M

Journal:

Journal of diabetes and its complications

Content:

Date:

2017-10-01

Authors:

Lekoubou Looti AZ Kengne AP Djientcheu Vde P Kuate CT Njamnshi AK

Journal:

Journal of neurology, neurosurgery, and psychiatry

Content:

Date:

2010-07-01

Authors:

Peer N George C Kengne AP

Journal:

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde

Content:

Date:

2019-12-01

Authors:

Clement N. Kufe Lisa K. Micklesfield Maphoko Masemola Tinashe Chikowore Andre Pascal Kengne Fredrik Karpe Shane A. Norris Nigel J. Crowther Tommy Olsson Julia H. Goedecke

Journal:

Content:

Date:

2021-10-26

Authors:

GBD 2015 Mortality and Causes of Death Collaborators

Journal:

Lancet (London, England)

Content:

Date:

2016-10-01

Authors:

Theodosia Adom Anniza De Villiers Thandi Puoane André Pascal Kengne

Journal:

Nutrients

Content:

Date:

2021-11-11

Authors:

Duan D Kengne AP Echouffo-Tcheugui JB

Journal:

Endocrinology and metabolism clinics of North America

Content:

Date:

2021-07-01

Authors:

Mutemwa M Peer N de Villiers A Mukasa B Matsha TE Mills EJ Kengne AP

Journal:

Medicine

Content:

Date:

2018-08-01

Authors:

Choukem SP Dzudie A Dehayem M Halle MP Doualla MS Luma H Kengne AP

Journal:

The Pan African medical journal

Content:

Date:

2012-04-01

Authors:

Nguyen KA Peer N Mills EJ Kengne AP

Journal:

PloS one

Content:

Date:

2016-03-01

Authors:

Mohsen Mazidi Andre Pascal Kengne L. J. Cheskin Maciej Banach

Journal:

Content:

Abstract Background To examine the association between serum concentrations of antioxidant and telomere length (TL) in U.S adults. Methods Participants of the National Health and Nutrition Examination Survey (NHANES) with data available on TL measures from 2001 to 2002 were included. Serum lipophilic antioxidants level was measured using high performance liquid chromatography with photodiode array detection. We used analysis of co-variance and multivariable-adjusted linear regression models, accounting for the survey design and sample weights. Results Of the 5992 eligible participants, 47.5% (n = 2844) were men. The mean age was 46.9 years overall, 47.2 years in men and 46.6 in women (p = 0.071). In age, sex, race, education, marital status, adiposity, smoking, C-reactive protein adjusted linear regressions, antioxidant, serum α-carotene, trans-β-carotene, cis- β-carotene, β-cryptoxanthin and combined Lutein/zeaxanthin were positively and significantly associated with TL (all p < 0.001). Conclusions Our findings support a possible positive association between serum concentrations of lipophylic antioxidant and TL. The implications of this association deserve further investigation.

Date:

2018-01-01

Authors:

Mazidi M Shivappa N Wirth MD Hebert JR Vatanparast H Kengne AP

Journal:

European journal of clinical nutrition

Content:

Date:

2017-10-01

Authors:

Pefura-Yone EW Mbele-Onana CL Balkissou AD Kenmegne-Noumsi EC Boulleys-Nana JR Kolontchang-Yomi BL Theubo-Kamgang BJ Ndjeutcheu-Moualeu PI for Groupe Enquête en Santé Respiratoire au Cameroun (GESRC)

Journal:

The Journal of asthma : official journal of the Association for the Care of Asthma

Content:

Date:

2015-07-01

Authors:

Kassebaum NJ Bertozzi-Villa A Coggeshall MS Shackelford KA Steiner C Heuton KR Gonzalez-Medina D Barber R Huynh C Dicker D Templin T Lozano R

Journal:

Lancet (London, England)

Content:

Date:

2014-05-01

Authors:

Odukoya OO Ohazurike C Akanbi M O'Dwyer LC Isikekpei B Kuteyi E Ameh IO Osadiaye O Adebayo K Usinoma A Adewole A Odunukwe N Okuyemi K Kengne AP.

Journal:

Content:

Date:

2021-01-01

Authors:

Ibrahim Chikowe Victor Mwapasa Andre Pascal Kengne

Journal:

Content:

Abstract Objective There is limited data on the quality of primary care management for diabetes mellitus across Africa. The study was aimed at assessing the availability of basic supplies for the rapid diagnosis, treatment and management of diabetes in Malawian rural health facilities. This cross-sectional study was conducted in 55 public and private health centers from 19 districts using a structured questionnaire and checklist to interview the pharmacy personnel or officer in-charge of the health centers. We focused on availability of information, diagnosis and treatment materials for diabetes. Results Of the 55 health facilities surveyed, 21, 23 and 11 were located in the central, southern and northern regions of Malawi, respectively. Overall, 38% (21/55) of the health centres had glucometers, while 24% (13/55) had urine glucose dipsticks. Only 4% (2/55) of the health centres had recommended first-line medicines for treatment of type 1 and type 2 diabetes. No health centre had diabetes patient records and information, education and communication materials. Most rural health centers in Malawi lack basic health commodities for the screening, diagnosis and treatment of diabetes and this impedes on their effective management of growing diabetes burden. Therefore, health care systems need to adequately equip primary care facilities.

Date:

2018-01-01

Authors:

Kaze FF Halle MP Mopa HT Ashuntantang G Fouda H Ngogang J Kengne AP

Journal:

BMC nephrology

Content:

Date:

2015-07-01

Authors:

Pefura-Yone EW Kengne AP Balkissou AD Magne-Fotso CG Ngo-Yonga M Boulleys-Nana JR Efe-de-Melingui NR Ndjeutcheu-Moualeu PI Mbele-Onana CL Respiratory Health Survey Group in Cameroon (RHSGC)

Journal:

BMC research notes

Content:

Date:

2016-02-01

Authors:

Noumegni SR Ama VJM Assah FK Bigna JJ Nansseu JR Kameni JAM Katte JC Dehayem MY Kengne AP Sobngwi E

Journal:

Tropical diseases, travel medicine and vaccines

Content:

Date:

2017-07-01

Authors:

Gouda HN Charlson F Sorsdahl K Ahmadzada S Ferrari AJ Erskine H Leung J Santamauro D Lund C Aminde LN Mayosi BM Kengne AP Harris M Whiteford H

Journal:

The Lancet. Global health

Content:

Date:

2019-10-01

Authors:

Kengne AP Ntsekhe M

Journal:

Circulation

Content:

Date:

2018-05-01

Authors:

Masconi KL Echouffo-Tcheugui JB Matsha TE Erasmus RT Kengne AP

Journal:

Expert review of endocrinology & metabolism

Content:

Date:

2015-02-01

Authors:

GBD 2016 DALYs and HALE Collaborators

Journal:

Lancet (London, England)

Content:

Date:

2017-09-01

Authors:

Goedecke JH Mtintsilana A Dlamini SN Kengne AP

Journal:

Diabetes research and clinical practice

Content:

Date:

2016-12-01

Authors:

Kengne AP Limen SN Sobngwi E Djouogo CF Nouedoui C

Journal:

Diabetology & metabolic syndrome

Content:

Date:

2012-05-01

Authors:

Kaze FF Maimouna M Beybey AF Pefura-Yone EW Balkissou AD Halle MP Kowo MP Ashuntantang G Kengne AP

Journal:

Clinical and experimental nephrology

Content:

Date:

2021-03-01

Authors:

Peer N Kengne AP Motala AA Mbanya JC

Journal:

Diabetes research and clinical practice

Content:

Date:

2013-12-01

Authors:

Kengne AP Sobngwi E Fezeu LL Awah PK Dongmo S Mbanya JC

Journal:

The Journal of asthma : official journal of the Association for the Care of Asthma

Content:

Date:

2008-08-01

Authors:

Jun Hata Hisatomi Arima Sophia Zoungas Greg Fulcher Carol Pollock Mark Adams John Watson Rohina Joshi Andre Pascal Kengne Toshiharu Ninomiya Craig Anderson Mark Woodward Anushka Patel Giuseppe Mancia Neil Poulter Stephen MacMahon John Chalmers Bruce Neal

Journal:

Content:

Endpoint adjudication committees (EPAC) are widely used in clinical trials. The aim of the present analysis is to assess the effects of the endpoint adjudication process on the main findings of the ADVANCE trial (Trial registration: ClinicalTrials.gov NCT00145925).The ADVANCE trial was a multicentre, 2 × 2 factorial randomised controlled trial of blood pressure lowering and intensive blood glucose control in 11140 patients with type 2 diabetes. Primary outcomes were major macrovascular (nonfatal myocardial infarction, nonfatal stroke and cardiovascular death) and microvascular (new or worsening nephropathy and retinopathy) events. Suspected primary outcomes were initially reported by the investigators at the 215 sites with subsequent adjudication by the EPAC. The EPAC also adjudicated upon potential events identified directly by ongoing screening of all reported events. Over a median follow-up of 5 years, the site investigators reported one or more primary outcomes among 2443 participants. After adjudication these events were confirmed for 2077 (85%) with 48 further events added through the EPAC-led database screening process. The estimated relative risk reductions (95% confidence intervals) in the primary outcome for the blood pressure lowering comparison were 8% (-1 to 15%) based on the investigator-reported events and 9% (0 to 17%) based on the EPAC-based events (P for homogeneity = 0.70). The corresponding findings for the glucose comparison were 8% (1 to 15%) and 10% (2% to 18%) (P for homogeneity = 0.60). The effect estimates were also highly comparable when studied separately for macrovascular events and microvascular events for both comparisons (all P for homogeneity>0.6).The endpoint adjudication process had no discernible impact on the main findings in ADVANCE. These data highlight the need for careful consideration of the likely impact of an EPAC on the findings and conclusions of clinical trials prior to their establishment.

Date:

Authors:

Dzudie A Njume E Mfekeu LK Djomou A Ba H Ndom MS Nkoke C Ndongo S Boombhi J Kamdem F Mouandjo JPD Mouliom SA Kouam CK Meli H Monkam Y Cameroon Cardiac Society and MMM Cameroon investigator group

Journal:

European heart journal supplements : journal of the European Society of Cardiology

Content:

Date:

2021-05-01

Authors:

Journal:

Circulation

Content:

BACKGROUND: Cardiovascular disease, the major cause of mortality and morbidity in modern societies, is set to overtake infectious diseases in the developing world as the most common cause of death. The increasing prevalence of major and emerging cardiovascular risk factors accounts for the growing burden of cardiovascular disease in the world. Diabetes in all its forms is one of the main cardiovascular risk factors. Two of 3 diabetic patients will die as a result of cardiovascular complications, and approximately 30% of patients treated in cardiovascular intensive care units have diabetes. METHODS AND RESULTS: This review on the cardiovascular complications of diabetes in sub-Saharan Africa is a bibliographical MEDLINE search of published data over the past 2 decades. Diabetes-related cardiovascular disease complications are considered to be rare in Africa but are on the rise and are regularly associated with classic cardiovascular risk factors. Coronary heart disease may affect 5% to 8% of type 2 diabetic patients and cardiomyopathy, up to 50% of all patients. Close to 15% of patients with stroke have diabetes, and up to 5% of diabetic patients present with cerebrovascular accidents at diagnosis. Peripheral vascular disease prevalence varies across sites from 4% to 28%. CONCLUSIONS: It is obvious that diabetes mellitus and related cardiovascular complications are gaining more importance in sub-Saharan Africa. The relative contribution of putative risk factors is not well defined, and further research is therefore needed.

Date:

2005-12-01

Authors:

Halle MP Zebaze PN Mbofung CM Kaze F Mbiatat H Ashuntantang G Kengne AP

Journal:

Journal of nephrology

Content:

Date:

2014-01-01

Authors:

Echouffo-Tcheugui JB Kengne AP

Journal:

Diabetes & metabolism

Content:

Date:

2013-09-01

Authors:

Mohsen Mazidi Hong-kai Gao Andre Pascal Kengne

Journal:

Journal of Nutrition and Metabolism

Content:

Date:

2017-01-01

Authors:

Tandi E. Matsha Saaiga Ismail Aladdin Speelman Gloudina M. Hon Saarah Davids Rajiv T. Erasmus Andre P. Kengne

Journal:

Clinical Nutrition ESPEN

Content:

Date:

2019-08-01

Authors:

Noubiap JJ Nansseu JR Bigna JJ Jingi AM Kengne AP

Journal:

BMJ open

Content:

Date:

2015-03-01

Authors:

Noubiap JJ Agbaedeng TA Ndoadoumgue AL Nyaga UF Kengne AP

Journal:

Journal of cardiovascular electrophysiology

Content:

Date:

2021-05-01

Authors:

GBD 2015 Child Mortality Collaborators

Journal:

Lancet (London, England)

Content:

Date:

2016-10-01

Authors:

Eric Walter Pefura-Yone Adamou Dodo Balkissou Virginie Poka-Mayap Hadja Koté Fatime-Abaicho Patrick Thierry Enono-Edende André Pascal Kengne

Journal:

Content:

Abstract Background Death under care is a major challenge for tuberculosis (TB) treatment programs. We derived and validated a simple score to predict mortality during tuberculosis treatment in high endemicity areas. Methods We used data for patients aged ≥15 years, diagnosed and treated for tuberculosis at the Yaounde Jamot Hospital between January 2012 and December 2013. Baseline characteristics associated with mortality were investigated using logistic regressions. A simple prognosis score (CABI) was constructed with regression coefficients for predictors in the final model. Internal validation used bootstrap resampling procedures. Models discrimination was assessed using c-statistics and calibration assessed via calibration plots and the Hosmer and Lemeshwow (H-L) statistics. The optimal score was based on the Youden’s index. Results A total of 2250 patients (men 57.2%) with a mean age of 35.8 years were included; among whom 213 deaths (cumulative incidence 9.5%) were recorded. Clinical form of tuberculosis (C), age (A, years), adjusted body mass index (B, BMI, kg/m2) and status for HIV (Human immunodefiency virus) infection (I) were significant predictors in the final model (p < 0.0001) which was of the form Death risk = 1/(1 + e − (−1.3120 + 0.0474 ∗ age − 0.1866 ∗ BMI + 1.1637 (if smear negative TB) + 0.5418(if extra − pulmonary TB) + 1.3820(if HIV+))). The c-statistic was 0.812 in the derivation sample and 0.808 after correction for optimism. The calibration was good [H-Lχ2 = 6.44 (p = 0.60)]. The optimal absolute risk threshold was 4.8%, corresponding to a sensitivity of 81% and specificity of 67%. Conclusions The preliminary promising findings from this study require confirmation through independent external validation studies. If confirmed, the model derived could facilitate the stratification of TB patients for mortality risk and implementation of additional monitoring and management measures in vulnerable patients.

Date:

2017-01-01

Authors:

Khazdouz M Mazidi M Ehsaei MR Ferns G Kengne AP Norouzy AR

Journal:

Journal of dietary supplements

Content:

Date:

2017-05-01

Authors:

Arthemon Nguweneza Chandré Oosterwyk Kambe Banda Victoria Nembaware Gaston Mazandu Andre P Kengne Ambroise Wonkam

Journal:

Expert Review of Hematology

Content:

Date:

2022-04-03

Authors:

Nguyen KA Peer N de Villiers A Mukasa B Matsha TE Mills EJ Kengne AP

Journal:

PloS one

Content:

Date:

2017-09-01

Authors:

Theodosia Adom André Pascal Kengne Anniza De Villiers Rose Boatin Thandi Puoane

Journal:

International Journal of Environmental Research and Public Health

Content:

Date:

2019-12-19

Authors:

Kengne AP Czernichow S Stamatakis E Hamer M Batty GD

Journal:

Diabetes & vascular disease research

Content:

Date:

2012-07-01

Authors:

Zemlin AE Matsha TE Kengne AP Hon G Erasmus RT

Journal:

Journal of medical biochemistry

Content:

Date:

2016-10-01

Authors:

George C Goedecke JH Crowther NJ Jaff NG Kengne AP Norris SA Micklesfield LK

Journal:

PloS one

Content:

Date:

2016-05-01

Authors:

Businge CB Madini N Longo-Mbenza B Kengne AP

Journal:

BMJ open

Content:

Date:

2019-05-01

Authors:

Global Burden of Disease Study 2013 Collaborators

Journal:

Lancet (London, England)

Content:

Date:

2015-06-01

Authors:

Kanmogne GD Fonsah JY Umlauf A Moul J Doh RF Kengne AM Tang B Tagny CT Nchindap E Kenmogne L Franklin D Njamnshi DM Kuate CT Mbanya D Heaton RK

Journal:

Scientific reports

Content:

Date:

2020-08-01

Authors:

Gertrude Nsorma Nyaaba Karien Stronks Ama de-Graft Aikins Andre Pascal Kengne Charles Agyemang

Journal:

Content:

Abstract Background Half of the estimated annual 28 million non-communicable diseases (NCDs) deaths in low- and middle-income countries (LMICs) are attributed to weak health systems. Current health policy responses to NCDs are fragmented and vertical particularly in the African region. The World Health Organization (WHO) led NCDs Global action plan 2013–2020 has been recommended for reducing the NCD burden but it is unclear whether Africa is on track in its implementation. This paper synthesizes Africa’s progress towards WHO policy recommendations for reducing the NCD burden. Methods Data from the WHO 2011, 2014 and 2015 NCD reports were used for this analysis. We synthesized results by targets descriptions in the three reports and included indicators for which we could trace progress in at least two of the three reports. Results More than half of the African countries did not achieve the set targets for 2015 and slow progress had been made towards the 2016 targets as of December 2013. Some gains were made in implementing national public awareness programmes on diet and/or physical activity, however limited progress was made on guidelines for management of NCD and drug therapy and counselling. While all regions in Africa show waning trends in fully achieving the NCD indicators in general, the Southern African region appears to have made the least progress while the Northern African region appears to be the most progressive. Conclusion Our findings suggest that Africa is off track in achieving the NCDs indicators by the set deadlines. To make sustained public health gains, more effort and commitment is urgently needed from governments, partners and societies to implement these recommendations in a broader strategy. While donors need to suit NCD advocacy with funding, African institutions such as The African Union (AU) and other sub-regional bodies such as West African Health Organization (WAHO) and various country offices could potentially play stronger roles in advocating for more NCD policy efforts in Africa.

Date:

2017-01-01

Authors:

Kajawo S Moloi MW Noubiap JJ Ekrikpo U Kengne AP Okpechi IG

Journal:

BMJ open

Content:

Date:

2018-04-01

Authors:

Kanmogne GD Fonsah JY Tang B Doh RF Kengne AM Umlauf A Tagny CT Nchindap E Kenmogne L Franklin D Njamnshi DM Mbanya D Njamnshi AK Heaton RK

Journal:

Scientific reports

Content:

Date:

2018-12-01

Authors:

Kajawo S Ekrikpo U Moloi MW Noubiap JJ Osman MA Okpechi-Samuel US Kengne AP Bello AK Okpechi IG

Journal:

Kidney international reports

Content:

Date:

2020-11-01

Authors:

Andre Pascal Kengne Anastase Dzudie Eugene Sobngwi Correspondence Andre Pascal Kengne

Journal:

Content:

Purpose: Heart failure is the ultimate complication of cardiac involvements in diabetes. The purpose of this review was to summarize current literature on heart failure among people with diabetes mellitus in sub-Saharan Africa (SSA). Method: Bibliographic search of published data on heart failure and diabetes in sub-Saharan Africa over the past 26 years. Results: Heart failure remains largely unexplored in general population and among people with diabetes in Africa. Heart failure accounts for over 30 % of hospital admission in specialized cardiovascular units and 3%–7 % in general internal medicine. Over 11 % of adults with heart failure have diabetes. Risk factors for heart failure among those with diabetes include classical cardiovascular risk factors, without evidence of diabetes distinctiveness for other predictors common in Africa. Prevention, management, and outcomes of heart failure are less well known; recent data suggest improvement in the management of risk factors in clinical settings. Conclusions: Diabetes mellitus is growing in SSA. Related cardiovascular diseases are emerging as potential health problem. Heart failure as cardiovascular complication remains largely unexplored. Efforts are needed through research to improve our knowledge of heart failure at large in Africa. Multilevel preventive measures, building on evidences from other parts of the world must go along side.

