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Agnes Gatarayiha

Rwanda

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Project Title

Capacity Building for Female Scientists in East Africa ( CaFe-SEA)

EDCTP Project

PSIA2020AGDG-3318

EDCTP Program

EDCTP2

EDCTP Project Call

Female PhD Fellowship (PSIA Fellows)

Project Objectives

There is an increased prevalence of periodontitis in patients with hypertension, and oral microbiome dysbiosis during periodontitis might be a factor contributing to hypertension. To assess whether periodontitis constitute a risk factor with hypertension among adults in Rwanda

Study Design

Quantitative

Project Summary

Cardiovascular disease causes majority of deaths worldwide, with 11.3% of these occurring in Africa. In Rwanda, 36% of total deaths are due to noncommunicable diseases. Hypertension, is a leading risk factor of cardiovascular disease. Pharmacological treatments are currently failing to treat the hypertension chronically. Hypertension treatment is thus increasing the burden of finance on health systems worldwide and thus alternative approaches to prevention and treatment are urgently required. Several hypotheses exist for this, including that periodontal disease induces the entrance of bacteria into circulatory system, in turn activating a host systemic inflammatory response. A healthy oral microbiome is also essential for promoting systemic health while oral dysbiosis may lead to hypertension.

Host Organisation

Department Institution Country
Public Health University of Rwanda RW