Project Title

Clinical trials in HIV/AIDS in Africa: Should they routinely control for mental health factors?

EDCTP Project Call

Senior Fellowship (SF)

Project Objectives

The study aimed to answer the following questions: 1. What is the prevalence of mental health problems associated with major depressive disorders (MDD) and maladaptive coping style (MACS) among HIV-infected patients in Uganda, and what is the incidence of MDD in HIV/AIDS? 2. Do mental health problems associated with MDD and MACS significantly impact on HIV disease progression in an Ugandian socio-cultural environment including through non-adherence to ART? 3. What would be the potential impact of MDD and MACS mental health covariates on HIV disease progression on the DART trial results under a range of possible differential treatment effects in the subgroups of patients with and without psychological problems?

Study Design

Prevalence study of mental health among clinical trials participants in HIV/AIDS

Host Organisation

Results & Outcomes

Current Organisation

Current Job Title

Biography

Publications