Date:

Authors:

Oluwatoyin I. Ameh Udeme E. Ekrikpo Andre-Pascal Kengne

Journal:

Kidney International Reports

Content:

Date:

2020-03-01

Authors:

Tesema AG Ajisegiri WS Abimbola S Balane C Kengne AP Shiferaw F Dangou JM Narasimhan P Joshi R Peiris D

Journal:

PloS one

Content:

Date:

2020-10-01

Authors:

Caleyachetty R Echouffo-Tcheugui JB Tait CA Schilsky S Forrester T Kengne AP

Journal:

The lancet. Diabetes & endocrinology

Content:

Date:

2015-05-01

Authors:

Dzudie A Njume E Abanda M Aminde L Hamadou B Dzekem B Azabji M Doualla MS Ngowe M Kengne AP

Journal:

PloS one

Content:

Date:

2020-03-01

Authors:

Peer N Kengne AP

Journal:

Global heart

Content:

Date:

2016-12-01

Authors:

Kengne AP Djouogo CF Dehayem MY Fezeu L Sobngwi E Lekoubou A Mbanya JC

Journal:

The international journal of lower extremity wounds

Content:

Date:

2009-12-01

Authors:

Haagsma JA James SL Castle CD Dingels ZV Fox JT Hamilton EB Liu Z Lucchesi LR Roberts NLS Sylte DO Adebayo OM Ahmadi A Ahmed MB Vos T

Journal:

Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention

Content:

Date:

2020-01-01

Authors:

Kengne AP Fezeu LL Awah PK Sobngwi E Dongmo S Mbanya JC

Journal:

Epilepsia

Content:

Date:

2008-09-01

Authors:

Mazidi M Gao HK Kengne AP

Journal:

Scientific reports

Content:

Date:

2018-07-01

Authors:

Motamed S Mazidi M Safarian M Ghayour-Mobarhan M Moohebati M Ebrahimi M Azarpazhooh MR Heidari-Bakavoli A Esmaily H Baghestani A Ferns GA

Journal:

ARYA atherosclerosis

Content:

Date:

2019-05-01

Authors:

Nembaware V Mazandu GK Hotchkiss J Safari Serufuri JM Kent J Kengne AP Anie K Munung NS Bukini D Bitoungui VJN Munube D Chirwa U Wonkam A

Journal:

Omics : a journal of integrative biology

Content:

Date:

2020-10-01

Authors:

Masconi K Matsha TE Erasmus RT Kengne AP

Journal:

Diabetology & metabolic syndrome

Content:

Date:

2015-05-01

Authors:

Kengne AP Choukem SP Dehayem YM Simo NL Fezeu LL Mbanya JC

Journal:

Journal of wound care

Content:

Date:

2006-09-01

Authors:

GBD 2017 Pancreatic Cancer Collaborators

Journal:

The lancet. Gastroenterology & hepatology

Content:

Date:

2019-10-01

Authors:

Pasmore Malambo Andre P. Kengne Estelle V. Lambert Anniza De Villers Thandi Puoane

Journal:

Advances in Epidemiology

Content:

Date:

2016-06-15

Authors:

Businge CB Longo-Mbenza B Kengne AP

Journal:

Public health nutrition

Content:

Date:

2020-08-01

Authors:

Francois FolefackKaze Andre-Pascal Kengne Eric Walter PefuraYone Nelly Sandra NdamFemben Gloria Ashuntantang

Journal:

Content:

As per guidelines and recommendations, screening for renal diseases should be performed at the time of diagnosis of human immuno-deficiency virus (HIV) infection; however, this remains largely unimplemented in many settings across Sub-Saharan Africa. We evaluated the renal function, urinalysis abnormalities and their correlates in HIV-infected individuals who were naïve to highly active antiretroviral therapy (HAART). This was a cross-sectional study of 2 months′ duration involving 104 HIV-infected outpatients naive to HAART (71 women, 68%) attending the HIV clinic of the Yaoundé General Hospital in Cameroon. Renal and urinalysis parameters were measured and the Student t-test and Fischer exact test were used to compare the groups of participants. The mean age and CD4 count were, respectively, 35 ± 10.7 years and 305 ± 202/mL. Fifty-six (54%) patients presented with stages 3 and 4 of HIV infection. Forty-three (41%) patients had urinalysis abnormalities, including proteinuria (36%), leukocyturia (13%) and hematuria (12%). Proteinuria was associated with increased age, advanced stage of HIV infection, decreased CD4 count, hematuria and renal failure (P <0.04). Hematuria and leukocyturia were associated with decreased CD4 count and advanced stage of HIV infection, respectively (P = 0.04). The mean estimated glomerular filtration (eGFR) rate was100.2 ± 32.7 mL/min; three (3%) patients had renal failure (eGFR <60 mL/min) and 45 (43%) patients had reduced kidney function 60 ≤eGFR ≤90 mL/min. There was a high prevalence of decreased kidney function and proteinuria among Cameroonian HIV-infected patients naïve to HAART. Indicators of the severity of HIV infection, including advanced stage and low CD4 count, were associated with urinalysis abnormalities.

Date:

2013-01-01

Authors:

Simo N Kuate-Tegueu C Ngankou-Tchankeu S Doumbe J Maiga Y Cesari M Dartigues JF Kengne AP Tabue-Teguo M

Journal:

PloS one

Content:

Date:

2020-10-01

Authors:

Eric Walter Pefura-Yone André Pascal Kengne Adamou Dodo Balkissou Julie Raïcha Boulleys-Nana Nelly Rachel Efe-de-Melingui Patricia Ingrid Ndjeutcheu-Moualeu Charles Lebon Mbele-Onana Elvira Christelle Kenmegne-Noumsi Barbara Linda Kolontchang-Yomi Boris Judicaël Theubo-Kamgang Emilienne Régine Ebouki Chrystelle Karen Djuikam-Kamga Christiane Gaelle Magne-Fotso Francine Amougou Liliane Mboumtou Martine Ngo-Yonga Elsie Linda Petchou-Talla Emmanuel Afane-Ze Christopher Kuaban

Journal:

Content:

Population-based estimates of asthma and allergic rhinitis in sub-Saharan African adults are lacking. We assessed the prevalence and determinants of asthma and allergic rhinitis in urban adult Cameroonians.A community-based survey was conducted from December 2013 to April 2014 among adults aged 19 years and above (N = 2,304, 57.3% women), selected through multilevel stratified random sampling across all districts of Yaounde (Capital city). Internationally validated questionnaires were used to investigate the presence of allergic diseases. Logistic regressions were employed to investigate the determinants of allergic conditions.Prevalence rates were 2.7% (95% CI: 2.1-3.4) for asthma-ever, 6.9% (5.9-7.9) for lifetime wheezing, 2.9% (92.2-3.6) for current wheezing and 11.4% (10.1-12.7) for self-reported lifetime allergic rhinitis; while 240 (10.4%) participants reported current symptoms of allergic rhinitis, and 125 (5.4%) had allergic rhino-conjunctivitis. The prevalence of current asthma medication use and self-reported asthma attack was 0.8 (0.4-1.2) and 1 (0.6-1.4) respectively. Multivariable adjusted determinants of current wheezing were signs of atopic eczema [2.91 (1.09-7.74)] and signs of allergic rhinitis [3.24 (1.83-5.71)]. Age group 31-40 years [0.27(0.09-0.78), p = 0.016] was an independent protective factor for wheezing. Determinants of current rhinitis symptoms were active smoking [2.20 (1.37-3.54), p<0.001], signs of atopic eczema [2.84 (1.48-5.46)] and current wheezing [3.02 (1.70-5.39)].Prevalence rates for asthma and allergic rhinitis among adults in this population were at the lower tails of those reported in other regions of the world. Beside the classical interrelation between allergic diseases found in this study, active smoking was an independent determinant of allergic rhinitis symptoms. Nationwide surveys are needed to investigate regional variations.

Date:

Authors:

Aminde LN Dzudie A Takah NF Ngu KB Sliwa K Kengne AP

Journal:

Cardiovascular diagnosis and therapy

Content:

Date:

2015-04-01

Authors:

Lopes T Zemlin AE Erasmus RT Faber M Kengne AP

Journal:

BMJ open

Content:

Date:

2020-06-01

Authors:

Werfalli M Engel ME Musekiwa A Kengne AP Levitt NS

Journal:

The lancet. Diabetes & endocrinology

Content:

Date:

2015-11-01

Authors:

Ndadza A Cindi Z Makambwa E Chimusa E Wonkam A Kengne AP Ntsekhe M Dandara C

Journal:

Omics : a journal of integrative biology

Content:

Date:

2018-12-01

Authors:

Masconi KL Matsha TE Echouffo-Tcheugui JB Erasmus RT Kengne AP

Journal:

The EPMA journal

Content:

Date:

2015-03-01

Authors:

Feteh VF Choukem SP Kengne AP Nebongo DN Ngowe-Ngowe M

Journal:

BMC nephrology

Content:

Date:

2016-03-01

Authors:

Davids SFG Matsha TE Peer N Erasmus RT Kengne AP

Journal:

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde

Content:

Date:

2019-06-01

Authors:

Rohina Joshi Mohammed Alim Andre Pascal Kengne Stephen Jan Pallab K Maulik David Peiris Anushka A Patel

Journal:

Content:

One potential solution to limited healthcare access in low and middle income countries (LMIC) is task-shifting- the training of non-physician healthcare workers (NPHWs) to perform tasks traditionally undertaken by physicians. The aim of this paper is to conduct a systematic review of studies involving task-shifting for the management of non-communicable disease (NCD) in LMIC.A search strategy with the following terms "task-shifting", "non-physician healthcare workers", "community healthcare worker", "hypertension", "diabetes", "cardiovascular disease", "mental health", "depression", "chronic obstructive pulmonary disease", "respiratory disease", "cancer" was conducted using Medline via Pubmed and the Cochrane library. Two reviewers independently reviewed the databases and extracted the data.Our search generated 7176 articles of which 22 were included in the review. Seven studies were randomised controlled trials and 15 were observational studies. Tasks performed by NPHWs included screening for NCDs and providing primary health care. The majority of studies showed improved health outcomes when compared with usual healthcare, including reductions in blood pressure, increased uptake of medications and lower depression scores. Factors such as training of NPHWs, provision of algorithms and protocols for screening, treatment and drug titration were the main enablers of the task-shifting intervention. The main barriers identified were restrictions on prescribing medications and availability of medicines. Only two studies described cost-effective analyses, both of which demonstrated that task-shifting was cost-effective.Task-shifting from physicians to NPHWs, if accompanied by health system re-structuring is a potentially effective and affordable strategy for improving access to healthcare for NCDs. Since the majority of study designs reviewed were of inadequate quality, future research methods should include robust evaluations of such strategies.

Date:

Authors:

Mashiane JT Monyeki KD Kengne AP Rosina NM Monyeki MS

Journal:

Cardiovascular journal of Africa

Content:

Date:

2018-09-01

Authors:

GBD 2017 Mortality Collaborators

Journal:

Lancet (London, England)

Content:

Date:

2018-11-01

Authors:

GBD 2017 Disease and Injury Incidence and Prevalence Collaborators

Journal:

Lancet (London, England)

Content:

Date:

2018-11-01

Authors:

Krishnamurthi RV deVeber G Feigin VL Barker-Collo S Fullerton H Mackay MT O'Callahan F Lindsay MP Kolk A Lo W Shah P Linds A Jones K GBD 2013 Stroke Panel Experts Group

Journal:

Neuroepidemiology

Content:

Date:

2015-10-01

Authors:

Macharia M Kengne AP Blackhurst DM Erasmus RT Matsha TE

Journal:

Mediators of Inflammation

Content:

Date:

2014-11-01

Authors:

Mbanya VN Echouffo-Tcheugui JB Akhtar H Mbanya JC Kengne AP

Journal:

Diabetology & metabolic syndrome

Content:

Date:

2015-03-01

Authors:

Ameh OI Okpechi IG Dandara C Kengne AP

Journal:

Omics : a journal of integrative biology

Content:

Date:

2017-03-01

Authors:

Park JJH Grais RF Taljaard M Nakimuli-Mpungu E Jehan F Nachega JB Ford N Xavier D Kengne AP Ashorn P Socias ME Bhutta ZA Mills EJ

Journal:

The Lancet. Global health

Content:

Date:

2021-05-01

Authors:

Caleyachetty R Thomas GN Kengne AP Echouffo-Tcheugui JB Schilsky S Khodabocus J Uauy R

Journal:

The American journal of clinical nutrition

Content:

Date:

2018-08-01

Authors:

Kengne AP Mayosi BM

Journal:

Cardiovascular journal of Africa

Content:

Date:

2013-05-01

Authors:

Pefura-Yone EW Kengne AP Tagne-Kamdem PE Afane-Ze E

Journal:

BMJ open

Content:

Date:

2014-07-01

Authors:

Ekrikpo UE Akpan EE Ekott JU Bello AK Okpechi IG Kengne AP

Journal:

BMJ open

Content:

Date:

2018-07-01

Authors:

Echouffo-Tcheugui JB Dzudie A Epacka ME Choukem SP Doualla MS Luma H Kengne AP

Journal:

Primary care diabetes

Content:

Date:

2012-06-01

Authors:

Pule GD Ngo Bitoungui VJ Chetcha Chemegni B Kengne AP Antonarakis S Wonkam A

Journal:

Omics : a journal of integrative biology

Content:

Date:

2015-09-01

Authors:

GBD 2016 Disease and Injury Incidence and Prevalence Collaborators

Journal:

Lancet (London, England)

Content:

Date:

2017-09-01

Authors:

Noubiap JJ Naidoo J Kengne AP

Journal:

World journal of diabetes

Content:

Date:

2015-06-01

Authors:

Irina, Balieva Anastase, Dzudie Friedrich, Thienemann Mahmoud, U Sani Andre, Pascal Kengne Karen, Sliwa Adriaan, A Voors Ana, O Mocumbi Kamilu, Karaye Okechukwu, S Ogah

Journal:

Content:

Date:

2017-01-01

Authors:

Ndadza A Muyambo S Mnta P Wonkam A Chimusa E Kengne AP Ntsekhe M Dandara C

Journal:

Journal of thrombosis and haemostasis : JTH

Content:

Date:

2021-08-01

Authors:

Dzudie A Hoover D Kim H Ajeh R Adedimeji A Shi Q Yone WP Nforniwe DN Njie KT Kengne AP Ebasone VP Barche B Cecile ZBA Nash D Yotebieng M Anastos K

Journal:

Content:

Date:

2020-08-01

Authors:

NCD Risk Factor Collaboration (NCD-RisC)

Journal:

eLife

Content:

Date:

2021-03-01

Authors:

Malambo P Kengne AP Lambert EV De Villers A Puoane T

Journal:

BMC public health

Content:

Date:

2017-02-01

Authors:

Dzudie A Kengne AP Thienemann F Sliwa K

Journal:

BMJ open

Content:

Date:

2014-07-01

Authors:

Joshi R Kengne AP Hersch F Weber MB McGuire H Patel A

Journal:

Content:

Date:

2018-09-01

Authors:

Boateng D Agyemang C Beune E Meeks K Smeeth L Schulze MB Addo J de-Graft Aikins A Galbete C Bahendeka S Danquah I Agyei-Baffour P Klipstein-Grobusch K

Journal:

International journal of cardiology

Content:

Date:

2018-01-01

Authors:

Georgia E. Ritchie Andre Pascal Kengne Bruce Neal

Journal:

Content:

OBJECTIVE — To assess the utility of a point-of-care (POC) capillary blood glucose measurement as compared with routine clinical parameters in predicting undiagnosed diabetes in a low-resource rural India setting. RESEARCH DESIGN AND METHODS — Nine hundred and ninety-four participants aged �30 years and stratified by age and sex were randomly selected from 20 villages in India. A clinical questionnaire, sampling for laboratory venous fasting plasma glucose (FPG), and POC capillary blood glucose assay were performed simultaneously. Diabetes diagnosis was based on the World Health Organization (WHO) definition using FPG. The capacity of the POC glucose to predict the presence of diabetes was assessed and compared with the questionnaire using area under the receiver operating characteristic curves (AUCs). RESULTS — The AUC for POC glucose alone in predicting diabetes was 0.869 (95 % CI 0.810–0.929). This was significantly better (P � 0.001 for AUC comparison) than the models based upon clinical variables alone (AUC for the best clinical model including age, BMI, hypertension, waist circumference: 0.694 [95 % CI 0.621–0.766]). POC glucose appropriately reclassified the risk of up to one-third of participants ranked according to the clinical models. Adding the clinical variables to the POC glucose assay did not significantly improve the discriminatory capability beyond that achieved with the POC glucose measurement alone (all P � 0.37). CONCLUSIONS — POC glucose testing appears to be a simple and reliable tool for identifying undiagnosed diabetes in a high-risk, resource-poor rural population. However, studies evaluating the cost effectiveness of introducing POC glucose testing are needed prior to widespread implementation. The prevalence of type 2 diabetes is rapidly increasing around the world (1). Developing countries are facing the largest increases both in absolute and relative terms (1). It is predicted that this will have devastating consequences on the economies and health systems of these countries. Successful prevention and

Date:

Authors:

Cindy George Tandi E Matsha Florence E Davidson Julia H Goedecke Rajiv T Erasmus Andre Pascal Kengne

Journal:

International Journal of Nephrology and Renovascular Disease

Content:

Date:

2020-05-01

Authors:

Mazidi M Kengne AP Banach M Lipid and Blood Pressure Meta-analysis Collaboration Group

Journal:

Pharmacological research

Content:

Date:

2017-08-01

Authors:

van der Leeuw J Visseren FL Woodward M Zoungas S Kengne AP van der Graaf Y Glasziou P Hamet P MacMahon S Poulter N Grobbee DE Chalmers J

Journal:

Hypertension (Dallas, Tex. : 1979)

Content:

Date:

2014-10-01

Authors:

Zoungas S Chalmers J Kengne AP Pillai A Billot L de Galan B Marre M Neal B Harrap S Poulter N Patel A

Journal:

Diabetes research and clinical practice

Content:

Date:

2010-06-01

Authors:

Aminde LN Dzudie A Kengne AP Ndjebet J Mapoh S Kuelang X Kamdem F Mbatchou Ngahane BH Doualla MS Ngu KB Sliwa K Thienemann F

Journal:

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde

Content:

Date:

2017-09-01

Authors:

Peer N Abrahams N Kengne AP

Journal:

Global heart

Content:

Date:

2020-09-01

Authors:

GBD 2017 HIV collaborators

Journal:

The lancet. HIV

Content:

Date:

2019-08-01

Authors:

Mohsen Mazidi Andre Pascal Kengne Hassan Vatanparast

Journal:

Content:

Background and Purpose. Leukocyte telomere length (LTL) is a biomarker of biologic age. Whether food security status modulates LTL is still unknown. We investigated the association between food security and LTL in participants of the 1999–2002 US National Health and Nutrition Examination Survey (NHANES). Methods. Analysis of covariance (ANCOVA) was used to evaluate the association between food security categories and LTL controlling for sex, race, and education and accounting for the survey design and sample weights. Results. We included 10,888 participants with 5228 (48.0%) being men. They were aged on average 44.1 years. In all, 2362 (21.7%) had less than high school, 2787 (25.6%) had achieved high school, while 5705 (52.5%) had done more than high school. In sex-, race-, and education-adjusted ANCOVA, average LTL (T/S ratio) for participants with high food security versus those with marginal, low, or very low food security was 1.32 versus 1.20 for the age group 25–35 years and 1.26 versus 1.11 for the 35–45 years, (p<0.001). Conclusion. The association between food insecurity and LTL shortening in young adults suggest that some of the future effects of food insecurity on chronic disease risk in this population could be mediated by telomere shortening.

Date:

2017-01-01

Authors:

Mohsen Mazidi Hong-kai Gao Nitin Shivappa Michael D. Wirth James R Hebert Andre Pascal Kengne

Journal:

Content:

Abstract Background It has been suggested that trans fatty acids (TFAs) play an important role in cardiovascular diseases. We investigated the association between plasma TFAs and the dietary inflammatory index (DII) ™ in US adults. Methods National Health and Nutrition Examination Survey (NHANES) participants with data on plasma TFAs measured from 1999 to 2010 were included. Energy-adjusted-DII ™ (E-DII ™) expressed per 1000 kcal was calculated from 24-h dietary recalls. All statistical analyses accounted for the survey design and sample weights. Results Of the 5446 eligible participants, 46.8% (n = 2550) were men. The mean age of the population was 47.1 years overall, 47.8 years for men and 46.5 years for women (p = 0.09). After adjustment for C-reactive protein, body-mass-index, smoking, race, age, education, and marital status in linear regressions, trans 9-hexadecenoic acid [β coefficient 0.068 (95% CI: 0.032 to 0.188)], trans 11-octadecenoic acid [β coefficient 0.143 (95% CI: 0.155 to 0.310)], trans 9-octadecenoic acid [β coefficient 0.122 (95% CI: 0.120 to 0.277)], trans 9, and trans 12-octadienoic acid [β coefficient 0.103 (95% CI: 0.090 to 0.247)] were positively associated with the DII (all p < 0.001). Conclusion The association of plasma TFAs with a marker of dietary inflammation suggests an underlying mechanism in the initiation and progression of cardiovascular diseases.

Date:

2017-01-01

Authors:

GBD 2016 Mortality Collaborators

Journal:

Lancet (London, England)

Content:

Date:

2017-09-01

Authors:

Davison GM Nkambule BB Mkandla Z Hon GM Kengne AP Erasmus RT Matsha TE

Journal:

Scientific reports

Content:

Date:

2017-01-01

Authors:

Emmanuel Peprah Bronwyn Myers Andre-Pascal Kengne Nasheeta Peer Omar El-Shahawy Temitope Ojo Barbara Mukasa Oliver Ezechi Juliet Iwelunmor Nessa Ryan Fatoumata Sakho John Patena Joyce Gyamfi

Journal:

International Journal of Environmental Research and Public Health

Content:

Date:

2022-01-19

Authors:

Kaze FF Maimouna M Beybey AF Pefura-Yone EW Balkissou AD Halle MP Kowo MP Ashuntantang G Kengne A

Journal:

Content:

Date:

2019-08-01

Authors:

W Tobe S Global Alliance for Chronic Diseases Hypertension Research Teams With the World Hypertension League

Journal:

Journal of clinical hypertension (Greenwich, Conn.)

Content:

Date:

2016-06-01

Authors:

Nasheeta Peer Joel Msafiri Francis Anniza de Villiers Deborah Jonathan Cathy Kalombo Andre-Pascal Kengne

Journal:

PLOS ONE

Content:

Date:

2020-07-16

Authors:

Demir E Adeyemi S Kengne AP Kayode GA Adeoti A

Journal:

The International journal of health planning and management

Content:

Date:

2021-06-01

Authors:

Emmanuel Peprah Mari Armstrong-Hough Stephanie Cook Barbara Mukasa Jacquelyn Taylor Huichun Xu Linda Chang Joyce Gyamfi Nessa Ryan Temitope Ojo Anya Snyder Juliet Iwelunmor Oliver Ezechi Conrad Iyegbe Paul F. O'Reilly Andre Pascal Kengne

Journal:

International Journal of Environmental Research and Public Health

Content:

Date:

2021-03-01

Authors:

Mohsen Mazidi Richard J. Webb Gregory Y. H. Lip Andre P. Kengne Maciej Banach Ian G. Davies

Journal:

Journal of Clinical Medicine

Content:

Date:

2022-01-09

Authors:

Ashar Dhana Yohhei Hamada Andre P Kengne Andrew D Kerkhoff Tobias Broger Claudia M Denkinger Molebogeng X Rangaka Ankur Gupta-Wright Katherine Fielding Robin Wood Helena Huerga Sekai Chenai Mathabire Rücker Stephanie Bjerrum Isik S Johansen Swe Swe Thit Mar Mar Kyi Josh Hanson David A Barr Graeme Meintjes Gary Maartens

Journal:

Journal of Infection

Content:

Date:

2022-05-01

Authors:

Mohsen Mazidi Andre Pascal Kengne Dimitri P. Mikhailidis Arrigo F. Cicero Maciej Banach

Journal:

Content:

Abstract ; Background and aim: Growing evidence suggests that some of the effects of diet on cardiovascular disease (CVD) occur through mechanisms involving subclinical inflammation. We assessed the relationship between selected dietary constituents and serum high-sensitivity C-reactive protein (hsCRP) concentration in a population-based sample of United States adults. Methods: In this cross-sectional analysis, participants were selected from the US National Health and Nutrition Examination Survey (NHANES) and restricted to those with available data on dietary intake, biochemical and anthropometric measurements from 2001 to 2010. All statistical analyses accounted for the survey design and sample weights by using SPSS Complex Samples v22.0 (IBM Corp, Armonk, NY). Results: Of the 17,689 participants analysed, 8607 (48.3%) were men. The mean age was 45.8 years in the overall sample, 44.9 in men and 46.5 in women ( p = .047). The age-, race-, sex-, energy intake- and body mass index-adjusted mean dietary intakes of total dietary fibre, polyunsaturated fatty-acids, vitamin E, vitamin A, vitamin B6, total folate, vitamin B family, vitamin C, vitamin K, magnesium, iron, copper and potassium monotonically decreased across increasing hsCRP quarters ( p < .001 for all), whereas sugar intake increased ( p < .001). In analysis of covariance adjusted for potential confounders (age-, race-, sex-, energy intake- and body weight-) hsCRP levels increased across increasing quarters of sugar intake ( p < .001). Conclusions: This study provides further evidence of an association between dietary sugar, polyunsaturated fatty-acids, fibre and antioxidant intake and hsCRP levels, a subclinical inflammation marker. hsCRP concentrations are likely modulated by dietary intake.KEY MESSAGES Serum high-sensitivity C-reactive protein (hsCRP) concentration is positively associated with sugar intake, and negatively with the consumption of minerals, vitamins and polyunsaturated fatty-acids (fruit and vegetables). hsCRP concentrations, and accordingly subclinical inflammation, are likely influenced by dietary intake. Serum high-sensitivity C-reactive protein (hsCRP) concentration is positively associated with sugar intake, and negatively with the consumption of minerals, vitamins and polyunsaturated fatty-acids (fruit and vegetables). hsCRP concentrations, and accordingly subclinical inflammation, are likely influenced by dietary intake.

Date:

2017-01-01

Authors:

Czernichow S Ninomiya T Huxley R Kengne AP Batty GD Grobbee DE Woodward M Neal B Chalmers J

Journal:

Hypertension (Dallas, Tex. : 1979)

Content:

Date:

2010-03-01

Authors:

Mazidi M Shivappa N Wirth MD Hebert JR Kengne AP

Journal:

The British journal of nutrition

Content:

Date:

2018-07-01

Authors:

Dzudie A Kengne AP Lamont K Dzekem BS Aminde LN Abanda MH Thienemann F Sliwa K

Journal:

Cardiovascular journal of Africa

Content:

Date:

2018-11-01

Authors:

Fiona Turnbull Andre Pascal Kengne Stephen MacMahon

Journal:

Progress in Cardiovascular Diseases

Content:

Date:

2010-07-01

Authors:

LBD Double Burden of Malnutrition Collaborators

Journal:

Nature medicine

Content:

Date:

2020-08-01

Authors:

Kingue S Angandji P Menanga AP Ashuntantang G Sobngwi E Dossou-Yovo RA Kaze FF Kengne AP Dzudie A Ndobo P Muna W

Journal:

The Pan African medical journal

Content:

Date:

2013-08-01

Authors:

Choukem SP Manases T Nda-Mefoo JP Dimala CA Mboue-Djieka Y Sobngwi E Kengne AP

Journal:

Clinical biochemistry

Content:

Date:

2017-12-01

Authors:

Agoons DD Balti EV Kaze FF Azabji-Kenfack M Ashuntantang G Kengne AP Sobngwi E Mbanya JC

Journal:

Diabetic medicine : a journal of the British Diabetic Association

Content:

Date:

2015-11-01

Authors:

Kengne AP Echouffo-Tcheugui JB Sobngwi E

Journal:

Lancet (London, England)

Content:

Date:

2012-01-01

Authors:

Olalekan A Uthman Chidozie U Nduka Mustapha Abba Rocio Enriquez Helena Nordenstedt Fred Nalugoda Andre P Kengne Anna M Ekström

Journal:

JMIR mHealth and uHealth

Content:

Date:

2019-01-07

Authors:

Cuthbertson BH Croal BL Rae D Harrild K Gibson PH Prescott GJ Kengne AP Hillis GS

Journal:

British journal of anaesthesia

Content:

Date:

2012-11-01

Authors:

Jaspers Faijer-Westerink H Kengne AP Meeks KAC Agyemang C

Journal:

Nutrition, metabolism, and cardiovascular diseases : NMCD

Content:

Date:

2019-12-01

Authors:

Yone EW Kengne AP Moifo B Kuaban C

Journal:

Scandinavian journal of infectious diseases

Content:

Date:

2012-09-01

Authors:

Charles Bitamazire Businge Benjamin Longo-Mbenza Andre Pascal Kengne

Journal:

Annals of Medicine

Content:

Date:

2021-01-01

Authors:

Wendy Solomon Stanton Hector Shanel Raghubeer Rajiv Erasmus Andre Kengne Tandi Matsha

Journal:

Epigenomes

Content:

Date:

2020-09-01

Authors:

Kengne AP Patel A Colagiuri S Heller S Hamet P Marre M Pan CY Zoungas S Grobbee DE Neal B Chalmers J Woodward M ADVANCE Collaborative Group

Journal:

Diabetologia

Content:

Date:

2010-02-01

Authors:

GBD 2013 DALYs and HALE Collaborators Murray CJ Barber RM Foreman KJ Abbasoglu Ozgoren A Abd-Allah F Abera SF Aboyans V Abraham JP Vos T

Journal:

Lancet (London, England)

Content:

Date:

2015-08-01

Authors:

Balti EV Echouffo-Tcheugui JB Yako YY Kengne AP

Journal:

Diabetes research and clinical practice

Content:

Date:

2014-09-01

Authors:

Richard G Wamai Andre Pascal Kengne Naomi Levitt

Journal:

Content:

Date:

2018-01-01

Authors:

Boyles TH Kengne AP

Journal:

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease

Content:

Date:

2016-02-01

Authors:

Kengne AP Anderson CS

Journal:

International journal of stroke : official journal of the International Stroke Society

Content:

Date:

2006-11-01

Authors:

Pefura-Yone EW Fodjeu G Kengne AP Roche N Kuaban C

Journal:

Respiratory medicine

Content:

Date:

2014-12-01

Authors:

Cohen K Stewart A Kengne AP Leisegang R Coetsee M Maharaj S Dunn L Hislop M van Zyl G Meintjes G Maartens G

Journal:

Journal of acquired immune deficiency syndromes (1999)

Content:

Date:

2019-03-01

Authors:

Jean-Claude Mbanya Sylvestre Dongmo Paschal Kum Awah Leopold Fezeu Eugene Sobngwi Andre Pascal Kengne The CENHIP Investigators

Journal:

Content:

BACKGROUND: This article describes the setting-up process for nurse-led pilot clinics for the management of four chronic diseases: asthma, type 2 diabetes mellitus, epilepsy and hypertension at the primary health care level in urban and rural Cameroon. METHODS: The Biyem-Assi urban and the Bafut rural health districts in Cameroon served as settings for this study. International and local guidelines were identified and adapted to the country's; circumstances. Training and follow-up tools were developed and nurses trained by experienced physicians in the management of the four conditions. Basic diagnostic and follow-up materials were provided and relevant essential drugs made available. RESULTS: Forty six nurses attended six training courses. By the second year of activity, three and four clinics were operational in the urban and the rural areas respectively. By then, 925 patients had been registered in the clinics. This represented a 68.5% increase from the first year. While the rural clinics relied mainly on essential drugs for their prescriptions, a prescription pattern combining generic and proprietary drugs was observed in the urban clinics. CONCLUSION: In the quest for cost-effective health care for NCD in sub-Saharan Africa, rethinking health workforce and service delivery has relevance. Nurse-led clinics, algorithm driven service delivery stands as alternatives to overcome the shortage of trained physicians and other issues relating to access to care.

Date:

2009-01-01

Authors:

Businge CB Musarurwa HT Longo-Mbenza B Kengne AP

Journal:

Content:

Date:

2021-03-01

Authors:

Abrahams N Seedat S Lombard C Kengne AP Myers B Sewnath A Mhlongo S Ramjee G Peer N Garcia-Moreno C Jewkes R

Journal:

BMJ open

Content:

Date:

2017-09-01

Authors:

Camara A Baldé NM Diakité M Sylla D Baldé EH Kengne AP Baldé MD

Journal:

Journal of human hypertension

Content:

Date:

2015-08-01

Authors:

Matshazi DM Weale CJ Erasmus RT Kengne AP Davids SFG Raghubeer S Davison GM Matsha TE

Journal:

Molecular biology reports

Content:

Date:

2021-03-01

Authors:

GBD 2017 Colorectal Cancer Collaborators

Journal:

The lancet. Gastroenterology & hepatology

Content:

Date:

2019-10-01

Authors:

Simeon-Pierre Choukem Derrick Tembi Efie Sefirin Djiogue François F Kaze Yannick Mboue-Djieka Thadée Boudjeko Etienne Dongo Jean-François Gautier Andre-Pascal Kengne

Journal:

Content:

Hydroquinone-containing creams cause false increases in capillary glycemia. However, the magnitude of this false increase, and the means to reverse it have not been investigated.To evaluate the technical and clinical impact of hydroquinone-containing creams on capillary glycemia and investigate the efficacy of hand washing and other common practices, in reversing cream effects.We included 91 participants in a quasi-experimental study in Buea, Cameroon. After determining the hydroquinone content of a cream, Caro Light, we used two glucometers with different enzymatic systems (Accu-Chek Active and OneTouch Ultra 2) to measure fasting glycemia after: initial hand washing (reference), application of 1 ml of hydroquinone-containing cream, finger swabbing with wet gauze, sanitizer application and a series of three hand washings following cream application. Reference glycemia was compared to those obtained after various interventions. Statistical significance was assessed by paired sample t-test, clinical significance by total error allowable (TEa), and clinical impact by Parke's error grid analysis.The mean differences in capillary glycemia (Intervention-reference) measured by Accu-Chek Active in mg/dl were 28, 27, 38, 16, 4, and -2 after cream application, finger swabbing, sanitizer application, one, two, and three hand washings respectively. Corresponding values for OneTouch Ultra2 were 41, 44, 64, 22, 5 and -5. These differences, except after two and three hand washings were both statistically (p < 0.0001) and clinically significant (TEa). After cream application, Accu-Check had 9.9% of values in Parke's Zones C-E, while OneTouch had 18.7%.Hydroquinone-containing creams cause significant false increase in capillary glycemia irrespective of the enzymatic system of the glucometer used, and can lead to potentially wrong clinical decisions. A minimum of two hand washings is required prior to capillary glucose measurement.

Date:

Authors:

Matsha TE Kengne AP Hector S Mbu DL Yako YY Erasmus RT

Journal:

Oncotarget

Content:

Date:

2018-07-01

Authors:

Cecil J. Weale Don M. Matshazi Saarah F. G. Davids Shanel Raghubeer Rajiv T. Erasmus Andre P. Kengne Glenda M. Davison Tandi E. Matsha

Journal:

Diagnostics

Content:

Date:

2021-05-26

Authors:

Tandi Edith Matsha Katya Masconi Yandiswa Yolanda Yako Mogamat Shafick Hassan Muiriri Macharia Rajiv Timothy Erasmus Andre Pascal Kengne

Journal:

Content:

OBJECTIVE: Though single nucleotide polymorphisms (SNPs) in the non-muscle myosin gene (MYH9) have been reported to explain most of the excess risk of nondiabetic chronic kidney disease (CKD), in African-Americans, some studies have also shown associations with diabetic end-stage renal disease. We investigated the association of MYH9 SNPs with renal traits in a mixed-ancestry South African population prone to diabetes. RESEARCH DESIGN AND METHODS: Three SNPs known to be associated with CKD (rs4821480, rs5756152 and rs12107) were genotyped using Taqman assay in 716 adults (198 with diabetes) from the Bellville-South community, Cape Town. Glomerular filtration rate was estimated (eGFR) and urinary albumin/creatinine ratio (ACR) assessed. Multivariable regressions were used to relate the SNPs with renal traits. RESULTS: Mean age was 53.6 years, with the expected differences observed in characteristics by diabetic status. Significant associations were found between rs575152 and serum creatinine, and eGFR in the total population, and in diabetic participants (all p≤0.003), but not in non-diabetics (all p≥0.16), with significant interactions by diabetes status (interaction-p≤0.009). The association with ACR was borderline in diabetic participants (p = 0.05) and non-significant in non-diabetics (p = 0.85), with significant interaction (interaction p = 0.02). rs12107 was associated with fasting-, 2-hour glucose and HbA1c in diabetic participants only (interaction-p≤0.003), but not with renal traits. CONCLUSION: MYH9 SNPs were associated with renal traits only in diabetic participants in this population. Our findings and other studies suggest that MYH9 may have a broader genetic risk effect on kidney diseases.

Date:

Authors:

Peer N de Villiers A Jonathan D Kalombo C Kengne AP.

Journal:

Content:

Date:

2020-01-01

Authors:

Negash S Agyemang C Matsha TE Peer N Erasmus RT Kengne AP

Journal:

BMC obesity

Content:

Date:

2017-07-01

Authors:

Andre Pascal, Kengne

Journal:

Content:

Date:

2013-01-01

Authors:

Echouffo-Tcheugui JB Kengne AP Erqou S Cooper RS

Journal:

Journal of clinical hypertension (Greenwich, Conn.)

Content:

Date:

2015-07-01

Authors:

Matshazi DM Weale CJ Erasmus RT Kengne AP Davids SFG Raghubeer S Hector S Davison GM Matsha TE

Journal:

Frontiers in cardiovascular medicine

Content:

Date:

2021-04-01

Authors:

Mazidi M Rezaie P Gao HK Kengne AP

Journal:

Journal of the American Heart Association

Content:

Date:

2017-05-01

Authors:

Ng M Fleming T Robinson M Thomson B Graetz N Margono C Mullany EC Biryukov S Abbafati C Abera SF Abraham JP Abu-Rmeileh NM Achoki T Gakidou E

Journal:

Lancet (London, England)

Content:

Date:

2014-05-01

Authors:

Local Burden of Disease Diarrhoea Collaborators

Journal:

The Lancet. Global health

Content:

Date:

2020-08-01

Authors:

Mazidi M Banach M Kengne AP

Journal:

European journal of clinical nutrition

Content:

Date:

2018-03-01

Authors:

Kanmogne GD Fonsah JY Umlauf A Moul J Doh RF Kengne AM Tang B Tagny CT Nchindap E Kenmogne L Franklin D Njamnshi DM Mbanya D Njamnshi AK Heaton RK

Journal:

Journal of the International Neuropsychological Society : JINS

Content:

Date:

2020-02-01

Authors:

Kim Anh Nguyen Nasheeta Peer Anniza de Villiers Barbara Mukasa Tandi E. Matsha Edward J. Mills Andre Pascal Kengne

Journal:

Content:

The distribution of body size phenotypes in people with human immunodeficiency virus (HIV) infection has yet to be characterized. We assessed the distribution of body size phenotypes overall, and according to antiretroviral therapy (ART), diagnosed duration of the infection and CD4 count in a sample of HIV infected people recruited across primary care facilities in the Western Cape Province, South Africa. Adults aged ≥ 18 years were consecutively recruited using random sampling procedures, and their cardio-metabolic profile were assessed during March 2014 and February 2015. They were classified across body mass index (BMI) categories as normal-weight (BMI < 25 kg/m2), overweight (25 ≤ BMI < 30 kg/m2), and obese (BMI ≥ 30 kg/m2), and further classified according to their metabolic status as “metabolically healthy” vs. “metabolically abnormal” if they had less than two vs. two or more of the following abnormalities: high blood glucose, raised blood pressure, raised triglycerides, and low HDL-cholesterol. Their cross-classification gave the following six phenotypes: normal-weight metabolically healthy (NWMH), normal-weight metabolically abnormal (NWMA), overweight metabolically healthy (OvMH), overweight metabolically abnormal (OvMA), obese metabolically healthy (OMH), and obese metabolically abnormal (OMA). Among the 748 participants included (median age 38 years (25th–75th percentiles: 32–44)), 79% were women. The median diagnosed duration of HIV was five years; the median CD4 count was 392 cells/mm3 and most participants were on ART. The overall distribution of body size phenotypes was the following: 31.7% (NWMH), 11.7% (NWMA), 13.4% (OvMH), 9.5% (OvMA), 18.6% (OMH), and 15.1% (OMA). The distribution of metabolic phenotypes across BMI levels did not differ significantly in men vs. women (p = 0.062), in participants below vs. those at or above median diagnosed duration of HIV infection (p = 0.897), in participants below vs. those at or above median CD4 count (p = 0.447), and by ART regimens (p = 0.205). In this relatively young sample of HIV-infected individuals, metabolically abnormal phenotypes are frequent across BMI categories. This highlights the importance of general measures targeting an overall improvement in cardiometabolic risk profile across the spectrum of BMI distribution in all adults with HIV.

Date:

2016-01-01

Authors:

Hamer M Bruwer EJ de Ridder JH Swanepoel M Kengne AP Cockeran M Malan L

Journal:

Journal of human hypertension

Content:

Date:

2017-01-01

Authors:

Carrillo-Larco RM Miranda JJ Kengne AP

Journal:

The Lancet. Global health

Content:

Date:

2017-01-01

Authors:

Veitenhansl M Stegner K Hierl FX Dieterle C Feldmeier H Gutt B Landgraf R Garrow AP Vileikyte L Findlow A Waterman C Boulton AJ Sekihara H

Journal:

Diabetologia

Content:

Date:

2004-08-01

Authors:

Naeemah Abrahams Shibe Mhlongo Esnat Chirwa Carl Lombard Kristin Dunkle Soraya Seedat Andre Pascal Kengne Bronwyn Myers Nasheeta Peer Claudia M. García-Moreno Rachel Jewkes

Journal:

Global Health Action

Content:

Date:

2020-12-31

Authors:

Kanmogne GD Qiu F Ntone FE Fonsah JY Njamnshi DM Kuate CT Doh RF Kengne AM Tagny CT Nchindap E Kenmogne L Mbanya D Cherner M Heaton RK Njamnshi AK

Journal:

PloS one

Content:

Date:

2017-02-01

Authors:

Hill J Peer N Oldenburg B Kengne AP

Journal:

PloS one

Content:

Date:

2017-12-01

Authors:

Dzudie A Djomou A Ba H Njume E Ndom MS Mfekeu LK Ndongo S Kouam CK Awungia A Ze S Menanga A Kengne AP Xia X Beaney T Poulter NR Cameroon Cardiac Society and MMM Cameroon Investigator Group

Journal:

European heart journal supplements : journal of the European Society of Cardiology

Content:

Date:

2019-04-01

Authors:

Journal:

International journal of epidemiology

Content:

BACKGROUND: This study aimed to assess the association between lifetime exposure to urban environment (EU) and obesity, diabetes, and hypertension in an adult population of Sub-Saharan Africa. METHODS: We studied 999 women and 727 men aged > or =25 years. They represent all the adults aged > or =25 years living in households randomly selected from a rural and an urban community of Cameroon with a 98% and 96% participation rate respectively. Height, weight, blood pressure, and fasting blood glucose were measured in all subjects. Current levels of physical activity (in metabolic equivalents [MET]) were evaluated through the Sub-Saharan African Activity Questionnaire. Chronological data on lifetime migration were collected retrospectively and expressed as the total (EUt) or percentage (EU%) of lifetime exposure to urban environment. RESULTS: Lifetime EUt was associated with body mass index (BMI) (r = 0.42; P < 0.0001), fasting glycaemia (r = 0.23; P < 0.0001), and blood pressure (r = 0.17; P < 0.0001) but not with age. The subjects who recently settled in a city (< or =2 years) had higher BMI (+2.9 kg/m(2); P < 0.001), fasting glycaemia (+0.8 mmol/l; P < 0.001), systolic (+23 mmHg; P < 0.001) and diastolic (+9 mmHg; P = 0.001) blood pressure than rural dwellers with a history of 2 years EU. EU during the first 5 years of life was not, on its own, associated with glycaemia or BMI. However, both lifetime EUt and current residence were independently associated with obesity and diabetes. The association between lifetime EUt and hypertension was not independent of current residence and current level of physical activity. CONCLUSIONS: This study suggests that for the study of obesity and diabetes, in addition to current residence, both lifetime exposure to an urban environment and recent migration history should be investigated.

Date:

2004-05-27

Authors:

Macharia M Kengne AP Blackhurst DM Erasmus RT Hoffmann M Matsha TE

Journal:

Oxidative medicine and cellular longevity

Content:

Date:

2014-03-01

Authors:

Andre Pascal Kengne Tandi E. Matsha David B. Sacks Annalise E. Zemlin Rajiv T Erasmus Anne E. Sumner

Journal:

eClinicalMedicine

Content:

Date:

2022-05-01

Authors:

Simeon-Pierre Choukem André-Pascal Kengne Maxime-Leolein Nguefack Yannick Mboue-Djieka Daniel Nebongo Jackson T Guimezap Jean Claude Mbanya

Journal:

Content:

Abstract Background Obesity is a major risk factor for non-communicable diseases (NCDs) and is growing rapidly globally including in sub-Saharan Africa (SSA). We aimed to assess the trend in adiposity markers in Cameroonian university students, and investigated their associations with hypertension. Methods From 2009 to 2012, we annually measured weight, height, blood pressure, waist (WC) and hip circumferences, and calculated the body mass index (BMI) and other indices of adiposity in consecutive students aged 18 years or above, during their registration. Time-trends in prevalence of overweight and obesity were estimated, and their associations with prevalent hypertension investigated. Results Among the 2726 participants, the overall prevalence of obesity, overweight and obesity combined, and hypertension was 3.5%, 21.0% and 6.3% respectively. From 2009 to 2012, the prevalence of overweight and obesity increased in men only, from 13.1% to 20.9% (p-trend = 0.002), whereas prevalent abdominal obesity increased in women only, from 6.5% to 11.7% (p-trend = 0.027). The BMI and the WC were independent predictors of hypertension; each kg/m2 higher BMI was associated with 11% higher odds of hypertension, and each centimeter higher WC was associated with 9% higher odds of hypertension. Conclusion Our results show that overweight and obesity are rapidly increasing in this population of young sub-Saharan African adults, and are contributing to an increasing burden of hypertension.

Date:

2017-01-01

Authors:

Anastase Dzudie Tamdja Simeon Pierre Choukem Abdoul Khadir Adam Andre Pascal Kengne Mesmin Dehayem Yves Monkam Mbouende Felicite Kamdem Marie Solange Doualla Henry Luma

Journal:

Archives of Cardiovascular Diseases Supplements

Content:

Date:

2012-01-01

Authors:

Matsha TE Soita DJ Hassan MS Hon GM Yako YY Kengne AP Erasmus RT

Journal:

Diabetes research and clinical practice

Content:

Date:

2012-11-01

Authors:

GBD 2015 Maternal Mortality Collaborators

Journal:

Lancet (London, England)

Content:

Date:

2016-10-01

Authors:

van Hoving DJ Meintjes G Maartens G Kengne AP

Journal:

Content:

Date:

2020-04-01

Authors:

Mazidi M Gao HK Vatanparast H Kengne AP

Journal:

Medicine

Content:

Date:

2017-02-01

Authors:

Theodosia Adom André Pascal Kengne Anniza De Villiers Thandi Puoane

Journal:

Content:

Abstract Background Little is known about the impact of the school environmental context on the emerging trend of childhood obesity in Africa. We examined the association of the schools’ contextual factors with body mass index (BMI), abdominal obesity and overweight (including obesity) in urban Ghana. Method Using cross-sectional data from 543 school children aged 8–11 years attending 14 primary schools, we applied multilevel logistic regressions and linear regression models to investigate the association of child- and school level attributes with overweight, abdominal obesity, and BMI. Results We observed significant variance of the random effects of schools in BMI (2.65, p < 0.05), abdominal obesity (0.85, p < 0.05), and overweight (1.41, p < 0.05), with school contextual levels accounting for 19.7, 20.6, and 30.0% of the total variability observed in BMI, abdominal obesity and overweight respectively. Attending high socioeconomic (SES) level school, private school and school with increased after-school recreational facilities were associated with higher BMI. Children were more likely to be overweight if they attended a high SES level school, had access to healthful foods at school, and after-school recreational facilities. With regards to abdominal obesity, attending a school with increased physical activity facilities decreased the odds of abdominal obesity; however the odds increased if they attended a school with access to after-school recreational facilities. Conclusion A number of school-level factors were associated with BMI, overweight and abdominal obesity of children in the present study. Our results provide support for improved school environment to reduce overweight.

Date:

2019-01-01

Authors:

Nansseu JR Fokom-Domgue J Noubiap JJ Balti EV Sobngwi E Kengne AP

Journal:

BMJ open

Content:

Date:

2015-05-01

Authors:

Yandiswa Y. Yako Eric V. Balti Tandi E. Matsha Anastase Dzudie Deirdre Kruger Eugene Sobngwi Charles Agyemang Andre P. Kengne

Journal:

The Journal of Clinical Hypertension

Content:

Date:

2018-03-09

Authors:

Caleyachetty R Tait CA Kengne AP Corvalan C Uauy R Echouffo-Tcheugui JB

Journal:

The Lancet. Global health

Content:

Date:

2014-08-01

Authors:

Ama V Kengne AP Nansseu NJ Nouthe B Sobngwi E

Journal:

Diabetic medicine : a journal of the British Diabetic Association

Content:

Date:

2012-09-01

Authors:

Yone ÉW Kuaban C Kengne AP

Journal:

Revue de pneumologie clinique

Content:

Date:

2012-11-01

Authors:

Echouffo-Tcheugui JB Kengne AP

Journal:

PLoS medicine

Content:

Date:

2012-11-01

Authors:

George C Yako YY Okpechi IG Matsha TE Kaze Folefack FJ Kengne AP

Journal:

BMC medical genetics

Content:

Date:

2018-10-01

Authors:

NCD Risk Factor Collaboration (NCD-RisC)

Journal:

Lancet (London, England)

Content:

Date:

2020-11-01

Authors:

Erqou S Lodebo BT Masri A Altibi AM Echouffo-Tcheugui JB Dzudie A Ataklte F Choudhary G Bloomfield GS Wu WC Kengne AP

Journal:

JACC. Heart failure

Content:

Date:

2019-02-01

Authors:

Yako YY Echouffo-Tcheugui JB Balti EV Matsha TE Sobngwi E Erasmus RT Kengne AP

Journal:

Obesity reviews : an official journal of the International Association for the Study of Obesity

Content:

Date:

2015-02-01

Authors:

Kengne AP Mayosi BM

Journal:

Cardiovascular journal of Africa

Content:

Date:

2012-09-01

Authors:

Vergotine Z Kengne AP Erasmus RT Matsha TE

Journal:

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde

Content:

Date:

2014-05-01

Authors:

Ekrikpo UE Mnika K Effa EE Ajayi SO Okwuonu C Waziri B Bello A Dandara C Kengne AP Wonkam A Okpechi I

Journal:

American journal of kidney diseases : the official journal of the National Kidney Foundation

Content:

Date:

2020-04-01

Authors:

Eric Walter Pefura Yone André Pascal Kengne Gloria Ashuntantang Awa Foueudjeu Betyoumin Jeanne Ngogang To Pefura Yone Ew Kengne Ap Ashuntantang G Prepublication History Licence See

Journal:

Content:

patients receiving protease inhibitors after initial treatment with first-line-based non-nucleoside reverse transcriptase inhibitors: a cross-sectional study

Date:

Authors:

GBD 2015 Eastern Mediterranean Region Adolescent Health Collaborators

Journal:

International journal of public health

Content:

Date:

2017-08-01

Authors:

Malambo P De Villiers A Lambert EV Puoane T Kengne AP

Journal:

BMC public health

Content:

Date:

2018-07-01

Authors:

Echouffo-Tcheugui JB Kengne AP

Journal:

Primary care diabetes

Content:

Date:

2013-04-01

Authors:

Sobngwi E Mfeukeu-Kuate L Kouam M Tankeu AT Nganou-Gnindjio CN Hamadou B Etoa M Ngassam E Nkamgna A Dehayem MY Kaze FF Kengne AP Mbanya JC

Journal:

Journal of clinical hypertension (Greenwich, Conn.)

Content:

Date:

2019-06-01

Authors:

Zemlin AE Barkhuizen M Kengne AP Erasmus RT Matsha TE

Journal:

Clinica chimica acta; international journal of clinical chemistry

Content:

Date:

2018-11-01

Authors:

Malambo P Kengne AP Lambert EV De Villiers A Puoane T

Journal:

Archives of public health = Archives belges de sante publique

Content:

Date:

2016-12-01

Authors:

Mazidi M Kengne AP Katsiki N Mikhailidis DP Banach M

Journal:

The British journal of nutrition

Content:

Date:

2018-10-01

Authors:

GBD 2017 Population and Fertility Collaborators

Journal:

Lancet (London, England)

Content:

Date:

2018-11-01

Authors:

Peer N Kengne AP

Journal:

Addiction (Abingdon, England)

Content:

Date:

2018-04-01

Authors:

GBD 2015 Healthcare Access and Quality Collaborators. Electronic address: cjlm@uw.edu GBD 2015 Healthcare Access and Quality Collaborators

Journal:

Lancet (London, England)

Content:

Date:

2017-05-01

Authors:

Fokom-Domgue J Combescure C Fokom-Defo V Tebeu PM Vassilakos P Kengne AP Petignat P

Journal:

BMJ (Clinical research ed.)

Content:

Date:

2015-07-01

Authors:

Caleyachetty R Meunnig P Kengne AP

Journal:

International journal of obesity (2005)

Content:

Date:

2016-04-01

Authors:

Fezeu L Balkau B Sobngwi E Kengne AP Vol S Ducimetiere P Mbanya JC

Journal:

International journal of obesity (2005)

Content:

Date:

2010-01-01

Authors:

Eric Vounsia Balti André Pascal Kengne Jean Valentin Fogha Fokouo Brice Enid Nouthé Eugene Sobngwi

Journal:

Content:

Date:

Authors:

WHO CVD Risk Chart Working Group

Journal:

The Lancet. Global health

Content:

Date:

2019-09-01

Authors:

Kengne AP Dehayem M Choukem SP Awah P Mbanya JC

Journal:

Cardiovascular journal of Africa

Content:

Date:

2007-07-01

Authors:

Carla Cruvinel Pontes Usuf Chikte Faheema Kimmie-Dhansay Rajiv T. Erasmus Andre P. Kengne Tandi E. Matsha

Journal:

International Journal of Environmental Research and Public Health

Content:

Date:

2020-02-07

Authors:

Dzudie A Barche B Mouliom S Nouko A Raissa F Njebet J Sarah A Abah J Djomou A Nzali A Nkoke C Kamdem F Kingue S Sliwa K Kengne AP

Journal:

Content:

Date:

2020-11-01

Authors:

Kengne AP Sobngwi E Fezeu L Awah PK Dongmo S Mbanya JC CENHIP * Investigators

Journal:

The Pan African medical journal

Content:

Date:

2009-10-01

Authors:

Dobrokhotov V Oakes L Sowell D Larin A Hall J Barzilov A Kengne A Bakharev P Corti G Cantrell T Prakash T Williams J Bergman L Huso J McIlroy D

Journal:

Sensors (Basel, Switzerland)

Content:

Date:

2012-05-01

Authors:

Sabeel S Motaung B Ozturk M Mukasa S Kengne AP Blom D Sliwa K Nepolo E Günther G Wilkinson RJ Schacht C Thienemann F Guler R

Journal:

BMJ open

Content:

Date:

2020-08-01

Authors:

Dzudie A Dzekem BS Kengne AP

Journal:

Cardiovascular journal of Africa

Content:

Date:

2017-11-01

Authors:

Kengne AP Echouffo-Tcheugui JB

Journal:

The Lancet. Global health

Content:

Date:

2019-08-01

Authors:

Pefura Yone EW Kengne AP Ashuntantang G Betyoumin AF Ngogang J

Journal:

BMJ open

Content:

Date:

2012-08-01

Authors:

Lekoubou A Nkoke C Dzudie A Kengne AP

Journal:

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association

Content:

Date:

2017-04-01

Authors:

Baatiema L Abimbola S de-Graft Aikins A Damasceno A Kengne AP Sarfo FS Charway-Felli A Somerset S

Journal:

Journal of the neurological sciences

Content:

Date:

2020-09-01

Authors:

Mazidi M Gao HK Kengne AP

Journal:

Medicine

Content:

Date:

2018-05-01

Authors:

Mazidi M Kengne AP Mikhailidis DP Cicero AF Banach M

Journal:

Annals of medicine

Content:

Date:

2017-05-01

Authors:

Cecil Jack Weale Don M Matshazi Saarah FG Davids Shanel Raghubeer Rajiv T Erasmus Andre Pascal Kengne Glenda Mary Davison Tandi E Matsha

Journal:

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy

Content:

Date:

2020-12-01

Authors:

T. Adom A. P. Kengne A. De Villiers T. Puoane

Journal:

Obesity Science & Practice

Content:

Date:

2019-10-20

Authors:

Nasheeta Peer Leonard Baatiema Andre-Pascal Kengne

Journal:

Expert Review of Cardiovascular Therapy

Content:

Date:

2021-02-01

Authors:

Malambo P De Villiers A Lambert EV Puoane T Kengne AP

Journal:

PloS one

Content:

Date:

2018-10-01

Authors:

Aminde LN Atem JA Kengne AP Dzudie A Veerman JL

Journal:

BMC obesity

Content:

Date:

2017-01-01

Authors:

Echouffo-Tcheugui JB Mayige M Ogbera AO Sobngwi E Kengne AP

Journal:

Diabetes research and clinical practice

Content:

Date:

2012-09-01

Authors:

Stephen S., Lim Kate, Allen Zulfi qar A., Bhutta Lalit, Dandona Mohammad H., Forouzanfar Nancy, Fullman Peter W., Gething Ellen M., Goldberg Simon I., Hay Mollie, Holmberg Yohannes, Kinfu Michael J., Kutz Heidi J., Larson Xiaofeng, Liang Alan D., Lopez Rafael, Lozano Claire R., Mcnellan Ali H., Mokdad Meghan D., Mooney Mohsen, Naghavi Helen E., Olsen David M., Pigott Joshua A., Salomon Theo, Vos Haidong, Wang Amanuel Alemu, Abajobir Kalkidan Hassen, Abate Cristiana, Abbafati Kaja M., Abbas Foad Abd, Allah Abdishakur M., Abdulle Biju, Abraham Ibrahim, Abubakar Laith J., Abu Raddad Niveen M. E., Abu Rmeileh Gebre Yitayih, Abyu Tom, Achoki Akindele Olupelumi, Adebiyi Isaac Akinkunmi, Adedeji Kossivi Agbelenko, Afanvi Ashkan, Afshin Arnav, Agarwal Anurag, Agrawal Aliasghar Ahmad, Kiadaliri Hamid, Ahmadieh Kedir Yimam, Ahmed Ali Shafqat, Akanda Rufus Olusola, Akinyemi Tomi F., Akinyemiju Nadia, Akseer Ziyad Al, Aly Khurshid, Alam Uzma, Alam Deena, Alasfoor Fadia S., Albuhairan Saleh Fahed, Aldhahri Robert William, Aldridge Zewdie Aderaw, Alemu Raghib, Ali Ala’A, Alkerwi Mohammad AB, Alkhateeb François, Alla Peter, Allebeck Christine, Allen Rajaa Al, Raddadi Khalid A., Altirkawi Elena Alvarez, Martin Nelson Alvis, Guzman Azmeraw T., Amare Alemayehu, Amberbir Adeladza Kofi, Amegah Heresh, Amini Walid, Ammar Stephen Marc, Amrock Hjalte H., Andersen Benjamin O., Anderson Gregory M., Anderson Carl Abelardo T., Antonio Palwasha, Anwari Johan, Ärnlöv Al, Artaman Hamid, Asayesh Rana Jawad, Asghar Suleman, Atique Euripide Frinel G., Arthur Avokpaho Ashish, Awasthi Beatriz Paulina Ayala, Quintanilla Peter, Azzopardi Umar, Bacha Alaa, Badawi Kalpana, Balakrishnan Amitava, Banerjee Aleksandra, Barac Ryan, Barber Suzanne L., Barker Collo Till, Bärnighausen Lope H., Barrero Tonatiuh Barrientos, Gutierrez Sanjay, Basu Tigist Assefa, Bayou Shahrzad Bazargan, Hejazi Justin, Beardsley Neeraj, Bedi Ettore, Beghi Yannick, Béjot Michelle L., Bell Aminu K., Bello Derrick A., Bennett Isabela M., Bensenor Habib, Benzian Adugnaw, Berhane Eduardo, Bernabé Oscar Alberto, Bernal Balem Demtsu, Betsu Addisu Shunu, Beyene Neeraj, Bhala Samir, Bhatt Sibhatu, Biadgilign Kelly A., Bienhoff Boris, Bikbov Agnes, Binagwaho Donal, Bisanzio Espen, Bjertness Jed, Blore Rupert R. A., Bourne Michael, Brainin Michael, Brauer Alexandra, Brazinova Nicholas J. K., Breitborde David M., Broday Traolach S., Brugha Rachelle, Buchbinder Zahid A., Butt Leah E., Cahill Ismael Ricardo Campos, Nonato Julio Cesar, Campuzano Hélène, Carabin Rosario, Cárdenas Juan Jesus, Carrero Austin, Carter Daniel, Casey Valeria, Caso Carlos A., Castañeda Orjuela Jacqueline Castillo, Rivas Ferrán Catalá, López Fiorella, Cavalleri Pedro, Cecílio Hsing Yi, Chang Jung Chen, Chang Fiona J., Charlson Xuan, Che Alan Zian, Chen Peggy Pei Chia, Chiang Mirriam, Chibalabala Vesper Hichilombwe, Chisumpa Jee Young Jasmine, Choi Rajiv, Chowdhury Hanne, Christensen Liliana G., Ciobanu Cirillo, Massimo Matthew M., Coates Megan, Coggeshall Aaron J., Cohen Graham S., Cooke Cyrus, Cooper Leslie Trumbull, Cooper Benjamin C., Cowie John A., Crump Solomon Abrha, Damtew Rakhi, Dandona Paul I., Dargan José das, Neves Adrian C., Davis Kairat, Davletov E., Filipa de Castro Diego De, Leo Louisa, Degenhardt Liana C., Del Gobbo Kebede, Deribe Sarah, Derrett Don C., Des Jarlais Aniruddha, Deshpande Gabrielle A., Deveber Subhojit, Dey Samath D., Dharmaratne Preet K., Dhillon Eric L., Ding E., Ray Dorsey Kerrie E., Doyle Tim R., Driscoll Leilei, Duan Manisha, Dubey Bruce Bartholow, Duncan Hedyeh, Ebrahimi Aman Yesuf, Endries Sergey Petrovich, Ermakov Holly E., Erskine Babak, Eshrati Alireza, Esteghamati Saman, Fahimi Talha A., Farid Carla Sofi a. e., Sa Farinha André, Faro Maryam S., Farvid Farshad, Farzadfar Valery L., Feigin Manuela Mendonca, Felicio Seyed Mohammad, Fereshtehnejad Jefferson G., Fernandes Joao C., Fernandes Alize J., Ferrari Florian, Fischer Joseph R. A., Fitchett Christina, Fitzmaurice Nataliya, Foigt Kyle, Foreman F. Gerry R., Fowkes Elisabeth Barboza, Franca Richard C., Franklin Maya, Fraser Joseph, Friedman Joseph, Frostad Thomas, Fürst Belinda, Gabbe Alberto L., Garcia Basteiro Teshome, Gebre Tsegaye Tewelde, Gebrehiwot Amanuel Tesfay, Gebremedhin Alemseged Aregay, Gebru Bradford D., Gessner Richard F., Gillum Ibrahim Abdelmageem Mohamed, Ginawi Ababi Zergaw, Giref Maurice, Giroud Melkamu Dedefo, Gishu William, Godwin Philimon, Gona Amador, Goodridge Sameer Vali, Gopalani Carolyn C., Gotay Atsushi, Goto Hebe N., Gouda Nicholas, Graetz Karen Fern, Greenwell Max, Griswold Yuming, Guo Rahul, Gupta Rajeev, Gupta Vipin, Gupta Reyna A., Gutiérrez Bishal, Gyawali Juanita A., Haagsma Annie, Haakenstad Nima Hafezi, Nejad Demewoz, Haile Gessessew Bugssa, Hailu Yara A., Halasa Randah Ribhi, Hamadeh Samer, Hamidi Mouhanad, Hammami Graeme J., Hankey Hilda L., Harb Josep Maria, Haro Mohammad Sadegh, Hassanvand Rasmus, Havmoeller Ileana Beatriz Heredia, Pi Hans W., Hoek Masako, Horino Nobuyuki, Horita H., Dean Hosgood Damian G., Hoy Aung Soe, Htet Guoqing, Hu Hsiang, Huang Kim Moesgaard, Iburg Bulat T., Idrisov Manami, Inoue Farhad, Islami Troy A., Jacobs Kathryn H., Jacobsen Nader, Jahanmehr Mihajlo B., Jakovljevic Peter, James Henrica A. F. M., Jansen Mehdi, Javanbakht Achala Upendra, Jayatilleke Sun Ha, Jee Panniyammakal, Jeemon Vivekanand, Jha Ying, Jiang Tariku, Jibat Ye, Jin Jost B., Jonas Zubair, Kabir Yogeshwar, Kalkonde Ritul, Kamal Haidong, Kan Amit, Kandel André, Karch Corine Kakizi, Karema Chante, Karimkhani Palitha, Karunapema Amir, Kasaeian Nicholas J., Kassebaum Anil, Kaul Norito, Kawakami Jeanne Françoise, Kayibanda Peter Njenga, Keiyoro Laura, Kemmer Andrew Haddon, Kemp Andre Pascal, Kengne Andre, Keren Chandrasekharan Nair, Kesavachandran Yousef Saleh, Khader Abdur Rahman, Khan Ejaz Ahmad, Khan Gulfaraz, Khan Young Ho, Khang Tawfi k., Ahmed Muthafer Khoja Ardeshir, Khosravi Jagdish, Khubchandani Christian, Kieling Cho il, Kim Daniel, Kim Sungroul, Kim Yun Jin, Kim Ruth W., Kimokoti Niranjan, Kissoon Miia, Kivipelto Luke D., Knibbs Yoshihiro, Kokubo Dhaval, Kolte Soewarta, Kosen Georgios A., Kotsakis Parvaiz A., Koul Ai, Koyanagi Michael, Kravchenko Hans, Krueger Barthelemy Kuate, Defo Ricardo S., Kuchenbecker Ernst J., Kuipers Xie Rachel, Kulikoff Veena S., Kulkarni G., Anil Kumar Gene F., Kwan Hmwe H., Kyu Aparna, Lal Dharmesh Kumar, Lal Ratilal, Lalloo Hilton, Lam Qing, Lan Sinead M., Langan Anders, Larsson Dennis Odai, Laryea Asma Abdul, Latif Janet L., Leasher James, Leigh Mall, Leinsalu Janni, Leung Ricky, Leung Miriam, Levi Yichong, Li Yongmei, Li Margaret, Lind Shai, Linn Steven E., Lipshultz Patrick Y., Liu Shiwei, Liu Yang, Liu Belinda K., Lloyd Loon Tzian, Lo Giancarlo, Logroscino Paulo A., Lotufo Robyn M., Lucas Raimundas, Lunevicius Mohammed Magdy Abd El, Razek Carlos Magis, Rodriguez Mahdi, Mahdavi Marek, Majdan Azeem, Majeed Reza, Malekzadeh Deborah Carvalho, Malta Chabila C., Mapoma David Joel, Margolis Randall V., Martin Jose Martinez, Raga Felix, Masiye Amanda J., Mason Jones João, Massano Richard, Matzopoulos Bongani M., Mayosi John J., Mcgrath Martin, Mckee Peter A., Meaney Alem, Mehari Alemayehu B., Mekonnen Yohannes Adama, Melaku Peter, Memiah Ziad A., Memish Walter, Mendoza Gert B. M., Mensink Atte, Meretoja Tuomo J., Meretoja Yonatan Moges Mesfi, N Francis Apolinary, Mhimbira Renata, Micha Ted R., Miller Edward J., Mills Mojde Mirarefi, N Awoke, Misganaw Philip B., Mitchell Charles N., Mock Alireza, Mohammadi Shafi u., Mohammed Lorenzo, Monasta Jonathan de la Cruz, Monis Julio Cesar Montañez, Hernandez Marcella, Montico Maziar Moradi, Lakeh Lidia, Morawska Rintaro, Mori Ulrich O., Mueller Michele E., Murdoch Brighton, Murimira Joseph, Murray Gudlavalleti Venkata Satyanarayana, Murthy Srinivas, Murthy Kamarul Imran, Musa Jean B., Nachega Gabriele, Nagel Kovin S., Naidoo Luigi, Naldi Vinay, Nangia Bruce, Neal Chakib, Nejjari Charles R., Newton John N., Newton Frida Namnyak, Ngalesoni Peter, Nguhiu Grant, Nguyen Quyen Le, Nguyen Muhammad Imran, Nisar Patrick Martial Nkamedjie, Pete Sandra, Nolte Marika, Nomura Ole F., Norheim Bo, Norrving Carla Makhlouf, Obermeyer Felix Akpojene, Ogbo In Hwan, Oh Olanrewaju, Oladimeji Pedro R., Olivares Bolajoko Olubukunola, Olusanya Jacob Olusegun, Olusanya John Nelson, Opio Eyal, Oren Alberto, Ortiz Richard H., Osborne Erika, Ota Mayowa O., Owolabi Mahesh, Pa Eun Kee, Park Hye Youn, Park Charles D., Parry Mahboubeh, Parsaeian Tejas, Patel Vikram, Patel Angel J., Paternina Caicedo Snehal T., Patil Scott B., Patten George C., Patton Deepak, Paudel João Mário, Pedro David M., Pereira Norberto, Perico Konrad, Pesudovs Max, Petzold Michael Robert, Phillips Frédéric B., Piel Julian David, Pillay Christine, Pinho Farhad, Pishgar Suzanne, Polinder Richie G., Poulton Farshad, Pourmalek Mostafa, Qorbani Rynaz H. S., Rabiee Amir, Radfar Vafa Rahimi, Movaghar Mahfuzar, Rahman Mohammad Hifz Ur, Rahman Sajjad Ur, Rahman Rajesh Kumar, Rai Sasa, Rajsic Murugesan, Raju Usha, Ram Saleem M., Rana Chhabi Lal, Ranabhat Kavitha, Ranganathan Puja C., Rao Amany H., Refaat Marissa B., Reitsma Giuseppe, Remuzzi Serge, Resnikoff Antonio L., Ribeiro Maria Jesus Rios, Blancas Hirbo Shore, Roba Bayard, Roberts Alina, Rodriguez David Rojas, Rueda Luca, Ronfani Gholamreza, Roshandel Gregory A., Roth Dietrich, Rothenbacher Ambuj, Roy Nobhojit, Roy Ben Benasco, Sackey Rajesh, Sagar Muhammad Muhammad, Saleh Juan R., Sanabria Damian F., Santomauro Itamar S., Santos Rodrigo Sarmiento, Suarez Benn, Sartorius Maheswar, Satpathy Miloje, Savic Monika, Sawhney Susan M., Sawyer Josef, Schmidhuber Maria Inês, Schmidt Ione J. C., Schneider Aletta E., Schutte David C., Schwebel Soraya, Seedat Sadaf G., Sepanlou Edson E., Servan Mori Katya, Shackelford Amira, Shaheen Masood Ali, Shaikh Teresa Shamah, Levy Rajesh, Sharma Jun, She Sara, Sheikhbahaei Jiabin, Shen Kevin N., Sheth Muki, Shey Peilin, Shi Kenji, Shibuya Mika, Shigematsu Min Jeong, Shin Rahman, Shiri Kawkab, Shishani Ivy, Shiue Inga Dora, Sigfusdottir Naris, Silpakit Diego Augusto Santos, Silva Jonathan I., Silverberg Edgar P., Simard Shireen, Sindi Abhishek, Singh Gitanjali M., Singh Jasvinder A., Singh Om Prakash, Singh Prashant Kumar, Singh Vegard, Skirbekk Amber, Sligar Samir, Soneji Kjetil, Søreide Reed J. D., Sorensen Joan B., Soriano Sergey, Soshnikov Luciano A., Sposato Chandrashekhar T., Sreeramareddy Hans Christian, Stahl Jeff rey D., Stanaway Vasiliki, Stathopoulou Nadine, Steckling Nicholas, Steel Dan J., Stein Caitlyn, Steiner Heidi, Stöckl Saverio, Stranges Mark, Strong Jiandong, Sun Bruno F., Sunguya Patrick, Sur Soumya, Swaminathan Bryan L., Sykes Cassandra E. I., Szoeke Rafael Tabarés, Seisdedos Karen M., Tabb Roberto Tchio, Talongwa Mohammed Rasoul, Tarawneh Mohammad, Tavakkoli Bineyam, Taye Hugh R., Taylor Bemnet Amare, Tedla Worku, Tefera Teketo Kassaw, Tegegne Dejen Yemane, Tekle Girma Temam, Shifa Abdullah Sulieman, Terkawi Gizachew Assefa, Tessema J. S., Thakur Alan J., Thomson Andrew L., Thorne Lyman Amanda G., Thrift George D., Thurston Taavi, Tillmann Ruoyan Tobe, Gai Marcello, Tonelli Roman Topor, Madry Fotis, Topouzis Bach Xuan, Tran Zacharie Tsala, Dimbuene Abera Kenay, Tura Emin Murat, Tuzcu Stefanos, Tyrovolas Kingsley Nnanna, Ukwaja Eduardo A., Undurraga Chigozie Jesse, Uneke Olalekan A., Uthman Aaron van, Donkelaar Yuri Y., Varakin Tommi, Vasankari Ana Maria Nogales, Vasconcelos J., Lennert Veerman Narayanaswamy, Venketasubramanian Raj Kumar, Verma Francesco S., Violante Vasiliy Victorovich, Vlassov Patricia, Volkow Stein Emil, Vollset Gregory R., Wagner Mitchell T., Wallin Linhong, Wang Valentine, Wanga David A., Watkins Scott, Weichenthal Elisabete, Weiderpass Robert G., Weintraub Daniel J., Weiss Andrea, Werdecker Ronny, Westerman Harvey A., Whiteford James D., Wilkinson Charles Shey, Wiysonge Charles D. A., Wolfe Ingrid, Wolfe Sungho, Won Anthony D., Woolf Shimelash Bitew, Workie Mamo, Wubshet Gelin, Xu Ajit Kumar, Yadav Bereket, Yakob Ayalnesh Zemene, Yalew Lijing L., Yan Yuichiro, Yano Mehdi, Yaseri Pengpeng, Ye Paul, Yip Naohiro, Yonemoto Seok Jun, Yoon Mustafa Z., Younis Chuanhua, Yu Zoubida, Zaidi Maysaa El Sayed, Zaki Carlos Zambrana, Torrelio Tomas, Zapata Elias Asfaw, Zegeye Yi, Zhao Maigeng, Zhou Sanjay, Zodpey David, Zonies Christopher J. L., Murray

Journal:

Content:

Date:

2016-01-01

Authors:

Ameh OI Swanepoel CR Aderibigbe A Kengne AP Okpechi IG

Journal:

Nephrology (Carlton, Vic.)

Content:

Date:

2016-12-01

Authors:

Dzudie A Kengne AP Mbahe S Menanga A Kenfack M Kingue S

Journal:

European journal of heart failure

Content:

Date:

2008-03-01

Authors:

Tandi E. Matsha Carmen Pheiffer Tinashe Mutize Rajiv T. Erasmus Andre P. Kengne

Journal:

Journal of Diabetes Research

Content:

Date:

2016-01-01

Authors:

Fezeu L Kengne AP Balkau B Awah PK Mbanya JC

Journal:

Journal of epidemiology and community health

Content:

Date:

2009-08-01

Authors:

Krishnamurthi RV Moran AE Feigin VL Barker-Collo S Norrving B Mensah GA Taylor S Naghavi M Forouzanfar MH Nguyen G Johnson CO Vos T GBD 2013 Stroke Panel Experts Group

Journal:

Neuroepidemiology

Content:

Date:

2015-10-01

Authors:

Kengne AP Mayosi BM

Journal:

The Lancet. Global health

Content:

Date:

2018-02-01

Authors:

Davidson FE Matsha TE Erasmus RT Kengne AP Goedecke JH

Journal:

Cardiovascular journal of Africa

Content:

Date:

2019-09-01

Authors:

Mohsen Mazidi Maciej Banach Andre Pascal Kengne Lipid and Blood Pressure Meta-analysis Collaboration Group

Journal:

Content:

Date:

2018-01-01

Authors:

Balde N Camara A Sobngwi-Tambekou J Balti EV Tchatchoua A Fezeu L Limen S Ngamani S Ngapout S Kengne AP Sobngwi E

Journal:

The Pan African medical journal

Content:

Date:

2017-08-01

Authors:

George C Mogueo A Okpechi I Echouffo-Tcheugui JB Kengne AP

Journal:

BMJ global health

Content:

Date:

2017-05-01

Authors:

NCD Risk Factor Collaboration (NCD-RisC)

Journal:

Lancet (London, England)

Content:

Date:

2016-11-01

Authors:

GBD Chronic Respiratory Disease Collaborators

Journal:

The Lancet. Respiratory medicine

Content:

Date:

2020-06-01

Authors:

Maryam Bibi Rumaney Valentina Josiane Ngo Bitoungui Anna Alvera Vorster Raj Ramesar Andre Pascal Kengne Jeanne Ngogang Ambroise Wonkam

Journal:

Content:

BACKGROUND: Co-inheritance of α-thalassemia was reported to be associated with a delayed age of disease onset among Cameroonian Sickle Cell Anemia (SCA) patients. The present study aimed to explore the correlation between α-thalassemia, hematological indices, and clinical events in these patients. METHODS AND FINDINGS: We studied 161 Cameroonian SCA patients and 103 controls (59.1% HbAA) with median ages of 17.5 and 23 years. RFLP-PCR was used to confirm SCA genotype and to describe haplotypes in the HBB-like genes cluster. Multiplex Gap-PCR was performed to investigate the 3.7 kb α-globin gene deletions. SNaPshot PCR, capillary electrophoresis and cycle sequencing were used for the genotyping of 10 SNPs in BCL11A, HMIP1/2, OR51B5/6 and HBG loci, known to influence HbF levels. Generalised linear regression models adjusted for age, sex and SNPs genotypes was used to investigate effects of α-thalassemia on clinical and hematological indices. The median rate of vaso-occlusive painful crisis and hospitalisations was two and one per year, respectively. Stroke was reported in eight cases (7.4%). Benin haplotype was the most prevalent (66.3%; n = 208 chromosomes). Among patients, 37.3% (n = 60) had at least one 3.7 kb deletion, compared to 10.9% (n = 6) among HbAA controls (p<0.001). Among patients, the median RBC count increased with the number of 3.7 kb deletions [2.6, 3.0 and 3.4 million/dl, with no, one and two deletions (p = 0.01)]. The median MCV decreased with the number of 3.7 kb deletion [86, 80, and 68fl, with no, one and two deletions (p<0.0001)], as well as median WBC counts [13.2, 10.5 and 9.8×109/L (p<0.0001. The co-inheritance of α-thalassemia was associated with lower consultations rate (p = 0.038). CONCLUSION: The co-inheritance of α-thalassemia and SCA is associated with improved hematological indices, and lower consultations rate in this group of patients. This could possibly improve their survival and explain the higher proportion of α-thalassemia among patients than controls.

Date:

Authors:

Werfalli M Musekiwa A Engel ME Ross I Kengne AP Levitt NS

Journal:

BMJ open

Content:

Date:

2014-06-01

Authors:

Ekrikpo UE Kengne AP Akpan EE Effa EE Bello AK Ekott JU George C Salako BL Okpechi IG

Journal:

Medicine

Content:

Date:

2018-04-01

Authors:

Ahmadou M Jingi Jean Jacques N Noubiap Arnold Ewane Onana Jobert Richie N Nansseu Binhuan Wang Samuel Kingue André Pascal Kengne

Journal:

Content:

To assess the availability and affordability of medicines and routine tests for cardiovascular disease (CVD) and diabetes in the West region of Cameroon, a low-income setting.A survey was conducted on the availability and cost of twelve routine tests and twenty medicines for CVD and diabetes in eight health districts (four urban and four rural) covering over 60% of the population of the region (1.8 million). We analyzed the percentage of tests and medicines available, the median price against the international reference price (median price ratio) for the medicines, and affordability in terms of the number of days' wages it would cost the lowest-paid unskilled government worker for initial investigation tests and procurement for one month of treatment.The availability of tests varied between 10% for the ECG to 100% for the fasting blood sugar. The average cost for the initial investigation using the minimum tests cost 29.76 days' wages. The availability of medicines varied from 36.4% to 59.1% in urban and from 9.1% to 50% in rural settings. Only metformin and benzathine-benzylpenicilline had a median price ratio of ≤ 1.5, with statins being largely unaffordable (at least 30.51 days' wages). One month of combination treatment for coronary heart disease costs at least 40.87 days' wages.The investigation and management of patients with medium-to-high cardiovascular risk remains largely unavailable and unaffordable in this setting. An effective non-communicable disease program should lay emphasis on primary prevention, and improve affordable access to essential medicines in public outlets.

Date:

Authors:

Lassale C Fezeu L Andreeva VA Hercberg S Kengne AP Czernichow S Kesse-Guyot E

Journal:

International journal of obesity (2005)

Content:

Date:

2012-01-01

Authors:

Echouffo-Tcheugui JB Batty GD Kivimäki M Kengne AP

Journal:

PloS one

Content:

Date:

2013-07-01

Authors:

Patel A Cass A Peiris D Usherwood T Brown A Jan S Neal B Hillis GS Rafter N Tonkin A Webster R Billot L Bompoint S Burch C Burke H Kanyini Guidelines Adherence with the Polypill (Kanyini GAP) Collaboration

Journal:

European journal of preventive cardiology

Content:

Date:

2014-03-01

Authors:

Mazidi M Rezaie P Kengne AP Mobarhan MG Ferns GA

Journal:

Diabetes & metabolic syndrome

Content:

Date:

2016-02-01

Authors:

Joseph PG Healey JS Raina P Connolly SJ Ibrahim Q Gupta R Avezum A Dans AL Lopez-Jaramillo P Yeates K Teo K Douma R Bahonar A PURE Investigators

Journal:

Cardiovascular research

Content:

Date:

2021-05-01

Authors:

GBD 2016 Alcohol Collaborators

Journal:

Lancet (London, England)

Content:

Date:

2018-08-01

Authors:

Choukem SP Kengne AP Dehayem YM Simo NL Mbanya JC

Journal:

Diabetes research and clinical practice

Content:

Date:

2006-12-01

Authors:

NCD Risk Factor Collaboration (NCD-RisC) – Africa Working Group

Journal:

International journal of epidemiology

Content:

Date:

2017-10-01

Authors:

Choukem SP Fabreguettes C Akwo E Porcher R Nguewa JL Bouche C Kaze FF Kengne AP Vexiau P Mbanya JC Sobngwi E Gautier JF

Journal:

Diabetes & metabolism

Content:

Date:

2013-09-01

Authors:

GBD 2015 HIV Collaborators

Journal:

The lancet. HIV

Content:

Date:

2016-07-01

Authors:

Mazidi M Shivappa N Wirth MD Hebert JR Mikhailidis DP Kengne AP Banach M

Journal:

Atherosclerosis

Content:

Date:

2018-02-01

Authors:

Nkoke C Lekoubou A Dzudie A Jingi AM Kingue S Menanga A Kengne AP

Journal:

BMC pediatrics

Content:

Date:

2016-03-01

Authors:

GBD 2015 DALYs and HALE Collaborators

Journal:

Lancet (London, England)

Content:

Date:

2016-10-01

Authors:

Lekoubou A Njouoguep R Kuate C Kengne AP

Journal:

BMC neurology

Content:

Date:

2010-06-01

Authors:

Echouffo-Tcheugui JB Dieffenbach SD Kengne AP

Journal:

Diabetes research and clinical practice

Content:

Date:

2013-05-01

Authors:

Steyn NP Mchiza ZJ Kengne AP

Journal:

Expert review of endocrinology & metabolism

Content:

Date:

2014-10-01

Authors:

Dzudie A Choukem SP Adam AK Kengne AP Gouking P Dehayem M Kamdem F Doualla MS Joko HA Lobe ME Mbouende YM Luma H Mbanya JC Kingue S

Journal:

Cardiovascular journal of Africa

Content:

Date:

2012-09-01

Authors:

Saarah Fatoma Gadija Davids Tandi Edith Matsha Nasheeta Peer Rajiv Timothy Erasmus Andre Pascal Kengne

Journal:

Journal of Diabetes Research

Content:

Date:

2020-05-22

Authors:

Chikte U Pontes CC Karangwa I Kimmie-Dhansay F Erasmus R Kengne AP Matsha TE

Journal:

International dental journal

Content:

Date:

2019-12-01

Authors:

Chalmers J Joshi R Kengne AP MacMahon S

Journal:

Journal of hypertension. Supplement : official journal of the International Society of Hypertension

Content:

Date:

2008-06-01

Authors:

Asia Pacific Cohort Studies Collaboration Kengne AP Patel A Barzi F Jamrozik K Lam TH Ueshima H Gu DF Suh I Woodward M

Journal:

Journal of hypertension

Content:

Date:

2007-06-01

Authors:

Mazidi M Kengne AP Banach M

Journal:

Polish archives of internal medicine

Content:

Date:

2017-02-01

Authors:

Okpechi IG Ameh OI Bello AK Ronco P Swanepoel CR Kengne AP

Journal:

PloS one

Content:

Date:

2016-03-01

Authors:

Geard A Pule GD Chetcha Chemegni B Ngo Bitoungui VJ Kengne AP Chimusa ER Wonkam A

Journal:

British journal of haematology

Content:

Date:

2017-05-01

Authors:

GBD 2016 SDG Collaborators

Journal:

Lancet (London, England)

Content:

Date:

2017-09-01

Authors:

Dehayem YM Kengne AP Choukem SP Simo NL Awah KP Mbanya JC

Journal:

Annals of tropical medicine and parasitology

Content:

Date:

2008-01-01

Authors:

Asanda Mtintsilana Lisa K. Micklesfield Elin Chorell Tommy Olsson Nitin Shivappa James R Hebert Andre P. Kengne Julia H. Goedecke

Journal:

Nutrients

Content:

Date:

2019-05-31

Authors:

Kengne AP Fezeu L Sobngwi E Awah PK Aspray TJ Unwin NC Mbanya JC

Journal:

Primary care diabetes

Content:

Date:

2009-08-01

Authors:

Kengne AP Kaze FF Dzudie A Awah PK Ngu KB

Journal:

Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002)

Content:

Date:

2007-03-01

Authors:

Yuyun MF Bonny A Ng GA Sliwa K Kengne AP Chin A Mocumbi AO Ngantcha M Ajijola OA Bukhman G

Journal:

Global heart

Content:

Date:

2020-05-01

Authors:

GBD 2017 Risk Factor Collaborators

Journal:

Lancet (London, England)

Content:

Date:

2018-11-01

Authors:

Tandi E. Matsha Carmen Pheiffer Stephen E. Humphries Junaid Gamieldien Rajiv T. Erasmus Andre P. Kengne

Journal:

International Journal of Endocrinology

Content:

Date:

2016-01-01

Authors:

Eugene Sobngwi Andre Pascal Kengne Leopold Fezeu Paschal Awah Alain Lekoubou

Journal:

Content:

Chronic diseases are becoming increasingly important in sub-Saharan Africa (SSA). The current density and distribution of health workforce suggest that SSA cannot respond to the growing demand for chronic disease care, together with the frequent infectious diseases. Innovative approaches are therefore needed to rapidly expand the health workforce. In this article, we discuss the evidences in support of nurse-led strategies for chronic disease management in SSA, with a focus on hypertension and diabetes mellitus.

Date:

2010-01-01

Authors:

Choukem SP Sih C Nebongo D Tientcheu P Kengne AP

Journal:

The Pan African medical journal

Content:

Date:

2019-03-01

Authors:

Kengne AP Awah PK Fezeu LL Sobngwi E Mbanya JC

Journal:

Journal of clinical hypertension (Greenwich, Conn.)

Content:

Date:

2009-10-01

Authors:

Kim Anh Nguyen Nasheeta Peer Anniza de Villiers Barbara Mukasa Tandi E. Matsha Edward J. Mills Andre Pascal Kengne

Journal:

International Journal of Endocrinology

Content:

Date:

2017-01-01

Authors:

Ekrikpo UE Okuku CN Ajayi SO Ayodele OE Bello AK Wonkam A Dandara C Kengne AP Okpechi I

Journal:

Kidney international reports

Content:

Date:

2019-07-01

Authors:

Faheema Kimmie-Dhansay Carla Cruvinel Pontes Usuf M. E. Chikte Albert Chinhenzva Rajiv T. Erasmus Andre Pascal Kengne Tandi E. Matsha

Journal:

International Journal of Environmental Research and Public Health

Content:

Date:

2021-05-08

Authors:

Vergotine Z Yako YY Kengne AP Erasmus RT Matsha TE

Journal:

BMC genetics

Content:

Date:

2014-01-01

Authors:

Lontchi-Yimagou E Sobngwi E Matsha TE Kengne AP

Journal:

Current diabetes reports

Content:

Date:

2013-06-01

Authors:

Echouffo-Tcheugui JB Woodward M Kengne AP

Journal:

Journal of thrombosis and haemostasis : JTH

Content:

Date:

2013-05-01

Authors:

Kengne AP Beulens JW Peelen LM Moons KG van der Schouw YT Schulze MB Spijkerman AM Griffin SJ Grobbee DE Palla L Tormo MJ Arriola L Wareham NJ

Journal:

The lancet. Diabetes & endocrinology

Content:

Date:

2013-10-01

Authors:

Echouffo-Tcheugui JB Kengne AP

Journal:

Circulation

Content:

Date:

2013-11-01

Authors:

Andre Pascal Kengne Alfred Kongnyu Njamnshi Jean Claude Mbanya

Journal:

Content:

Background The growing burden of type 2 diabetes in Sub-Saharan Africa (SSA) and related cardiovascular complications call for vigorous actions into prevention. Comprehensive cardiovascular risk evaluation is important for the success of such actions. Methods We have reviewed 3 currently existing sets of recommendations for cardiovascular prevention in diabetes in SSA. Distribution of major risk factors and patterns of reported cardiovascular outcomes are used to suggest orientations for cardiovascular prevention in diabetes in this region. Papers and reports published over the period 1990 to 2007 were used. Results Existing guidelines share some similarities, but also have areas of inconsistencies. They are generally adaptations of existing guidelines, focused more on individual risk factors, and are not usually backed-up by local evidence. They all have a projection on blood pressure lowering. This focus is supported by the high prevalence of hypertension among people with diabetes in SSA. Blood pressure and tobacco smoking are the modifiable risk factors accessible to evaluation and interventions on a wide scale in SSA. Appropriate blood pressure control will have a major impact on stroke (the commonest cardiovascular disease) through a reduction of the cerebrovascular risk, and to a lesser extent on coronary heart disease and total deaths in diabetes in this region. Conclusions In the absence of global risk evaluation tools, the use of blood pressure lowering as a primary focus of cardiovascular prevention strategies is relevant for SSA. However, there is a need to set-up diabetes and stroke registers to monitor outcomes and generate tools for accurate risk prediction and management in diabetes in this region.

Date:

2008-01-01

Authors:

Barker-Collo S Bennett DA Krishnamurthi RV Parmar P Feigin VL Naghavi M Forouzanfar MH Johnson CO Nguyen G Mensah GA Vos T Murray CJ GBD 2013 Stroke Panel Experts Group

Journal:

Neuroepidemiology

Content:

Date:

2015-10-01

Authors:

GBD 2017 Stomach Cancer Collaborators

Journal:

The lancet. Gastroenterology & hepatology

Content:

Date:

2019-10-01

Authors:

Marie Laure Gharingam Boniface Moifo Eric Walter Pefura Yone André Pascal Kengne Jean Roger Moulion Tapouh Annick Laure Edzimbi Georges Nguefack-Tsague Samuel Nko’o Amvene

Journal:

Open Journal of Medical Imaging

Content:

Date:

2014-01-01

Authors:

Joshi R Kengne AP Neal B

Journal:

Bulletin of the World Health Organization

Content:

Date:

2009-09-01

Authors:

Adom T Puoane T De Villiers A Kengne AP

Journal:

BMJ open

Content:

Date:

2017-03-01

Authors:

Chivese T Werfalli MM Magodoro I Chinhoyi RL Kengne AP Norris SA Levitt NS

Journal:

BMJ open

Content:

Date:

2019-05-01

Authors:

Mazidi M Rezaie P Karimi E Kengne AP

Journal:

International journal of cardiology

Content:

Date:

2016-10-01

Authors:

Mazidi M Rezaie P Jangjoo A Tavassoli A Rajabi MT Kengne AP Nematy M

Journal:

World journal of diabetes

Content:

Date:

2017-07-01

Authors:

GBD 2013 Risk Factors Collaborators Forouzanfar MH Alexander L Anderson HR Bachman VF Biryukov S Brauer M Burnett R Casey D Coates MM Murray CJ

Journal:

Lancet (London, England)

Content:

Date:

2015-09-01

Authors:

Justin B Echouffo-Tcheugui Andre P Kengne

Journal:

European Heart Journal

Content:

Date:

2019-08-01

Authors:

Lekoubou A Awoumou JJ Kengne AP

Journal:

International journal of stroke : official journal of the International Stroke Society

Content:

Date:

2017-09-01

Authors:

Kaze FF Kengne AP Mambap AT Halle MP Mbanya D Ashuntantang G

Journal:

African health sciences

Content:

Date:

2015-03-01

Authors:

NCD Countdown 2030 collaborators

Journal:

Lancet (London, England)

Content:

Date:

2020-09-01

Authors:

Mhandire DZ Mhandire K Magadze M Wonkam A Kengne AP Dandara C

Journal:

BMC medical genetics

Content:

Date:

2020-05-01

Authors:

Dipuo D. Motshwari Cindy George Don M. Matshazi Cecil J. Weale Saarah F. G. Davids Rajiv T. Erasmus Andre P. Kengne Tandi E. Matsha

Journal:

Applied Sciences

Content:

Date:

2021-08-20

Authors:

NCD Risk Factor Collaboration (NCD-RisC)

Journal:

The lancet. Diabetes & endocrinology

Content:

Date:

2015-06-01

Authors:

Muyunda Buwa Anniza deVilliers Andre Pascal Kengne

Journal:

Content:

Background Smoking is one of the major preventable causes of disease and premature death globally. Emerging findings have highlighted the intersection of cigarette smoking and HIV/AIDS as a significant public health concern. For adults with HIV, smoking increases both HIV-related and non-related outcomes. There is scarcity of information on the incidence and effects of cigarette smoking as well as its management in the HIV-infected population in South Africa. This study therefore aimed to determine the occurrence of smoking in HIV positive patients attending public healthcare facilities in the Western Cape Province of South Africa. Methods An overall of 751 patients living with HIV randomly selected and screened from 17 different HIV/AIDS public facilities in the Western Cape at both primary and secondary level were included for this study between 2014 and 2015. This article focuses on the self-reported tobacco-using behavior of adults aged >18 years. The survey instrument included questions on the respondents´ history of smoking tobacco, current use of other tobacco products, frequency and duration of use, and attempts to stop smoking tobacco or using other tobacco products. Results Of the 751 HIV positive patients receiving medical care at public healthcare facilities, an overall of 20.7% (95% CI, 17.3% to 24.1%) were current smokers, 14.5% (CI, 11.6% to 17.4%) were former smokers, while 65.3% (CI, 54.6% to 68.9%) had never smoked. Out of these the current smokers, 18.9% (95% CI, 12.3% to 25.5%) were men while 20.8% (95% CI, 16.9% to 24.7%) were women. Among the patients living with HIV, factors independently associated with greater smoking prevalence were gender, age, unemployment, household smoking, and excessive alcohol use. Conclusions We found a high prevalence of hypertension among patients receiving routine care for HIV infection across public HIV clinics in this setting.

Date:

2018-01-01

Authors:

Wonkam A Mnika K Ngo Bitoungui VJ Chetcha Chemegni B Chimusa ER Dandara C Kengne AP

Journal:

British journal of haematology

Content:

Date:

2017-12-01

Authors:

Mazidi M Vadadian P Rezaie P Azarpazhooh MR Esmaeili H Ghayour-Mobarhan M Kengne AP Ferns GA

Journal:

Diabetes & metabolic syndrome

Content:

Date:

2016-08-01

Authors:

Nguyen KA Peer N de Villiers A Mukasa B Matsha TE Mills EJ Kengne AP

Journal:

PloS one

Content:

Date:

2019-01-01

Authors:

Echouffo-Tcheugui JB Yaya S Joshi R Narayan KMV Kengne AP

Journal:

BMJ Global Health

Content:

Date:

2018-10-01

Authors:

Mazidi M Rezaie P Covic A Malyszko J Rysz J Kengne AP Banach M

Journal:

Oncotarget

Content:

Date:

2017-09-01

Authors:

Atun R Davies JI Gale EAM Bärnighausen T Beran D Kengne AP Levitt NS Mangugu FW Nyirenda MJ Ogle GD Ramaiya K Sewankambo NK Sobngwi E Werfalli M

Journal:

The lancet. Diabetes & endocrinology

Content:

Date:

2017-07-01

Authors:

GBD 2017 Causes of Death Collaborators

Journal:

Lancet (London, England)

Content:

Date:

2018-11-01

Authors:

Werfalli M Raubenheimer P Engel M Peer N Kalula S Kengne AP Levitt NS

Journal:

BMJ open

Content:

Date:

2015-07-01

Authors:

Kaze FF Ashuntantang G Halle MP Kengne AP

Journal:

Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy

Content:

Date:

2014-09-01

Authors:

Echouffo-Tcheugui JB Kengne AP

Journal:

The Pan African medical journal

Content:

Date:

2012-04-01

Authors:

Poka-Mayap V Pefura-Yone EW Kengne AP Kuaban C

Journal:

BMJ open

Content:

Date:

2013-07-01

Authors:

Ekrikpo UE Kengne AP Bello AK Effa EE Noubiap JJ Salako BL Rayner BL Remuzzi G Okpechi IG

Journal:

PloS one

Content:

Date:

2018-04-01

Authors:

Nkoke C Lekoubou A Balti E Kengne AP

Journal:

Journal of the neurological sciences

Content:

Date:

2015-08-01

Authors:

Murray CJ Ortblad KF Guinovart C Lim SS Wolock TM Roberts DA Dansereau EA Graetz N Barber RM Brown JC Wang H Duber HC Naghavi M Vos T

Journal:

Lancet (London, England)

Content:

Date:

2014-07-01

Authors:

Griesel R Stewart A van der Plas H Sikhondze W Rangaka MX Nicol MP Kengne AP Mendelson M Maartens G

Journal:

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Content:

Date:

2018-04-01

Authors:

Mohsen Mazidi Niki Katsiki Andre Pascal Kengne Dimitri P. Mikhailidis Maciej Banach

Journal:

Content:

Abstract Background Growing evidence suggests an inverse association between whole grain (WG) consumption and insulin resistance (IR) or inflammation. However, it is still unclear whether adiposity plays a role in this relationship. We investigated whether the associations between WG intake with IR, glucose homeostasis and inflammation are mediated by adiposity in US adults. Methods The 2005–2010 National Health and Nutrition Examination Surveys participants were included. WG intake was assessed and markers of IR and glucose homeostasis, inflammation, general and central adiposity. Analysis of co-variance and mediation analysis were applied, while accounting for survey design. Results Overall 16,621 participants were included in this analysis (mean age = 47.1 years, 48.3% men). After adjustment for age, gender, and race, mean C-reactive protein (CRP), apolipoprotein B (apo-B), fasting blood glucose (FBG), insulin, homeostatic model assessment of IR (HOMA-IR) and β cell function (HOMA-β), hemoglobin A1c (HbA1c), and 2 h glucose after an oral glucose tolerance test decreased with increasing quarters of WG (all p < 0.001). Body mass index (BMI) had significant mediation effects on the associations between WG intake and CRP, apo-B, fasting glucose, insulin, HOMA-IR, HOMA-B, HbA1c, triglyceride to high density lipoprotein-cholesterol (TG:HDL-C) ratio and triglyceride-glucose (TyG) index (all p < 0.05) after adjustment for age, gender, race/ethnicity, educational status, smoking and level of physical activity. Both waist circumference (WC) and anthropometrically predicted visceral adipose tissue (apVAT) mediated the association between WG intakes with CRP, FBG, HbA1c, TG:HDL-C ratio and TyG index, i.e. WC and apVAT had indirect effect (all p < 0.05). Conclusion Our findings provide insights into the favourable impact of WG consumption on IR and inflammation, which may be affected by both central and visceral adiposity, i.e. the link between WG with IR and inflammation is more mediated in overweight/obese compared with lean individuals.

Date:

2018-01-01

Authors:

GBD 2015 Obesity Collaborators Afshin A Forouzanfar MH Reitsma MB Sur P Estep K Lee A Marczak L Mokdad AH Moradi-Lakeh M Naghavi M Murray CJL

Journal:

The New England journal of medicine

Content:

Date:

2017-06-01

Authors:

GBD 2016 Healthcare Access and Quality Collaborators

Journal:

Lancet (London, England)

Content:

Date:

2018-06-01

Authors:

Kengne AP Echouffo-Tcheugui JB Sobngwi E Mbanya JC

Journal:

Heart (British Cardiac Society)

Content:

Date:

2013-05-01

Authors:

Mbanya VN Mbanya JC Kufe C Kengne AP

Journal:

Journal of clinical hypertension (Greenwich, Conn.)

Content:

Date:

2016-02-01

Authors:

Lopes T Zemlin AE Faber M Durao S Erasmus RT Kengne AP

Journal:

Content:

Date:

2021-08-01

Authors:

Businge CB Usenbo A Longo-Mbenza B Kengne AP

Journal:

BMJ open

Content:

Date:

2021-02-01

Authors:

Theodosia Adom Anniza De Villiers Thandi Puoane André Pascal Kengne

Journal:

Nutrients

Content:

Date:

2019-12-30

Authors:

Journal:

International nursing review

Content:

Qualitative and quantitative approaches were used in a rural hospital of Cameroon to assess how much nursing personnel know about and practise in regard to human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS), and to determine health service factors that influence knowledge, attitudes and practices (KAP). Participants included 107 nursing and laboratory staff and 62 patients with AIDS. Self-administered questionnaires were used for nurses, and close-ended questionnaires were administered to patients with AIDS (as a verification tool for staff responses). Focus group discussions (FGD) held with nurse supervisors evaluated health service factors that influence KAP. Overall, 70.1% of the nurses who responded scored highly in the knowledge section compared to 50.5% in the attitude and practice section. There were several outstanding misconceptions and malpractices about HIV/AIDS. Knowledge, but not attitude, was significantly influenced by the grade of the staff (P< 0.001 and P = 0.17, respectively). Approximately 15% of 62 patients with AIDS indicated that they were attended to with signs of disgust and/or hatred. The major health service factors thought to influence KAP, confirmed by many in all the FGD, included: the lack of adequate information; the lack of commitment to alter attitudes and practices; the lack of in-service promotions; and the ongoing fear of becoming infected with the virus through caring for patients with AIDS. Low income also seemed to have an influence on KAP. Therefore, it is imperative that ongoing education programmes are provided for nurses to enable them to meet the needs of the increasing HIV prevalence in our community. Information, education and communication, and compliance with international working norms, remain essential tools in the control of HIV/AIDS spread in our hospital settings.

Date:

2001-12-01

Authors:

Lekoubou A Echouffo-Tcheugui JB Kengne AP

Journal:

BMC public health

Content:

Date:

2014-06-01

Authors:

Dzudie A Barche B Mouliom S Nouko A Fogue R Ndjebet J Makoh SA Abah J Djomou A Nzali A Nkoke C Kamdem F Kingue S Sliwa K Kengne AP

Journal:

Cardiovascular diagnosis and therapy

Content:

Date:

2021-02-01

Authors:

Nguyen KA Peer N Mills EJ Kengne AP

Journal:

AIDS reviews

Content:

Date:

2015-04-01

Authors:

Matsha TE Prince Y Davids S Chikte U Erasmus RT Kengne AP Davison GM

Journal:

Journal of dental research

Content:

Date:

2020-04-01

Authors:

Boateng D Agyemang C Kengne AP Grobbee DE Klipstein-Grobusch K RODAM consortium

Journal:

International journal of cardiology

Content:

Date:

2018-08-01

Authors:

Mazidi M Rezaie P Kengne AP Stathopoulou MG Azimi-Nezhad M Siest S

Journal:

Diabetes & metabolic syndrome

Content:

Date:

2016-12-01

Authors:

van Dieren S Czernichow S Chalmers J Kengne AP de Galan BE Poulter N Woodward M Beulens JW Grobbee DE van der Schouw YT Zoungas S

Journal:

Diabetes, obesity & metabolism

Content:

Date:

2012-02-01

Authors:

Takah N Dzudie A Ndjebet J Wawo G Kamdem F Monkam Y Luma H Ngu KB Kengne AP

Journal:

The Pan African medical journal

Content:

Date:

2014-11-01

Authors:

Pefura-Yone EW Balkissou AD Kengne AP

Journal:

The open respiratory medicine journal

Content:

Date:

2016-11-01

Authors:

Mbanya VN Kengne AP Mbanya JC Akhtar H

Journal:

Diabetes research and clinical practice

Content:

Date:

2015-01-01

Authors:

GBD 2015 Risk Factors Collaborators

Journal:

Lancet (London, England)

Content:

Date:

2016-10-01

Authors:

George C Stoker S Okpechi I Woodward M Kengne A CKD-Africa Collaboration

Journal:

BMJ global health

Content:

Date:

2021-08-01

Authors:

NCD Risk Factor Collaboration (NCD-RisC)

Journal:

Lancet (London, England)

Content:

Date:

2017-10-01

Authors:

Victoria Pinkney-Atkinson Kim Nguyen June- Rose Zandile Mchiza Mukesh Muke Helene Mwamba Lushiku Nkombua Andre Pascal Kengne

Journal:

Content:

Date:

2015-01-01

Authors:

Pefura-Yone EW Kengne AP Kuaban C

Journal:

BMC infectious diseases

Content:

Date:

2014-03-01

Authors:

Journal:

International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity

Content:

OBJECTIVES: To evaluate and compare physical activity patterns of urban and rural dwellers in Cameroon, and study their relationship with obesity, diabetes and hypertension. METHODS: We studied 2465 subjects aged >or=15 y, recruited on the basis of a random sampling of households, of whom 1183 were urban dwellers from Yaoundé, the capital city of Cameroon and 1282 rural subjects from Bafut, a village of western Cameroon. They all had an interviewer-administered questionnaire for the assessment of their physical activity and anthropometric measurements, blood pressure and fasting blood glucose determination. The procedure was satisfactorily completed in 2325 (94.3%) subjects. Prevalences were age-adjusted and subjects compared according to their region, sex and age group. RESULTS: Obesity was diagnosed in 17.1 and 3.0% urban and rural women, respectively (P<0.001), and in 5.4 vs 1.2% urban and rural men, respectively (P<0.001). The prevalence of hypertension was significantly higher in urban vs rural dwellers (11.4 vs 6.6% and 17.6 vs 9.1% in women and men, respectively; P<0.001). Diabetes was more prevalent in urban compared to rural women (P<0.05), but not men. Urban subjects were characterized by lower physical activity (P<0.001), light occupation, high prevalence of multiple occupations, and reduced walking and cycling time compared to rural subjects. Univariate analysis showed significant associations between both physical inactivity and obesity and high blood pressure. The relationship of physical inactivity with hypertension and obesity were independent in both urban and rural men, but not in women. Body mass index, blood pressure and glycaemia were higher in the first compared with the fourth quartiles of energy expenditure. CONCLUSION: Obesity, diabetes and hypertension prevalence is higher in urban compared to rural dwellers in the populations studied. Physical activity is significantly lower and differs in pattern in urban subjects compared to rural. Physical inactivity is associated with these diseases, although not always significant in women.

Date:

2002-07-01

Authors:

Yuyun MF Sliwa K Kengne AP Mocumbi AO Bukhman G

Journal:

Global heart

Content:

Date:

2020-02-01

Authors:

Malambo P Kengne AP De Villiers A Lambert EV Puoane T

Journal:

PloS one

Content:

Date:

2016-11-01

Authors:

Igwesi-Chidobe CN Kengne AP Sorinola IO Godfrey EL

Journal:

International health

Content:

Date:

2018-05-01

Authors:

Usuf Chikte Carla Cruvinel Pontes Innocent Karangwa Faheema Kimmie-Dhansay Rajiv T. Erasmus Andre P. Kengne Tandi E. Matsha

Journal:

International Journal of Environmental Research and Public Health

Content:

Date:

2019-09-29

Authors:

Dzudie A Ojji D Damasceno A Sani MU Kramoh E Kacou JB Anisiuba B Ogola E Awad M Nel G Otieno H Toure AI Kane A Kengne AP Ngwasiri C PASCAR task force on hypertension

Journal:

Cardiovascular journal of Africa

Content:

Date:

2018-09-01

Authors:

GBD 2016 Lifetime Risk of Stroke Collaborators Feigin VL Nguyen G Cercy K Johnson CO Alam T Parmar PG Abajobir AA Abate KH Abd-Allah F Roth GA

Journal:

The New England journal of medicine

Content:

Date:

2018-12-01

Authors:

Mohsen Mazidi Andre P. Kengne Mario Siervo Richard Kirwan

Journal:

Nutrients

Content:

Date:

2022-03-15

Authors:

Businge CB Longo-Mbenza B Kengne AP

Journal:

Systematic reviews

Content:

Date:

2019-08-01

Authors:

Dzudie A Kengne AP Muna WF Ba H Menanga A Kouam Kouam C Abah J Monkam Y Biholong C Mintom P Kamdem F Djomou A Ndjebet J Wambo C Luma H CCS investigator group

Journal:

BMJ open

Content:

Date:

2012-08-01

Authors:

GBD 2017 SDG Collaborators

Journal:

Lancet (London, England)

Content:

Date:

2018-11-01

Authors:

Mazidi M Kengne AP Vatanparast H

Journal:

Public health nutrition

Content:

Date:

2018-05-01

Authors:

Shlipak MG Tummalapalli SL Boulware LE Grams ME Ix JH Jha V Kengne AP Madero M Mihaylova B Tangri N Cheung M Jadoul M Winkelmayer WC Conference Participants

Journal:

Kidney international

Content:

Date:

2020-10-01

Authors:

Kengne AP Batty GD Hamer M Stamatakis E Czernichow S

Journal:

Diabetes care

Content:

Date:

2011-12-01

Authors:

Woodward M Hirakawa Y Kengne AP Matthews DR Zoungas S Patel A Poulter N Grobbee R Cooper M Jardine M Chalmers J ADVANCE Collaborative Group

Journal:

Diabetes, obesity & metabolism

Content:

Date:

2016-01-01

Authors:

Jaspers Faijer-Westerink H Kengne AP Meeks KAC Agyemang C

Journal:

Nutrition, metabolism, and cardiovascular diseases : NMCD

Content:

Date:

2020-03-01

Authors:

Brown BJ Madu A Sangeda RZ Nkya S Peprah E Paintsil V Mmbando BP Gyamfi J Okocha CE Asala SA Nembaware V Jonas M Kengne AP Chimusa ER SickleInAfrica Consortium

Journal:

Hemoglobin

Content:

Date:

2021-05-01

Authors:

Kengne AP June-Rose McHiza Z Amoah AG Mbanya JC

Journal:

Progress in cardiovascular diseases

Content:

Date:

2013-10-01

Authors:

Prabhakaran D Anand S Watkins D Gaziano T Wu Y Mbanya JC Nugent R Disease Control Priorities-3 Cardiovascular Respiratory and Related Disorders Author Group

Journal:

Lancet (London, England)

Content:

Date:

2017-11-01

Authors:

Kengne AP Fezeu L Awah PK Sobngwi E Mbanya JC

Journal:

Epilepsia

Content:

Date:

2010-05-01

Authors:

Abrahams N Mhlongo S Dunkle K Chirwa E Lombard C Seedat S Kengne AP Myers B Peer N Garcia-Moreno C Jewkes R

Journal:

AIDS (London, England)

Content:

Date:

2021-03-01

Authors:

Gift Dineo Pule Valentina Josiane Ngo Bitoungui Bernard Chetcha Chemegni Andre Pascal Kengne Ambroise Wonkam

Journal:

Content:

Abstract Background Reactivation of adult hemoglobin (HbF) is currently a dominant therapeutic approach to sickle cell disease (SCD). In this study, we have investigated among SCD patients from Cameroon, the association of HbF level and variants in the HU-inducible small guanosine triphosphate-binding protein, secretion-associated and RAS-related (SAR1a) protein, previously shown to be associated with HbF after HU treatment in African American SCD patients. Results Only patients >5 years old were included; hemoglobin electrophoresis and a full blood count were conducted upon arrival at the hospital. RFLP-PCR was used to describe the HBB gene haplotypes and Gap PCR to investigate the 3.7 kb α-globin gene deletion. The iPLEX Gold Sequenom Mass Genotyping Array and cycle sequencing were used for the genotyping of four selected SNPs in SAR1a (rs2310991; rs4282891; rs76901216 and rs76901220). Genetic analysis was performed using an additive genetic model, under a generalized linear regression framework. 484 patients were studied. No associations were observed between any of the promoter variants and baseline HbF, clinical events or other hematological indices. Conclusion The results of this study could be explained by possible population-specificity of some tagging genomic variants associated with HbF production and illustrated the complexity of replicating HbF-promoting variants association results across African populations.

Date:

2017-01-01

Authors:

van Dieren S Kengne AP Chalmers J Beulens JW Davis TM Fulcher G Heller SR Patel A Colagiuri S Hamet P Mancia G Marre M Neal B Zoungas S

Journal:

Diabetes, obesity & metabolism

Content:

Date:

2013-12-01

Authors:

Fezeu L Balkau B Kengne AP Sobngwi E Mbanya JC

Journal:

Atherosclerosis

Content:

Date:

2006-10-01

Authors:

Mbanya JC Kengne AP Assah F

Journal:

Lancet (London, England)

Content:

Date:

2006-11-01

Authors:

LBD Double Burden of Malnutrition Collaborators

Journal:

Nature medicine

Content:

Date:

2020-04-01

Authors:

Noubiap JJ Balti EV Bigna JJ Echouffo-Tcheugui JB Kengne AP

Journal:

The Lancet. Global health

Content:

Date:

2018-12-01

Authors:

Kuate D Etoundi BC Azantsa BK Kengne AP Ngondi JL Oben JE

Journal:

Lipids in health and disease

Content:

Date:

2010-02-01

Authors:

Kotsedi Daniel Monyeki Hlengani James Siweya Han C. G. Kemper Andre P. Kengne Geofrey Musinguzi Mbelegem Rosina Nkwana Tebogo Mothiba Tumiso Malatji Shisana M.-A. Baloyi Rambelani Malema Lloyd Leach Moloko Matshipi Ramakgahlela Betty Sebati Mohlago Ablonia Seloka Eliot Sibuyi Suzan Mafoloa Monyeki

Journal:

International Journal of Environmental Research and Public Health

Content:

Date:

2020-10-15

Authors:

NCD Risk Factor Collaboration (NCD-RisC)

Journal:

International journal of epidemiology

Content:

Date:

2018-03-01

Authors:

Kim A. Nguyen Ethan Morgan Nasheeta Peer Andre P. Kengne

Journal:

PLOS ONE

Content:

Date:

2021-02-05

Authors:

Noubiap JJ Jingi AM Kengne AP

Journal:

Cardiovascular diagnosis and therapy

Content:

Date:

2014-10-01

Authors:

GBD 2015 Eastern Mediterranean Region Diabetes and Chronic Kidney Disease Collaborators

Journal:

International journal of public health

Content:

Date:

2017-08-01

Authors:

Andre Pascal Kengne Mark Hamer G. David Batty Emmanuel Stamatakis

Journal:

Content:

Background: Both anaemia and cardiovascular disease (CVD) are common in people with diabetes. While individually both characteristics are known to raise mortality risk, their combined influence has yet to be quantified. In this pooling project, we examined the combined impact of baseline haemoglobin levels and existing CVD on all-cause and CVD mortality in people with diabetes. We draw comparison of these effects with those apparent in diabetes-free individuals. Methods/Principal Findings: A combined analyses of 7 UK population-based cohorts resulted in 26,480 study members. There were 946 participants with physician-diagnosed diabetes, 2227 with anaemia [haemoglobin,13 g/dl (men) or,12 (women)], 2592 with existing CVD (stroke, ischaemic heart disease), and 21,396 with none of the conditions. Across diabetes and anaemia subgroups, and using diabetes-free, non-anaemic participants as the referent group, the adjusted hazard ratios (HR) were 1.46 (95 % CI: 1.30–1.63) for anaemia, 1.67 (1.45–1.92) for diabetes, and 2.10 (1.55–2.85) for diabetes and anaemia combined. Across combined diabetes, anaemia and CVD subgroups, and compared with non-anaemic, diabetes-free and CVD-free participants, HR (95 % CI) for all-cause mortality were 1.49 (1.32–1.69) anaemia, 1.60 (1.46–1.76) for existing CVD, and 1.66 (1.39–1.97) for diabetes alone. Equivalents were 2.13 (1.48–3.07) for anaemia and diabetes, 2.68 (2.14–3.36) for diabetes and existing CVD, and 3.25 (1.88–5.62) for the three combined. Patterns were similar for CVD mortality.

Date:

Authors:

Zemlin AE Matsha TE Kengne AP Erasmus RT

Journal:

Clinica chimica acta; international journal of clinical chemistry

Content:

Date:

2015-07-01

Authors:

Nasheeta Peer Jaya George Carl Lombard Naomi Levitt Andre-Pascal Kengne

Journal:

Clinica Chimica Acta

Content:

Date:

2021-08-01

Authors:

Nkoke C Lekoubou A Yonta EW Dzudie A Kengne AP

Journal:

Cardiovascular diagnosis and therapy

Content:

Date:

2014-12-01

Authors:

Dzudie A Njedock N Boombhi J Ba H Amougou SN Kamdem F Barche B Nzali A Njomou A Ngwasiri C Geh MM Azabji M Mefire AC Njamnshi AK Kengne AP

Journal:

Health science reports

Content:

Date:

2021-05-01

Authors:

GBD 2017 DALYs and HALE Collaborators

Journal:

Lancet (London, England)

Content:

Date:

2018-11-01

Authors:

Kengne AP Nakamura K Barzi F Lam TH Huxley R Gu D Patel A Kim HC Woodward M Asia Pacific Cohort Study Collaboration

Journal:

Journal of diabetes

Content:

Date:

2009-05-01

Authors:

Pefura-Yone EW Kengne AP Kuaban C

Journal:

BMJ open

Content:

Date:

2014-01-01

Authors:

Lekoubou A Kengne AP Fezeu L Mbanya JC

Journal:

Neurological research

Content:

Date:

2012-01-01

Authors:

Sobngwi E Kengne AP Echouffo-Tcheugui JB Choukem S Sobngwi-Tambekou J Balti EV Pearce MS Siaha V Mamdjokam AS Effoe V Lontchi-Yimagou E Mbanya JC

Journal:

BMC endocrine disorders

Content:

Date:

2014-08-01

Authors:

Owolabi MO Owolabi MO Yaria JO Daivadanam M Makanjuola AI Parker G Oldenburg B Vedanthan R Norris S Oguntoye AR Osundina MA Herasme O COUNCIL Initiative

Journal:

Diabetes care

Content:

Date:

2018-05-01

Authors:

Dzudie A Rayner B Ojji D Schutte AE Twagirumukiza M Damasceno A Ba SA Kane A Kramoh E Kacou JB Onwubere B Cornick R Sliwa K Anisiuba B PASCAR task force on hypertension

Journal:

Cardiovascular journal of Africa

Content:

Date:

2017-07-01

Authors:

Kengne AP Mayosi BM

Journal:

The Lancet. Global health

Content:

Date:

2014-04-01

Authors:

Dzudie A Hoover D Kim HY Ajeh R Adedimeji A Shi Q Pefura Yone W Nsame Nforniwe D Thompson Njie K Pascal Kengne A Ebasone PV Barche B Anastos K

Journal:

PloS one

Content:

Date:

2021-07-01

Authors:

Chalmers J Joshi R Kengne AP Ninomiya T Bi Y Bompoint S Billot L Patel A ADVANCE Collaborative Group

Journal:

Journal of hypertension. Supplement : official journal of the International Society of Hypertension

Content:

Date:

2008-09-01

Authors:

Dzekem BS Kacou JB Abanda M Kramoh E Yapobi Y Kingue S Kengne AP Dzudie A

Journal:

Cardiovascular journal of Africa

Content:

Date:

2017-09-01

Authors:

Katya L. Masconi Eric Brian Faragher Tandi E. Matsha Rajiv T. Erasmus Andre P. Kengne

Journal:

PLOS ONE

Content:

Date:

2019-02-07

Authors:

Caleyachetty R Kengne AP Muennig P Rutter H Echouffo-Tcheugui JB

Journal:

Obesity research & clinical practice

Content:

Date:

2016-03-01

Authors:

Matsha TE Soita DJ Hassan SM Erasmus RT Kengne AP

Journal:

Nephrology (Carlton, Vic.)

Content:

Date:

2014-10-01

Authors:

Dzudie A Fomo MF Teuwafeu DG Nkoke C Kenfack A Bonghaseh DT Ekaney D Tantchou A Tantchou C Ngoa LSE Kengne AP Choukem SP

Journal:

The Pan African medical journal

Content:

Date:

2020-10-01

Authors:

Ameh OI Kengne AP Jayne D Bello AK Hodkinson B Gcelu A Okpechi IG

Journal:

Lupus

Content:

Date:

2016-03-01

Authors:

Pandian JD William AG Kate MP Norrving B Mensah GA Davis S Roth GA Thrift AG Kengne AP Kissela BM Yu C Kim D Rojas-Rueda D Feigin VL

Journal:

Neuroepidemiology

Content:

Date:

2017-08-01

Authors:

Barthelemy Kuate Defo Jean Claude Mbanya Jean-Claude Tardif Olugbemiga Ekundayo Sylvie Perreault Louise Potvin Robert Cote Andre Pascal Kengne Simeon Pierre Choukem Felix Assah Samuel Kingue Lucie Richard Roland Pongou Katherine Frohlich Jude Saji Pierre Fournier Eugene Sobngwi Valery Ridde Marie-Pierre Dubé Simon De Denus Wilfred Mbacham Jean-Philippe Lafrance Dickson Shey Nsagha Warner Mampuya Anastase Dzudie Lyne Cloutier Christina Zarowsky Agatha Tanya Paul Ndom Marie Hatem Evelyne Rey Louise Roy Roxane Borgès Da Silva Christian Dagenais David Todem Robert Weladji Dora Mbanya Elham Emami Zakariaou Njoumemi Laurence Monnais Carl-Ardy Dubois

Journal:

JMIR Research Protocols

Content:

Date:

2017-05-29

Authors:

Noumegni SR Bigna JJ Ama Moor Epse Nkegoum VJ Nansseu JR Assah FK Jingi AM Guewo-Fokeng M Leumi S Katte JC Dehayem MY Mfeukeu Kuate L Sobngwi E

Journal:

BMJ open

Content:

Date:

2017-08-01

Authors:

Dzudie A Dzekem BS Ojji DB Kengne AP Mocumbi AO Sliwa K Thienemann F

Journal:

Cardiovascular diagnosis and therapy

Content:

Date:

2020-04-01

Authors:

Kaze FF Kengne AP Djalloh AM Ashuntantang G Halle MP Menanga AP Kingue S

Journal:

The Pan African medical journal

Content:

Date:

2014-01-01

Authors:

Tandi E Matsha Andre-Pascal Kengne Yandiswa Y Yako Gloudina M Hon Mogamat S Hassan Rajiv T Erasmus

Journal:

Content:

BACKGROUND: The proposed waist-to-height ratio (WHtR) cut-off of 0.5 is less optimal for cardiometabolic risk screening in children in many settings. The purpose of this study was to determine the optimal WHtR for children from South Africa, and investigate variations by gender, ethnicity and residence in the achieved value. METHODS: Metabolic syndrome (MetS) components were measured in 1272 randomly selected learners, aged 10-16 years, comprising of 446 black Africans, 696 mixed-ancestry and 130 Caucasians. The Youden's index and the closest-top-left (CTL) point approaches were used to derive WHtR cut-offs for diagnosing any two MetS components, excluding the waist circumference. RESULTS: The two approaches yielded similar cut-off in girls, 0.465 (sensitivity 50.0, specificity 69.5), but two different values in boys, 0.455 (42.9, 88.4) and 0.425 (60.3, 67.7) based on the Youden's index and the CTL point, respectively. Furthermore, WHtR cut-off values derived differed substantially amongst the regions and ethnic groups investigated, whereby the highest cut-off was observed in semi-rural and white children, respectively, Youden's index0.505 (31.6, 87.1) and CTL point 0.475 (44.4, 75.9). CONCLUSION: The WHtR cut-off of 0.5 is less accurate for screening cardiovascular risk in South African children. The optimal value in this setting is likely gender and ethnicity-specific and sensitive to urbanization.

Date:

Authors:

Kim Anh Nguyen Nasheeta Peer Anniza de Villiers Barbara Mukasa Tandi E. Matsha Edward J. Mills Andre Pascal Kengne

Journal:

Content:

Objectives. We determined metabolic syndrome (MetS) prevalence and assessed the agreement between different diagnostic criteria in HIV-infected South Africans. Method. A random sample included 748 HIV-infected adult patients (79% women) across 17 HIV healthcare facilities in the Western Cape Province. MetS was defined using the Joint Interim Statement (JIS 2009), International Diabetes Federation (IDF 2005), and Adult Treatment Panel III (ATPIII 2005) criteria. Results. Median values were 38 years (age), 5 years (diagnosed HIV duration), and 392 cells/mm3 (CD4 count), and 93% of the participants were on antiretroviral therapy (ART). MetS prevalence was 28.2% (95%CI: 25–31.4), 26.5% (23.3–29.6), and 24.1% (21–27.1) by the JIS, IDF, and ATPIII 2005 criteria, respectively. Prevalence was always higher in women than in men (all p<0.001), in participants with longer duration of diagnosed HIV (all p≤0.003), and in ART users not receiving 1st-line regimens (all p≤0.039). The agreement among the three criteria was very good overall and in most subgroups (all kappa≥0.81). Conclusions. The three most popular diagnostic criteria yielded similarly high MetS prevalence in this relatively young population receiving care for HIV infection. Very good levels of agreement between criteria are unaffected by some HIV-specific features highlighting the likely comparable diagnostic utility of those criteria in routine HIV care settings.

Date:

2017-01-01

Authors:

Mateen FJ Kanters S Kalyesubula R Mukasa B Kawuma E Kengne AP Mills EJ

Journal:

Journal of hypertension

Content:

Date:

2013-07-01

Authors:

Owolabi M Olowoyo P Miranda JJ Akinyemi R Feng W Yaria J Makanjuola T Yaya S Kaczorowski J Thabane L Van Olmen J Mathur P Chow C COUNCIL Initiative

Journal:

Hypertension (Dallas, Tex. : 1979)

Content:

Date:

2016-10-01

Authors:

Katte JC Djoumessi R Njindam G Fetse GT Dehayem M Kengne AP

Journal:

The Pan African medical journal

Content:

Date:

2015-11-01

Authors:

Yadgir S Johnson CO Aboyans V Adebayo OM Adedoyin RA Afarideh M Alahdab F Alashi A Alipour V Arabloo J Azari S Barthelemy CM Benziger CP Global Burden of Disease Study 2017 Nonrheumatic Valve Disease Collaborators

Journal:

Circulation

Content:

Date:

2020-03-01

Authors:

Mohsen Mazidi Andre Pascal Kengne Dimitri P. Mikhailidis Peter P. Toth Kausik K. Ray Maciej Banach

Journal:

Content:

Abstract Aim To investigate the association of major dietary patterns with glucose and insulin homeostasis parameters in a large American sample. The association between dietary patterns (DP) derived via principal components analysis (PCA), with glucose/insulin homeostasis parameters was assessed. The likelihood of insulin resistance (IR) across the DPs quarters was also explored. Method The United States National Health and Nutrition Examination Survey (NHANES) participants during 2005–2012 were included if they underwent measurement of dietary intake as well as glucose and insulin homeostasis parameters. Analysis of covariance (ANCOVA) and adjusted logistic and linear regression models were employed to account for the complex survey design and sample weights. Results A total of 24,182 participants were included; 48.9% (n = 11,815) were men. Applying PCA revealed three DP (56.8% of variance): the first was comprised mainly of saturated fat (SFA), total fat, mono-unsaturated fatty acids (MUFA) and carbohydrate (CHO); the second is highly enriched with vitamins, trace elements and dietary fiber; and the third was composed of polyunsaturated fatty acids (PUFA), cholesterol and protein. Among the total population, after adjustment for age, sex, race, C-reactive protein, smoking, and physical activity, glucose homeostasis factors, visceral adiposity index and lipid accumulation product improved across the quarters of the first and third DP; and a reverse pattern with the second DP. The same trend was observed for the non-diabetic subjects. Moreover, subjects with higher adherence to the first and third DP had higher likelihood for developing IR, whereas there was a lower likelihood for the second DP. Conclusion This study shows that the DP heavily loaded with CHO, SFA, PUFA, protein, total fat and MUFA as well as high-cholesterol-load foods is associated with impaired glucose tolerance; in contrast, the healthy pattern which is high in vitamins, minerals and fiber may have favourable effects on insulin sensitivity and glucose tolerance.

Date:

2017-01-01

Authors:

Anastase, Dzudie Bonaventure, Suiru Dzekem Martin, Leopold, Ndemnge Aminde Martin, Abanda Karen, Sliwa Cabral, Tantchou Tchoumi Ana, O Mocumbi Andre, Pascal Kengne Friedrich, Thienemann

Journal:

Content:

Date:

2018-01-01

Authors:

NCD Risk Factor Collaboration (NCD-RisC)

Journal:

eLife

Content:

Date:

2016-07-01

Authors:

Mazidi M Cicero AF Kengne AP Banach M

Journal:

Angiology

Content:

Date:

2017-12-01

Authors:

Lekoubou A Matsha TE Sobngwi E Kengne AP

Journal:

BMC research notes

Content:

Date:

2014-03-01

Authors:

Jillian Hill Nasheeta Peer Deborah Jonathan Mary Mayige Eugene Sobngwi Andre Pascal Kengne

Journal:

International Journal of Environmental Research and Public Health

Content:

Date:

2020-04-21

Authors:

Dzudie A Menanga A Hamadou B Kengne AP Atchou G Kingue S

Journal:

European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology

Content:

Date:

2006-04-01

Authors:

Masconi KL Matsha TE Erasmus RT Kengne AP

Journal:

PloS one

Content:

Date:

2015-09-01

Authors:

Mazidi M Rezaie P Vatanparast H Kengne AP

Journal:

European journal of clinical investigation

Content:

Date:

2016-12-01

Authors:

Awah PK Kengne AP Fezeu LL Mbanya JC

Journal:

Health education research

Content:

Date:

2007-09-01

Authors:

Mogueo A Echouffo-Tcheugui JB Matsha TE Erasmus RT Kengne AP

Journal:

BMC nephrology

Content:

Date:

2015-07-01

Authors:

Halle MP Takongue C Kengne AP Kaze FF Ngu KB

Journal:

BMC nephrology

Content:

Date:

2015-04-01

Authors:

Jean Jacques Noubiap, MD Jean Joel Bigna, MD Jobert Richie Nansseu, MD Ulrich Flore Nyaga, MD Eric Vounsia Balti, MD Justin B Echouffo-Tcheugui, MD André Pascal Kengne, MD

Journal:

Content:

Summary: Background: The burden of dyslipidaemia in Africa remains inadequately characterised. We aimed to estimate the prevalence of dyslipidaemia in African adults from hospital-based and community-based studies. Methods: In this systematic review and meta-analysis, we searched MEDLINE via PubMed, Embase, African Journals Online, and African Index Medicus for studies published between Jan 1, 1980, and July 31, 2017, without language restriction. We assessed methodological quality of all cross-sectional studies reporting on the prevalence of elevated concentrations of total cholesterol, LDL cholesterol, or triglycerides, or low concentrations of HDL cholesterol in adults residing in African countries. We excluded reports on Africans living outside Africa, studies of individuals selected on the basis of existing dyslipidaemia or those including children and adolescents, and case series with a small sample size. The most frequently used cutoffs in the included studies were chosen for the subgroup analysis. We used random-effect model meta-analysis to derive the pooled prevalence of elevated total cholesterol, low HDL cholesterol, elevated LDL cholesterol, and elevated triglyceride concentrations. This study is registered with PROSPERO, number CRD42014015376. Findings: 181 studies (309 207 participants) were included in the meta-analysis. The pooled prevalence of dyslipidaemia in the general population from population-based studies was 23·6% (95% CI 18·4–29·2) for elevated concentrations of total cholesterol with a cutoff of at least 5·2 mmol/L, 41·1% (33·0–49·4) for low concentrations of HDL cholesterol with a cutoff of less than 1·0 mmol/L, 25·7% (16·2–36·6) for elevated concentrations of LDL cholesterol with a cutoff of at least 3·3 mmol/L, and 16·5% (11·8–21·6) for elevated concentrations of triglycerides with a cutoff of at least 1·7 mmol/L. Interpretation: The prevalence of dyslipidaemia is high in the general adult population in Africa. Ongoing efforts to reduce cardiovascular diseases in Africa should integrate effective detection and treatment of dyslipidaemia. Funding: None.

Date:

2018-01-01

Authors:

Chivese T Mahmoud W Magodoro I Kengne AP Norris SA Levitt NS

Journal:

BMJ open

Content:

Date:

2016-12-01

Authors:

Kengne AP

Journal:

Cardiovascular journal of Africa

Content:

Date:

2012-02-01

Authors:

Lekoubou A Nkoke C Dzudie A Kengne AP

Journal:

Journal of the neurological sciences

Content:

Date:

2015-02-01

Authors:

Wonkam A Kengne AP

Journal:

The Lancet. Haematology

Content:

Date:

2021-09-01

Authors:

Djoumessi RN Noubiap JJ Kaze FF Essouma M Menanga AP Kengne AP Mbanya JC Sobngwi E

Journal:

BMC research notes

Content:

Date:

2016-03-01

Authors:

Mark Hamer Emmanuel Stamatakis Mika Kivimäki Andre Pascal Kengne G. David Batty

Journal:

Psychosomatic Medicine

Content:

Date:

2010-11-01

Authors:

S. Czernichow S. Van Dieren A. Pascal Kengne J. Chalmers M. Marre S. Zoungas

Journal:

Diabetes & Metabolism

Content:

Date:

2011-03-01

Authors:

Yako YY Guewo-Fokeng M Balti EV Bouatia-Naji N Matsha TE Sobngwi E Erasmus RT Echouffo-Tcheugui JB Kengne AP

Journal:

Diabetes research and clinical practice

Content:

Date:

2016-01-01

Authors:

Ngueta G Kengne AP

Journal:

Biological trace element research

Content:

Date:

2016-06-01

Authors:

Kengne AP Czernichow S Stamatakis E Hamer M Batty GD

Journal:

Journal of hepatology

Content:

Date:

2012-07-01

Authors:

Adom T Puoane T De Villiers A Kengne AP

Journal:

BMJ open

Content:

Date:

2017-01-01

Authors:

Lekoubou A Debroy K Kwegyir-Aggrey A Bonilha L Kengne AP Chinchilli VM

Journal:

Epilepsy & behavior : E&B

Content:

Date:

2021-05-01

Authors:

NCD Risk Factor Collaboration (NCD-RisC)

Journal:

Lancet (London, England)

Content:

Date:

2016-04-01

Authors:

Peer N George J Lombard C Steyn K Levitt N Kengne AP

Journal:

BMC nephrology

Content:

Date:

2020-08-01

Authors:

Matsha TE Macharia M Yako YY Erasmus RT Hassan MS Kengne AP

Journal:

European journal of preventive cardiology

Content:

Date:

2013-08-01

Authors:

Mazidi M Huybrechts I Kengne AP

Journal:

European journal of clinical nutrition

Content:

Date:

2019-06-01

Authors:

Halle MP Kengne AP Ashuntantang G

Journal:

Renal failure

Content:

Date:

2009-01-01

Authors:

Andre Pascal Kengne Rajiv T. Erasmus Naomi S. Levitt Tandi E. Matsha

Journal:

Primary Care Diabetes

Content:

Date:

2017-04-01

Authors:

Pefura-Yone EW Kuaban C Assamba-Mpom SA Moifo B Kengne AP

Journal:

The clinical respiratory journal

Content:

Date:

2014-02-01

Authors:

Feigin VL Mensah GA Norrving B Murray CJ Roth GA GBD 2013 Stroke Panel Experts Group

Journal:

Neuroepidemiology

Content:

Date:

2015-10-01

Professor
Andre Pascal Kengne

Related fellows

Associate Professor Yaya Kassogue

Dr Zivai Nenguke

Ms Emily Awuor Abuonji

Project Title

EDCTP Project

EDCTP Program

EDCTP Project Call

Project Objectives

Study Design

Project Summary

Host Organisation

Current Organisation

Current Job Title

Biography

Publications

Professor Andre Pascal Kengne

Related fellows

Associate Professor Yaya Kassogue

Dr Zivai Nenguke

Ms Emily Awuor Abuonji

Project Title

EDCTP Project

EDCTP Program

EDCTP Project Call

Project Objectives

Study Design

Project Summary

Host Organisation

Current Organisation

Current Job Title

Biography

Publications

Professor
Andre Pascal Kengne