Project Title

Infectious Diseases Data Observatory (IDDO), University of Oxford, United Kingdom

EDCTP Project Call

EDCTP Clinical Research & Development Fellowship (R&D F)

Project Objectives

Training Plan Goal: To acquire advanced knowledge and skills in clinical trials design, data analysis and data sharing, operations for implementation of research action and development in Africa. Objectives • Gain skills in clinical trial design • Gain skills in statistics, sample size calculation and data analysis • Gain skills in protocol development and systematics reviews • Gain skills in online English course and have a direct contact with community of researchers • Enhance skills in clinical trial toolkits on antimalarial drug • Acquire skills in other relevant training opportunities

Study Design

During the fellowship in the host organization, I will carry out following activities: • English courses • Training on clinical trials design at IDDO • Training on statistics, sample size calculation and data analysis at IDDO • Training on protocol development and systematics reviews at IDDO • Training on clinical trial toolkits on antimalarial drug at IDDO • Training on other relevant training opportunities at IDDO(e.g: Database design, introduction to R and Stata, Geospatial analysis using ArcGIS etc) • Training modules on good practice in data management, ethics data and anti-malaria toolkits of IDDO

Project Summary

The development of human research capabilities is a serious need for Sub-Saharan African countries in clinical research on poverty-related diseases such as malaria, HIV, tuberculosis and NTDs. To be leaders in clinical research, researchers in Sub-Saharan Africa need to develop and strengthen their sustainable research skills in diagnostics, drugs and vaccines. As part of EDCTP's Clinical Trials Capacity Building Scholarship Program, we are proposing activities for 2 work packages, training plan and re-integration plan. The first work package is Training Plan. We have activities following which are: (i) IDDO-ICMR training program before the placement at IDDO, (ii) Clinical trial design at IDDO (including designing clinical research and biostatistics), (iii) Statistics, sample size calculation and data analysis, (iv) Protocol development, systematic review, writing and publishing research papers at IDDOwill be carried out, (v) Good practices in data management, data analysis ,data ethics and anti-malarial toolkits of IDDO and (vi) Other opportunities training (e.g: Database design, introduction to MySQ, R and Stata, Geospatial analysis using ArcGIS etc) will be performed. Centre MURAZ is a biomedical Centre dedicated to research and control of tropical diseases and malaria. It is experienced in evaluating strategies for prevention of Malaria, HIV, and Meningococcal disease through clinical trials. Centre MURAZ is conducting a Phase II trial on Ebola vaccine and ACHIV project. In July 2018, Centre MURAZ was merged with 2 other research Centres (CNRFP and CRSN) to form the National Institute of Public Health (INSP) of Burkina. INSP is the lead coordinator of these centers with mission to research, to prevent and to control diseases in Burkina Faso and also training. The second work package is Re-integration Plan. To ensure the application and transfer of advanced knowledges and skills learnt at IDDO, I will implement in Centre MURAZ, the following activities: (i) Visit of Centre MURAZ by IDDO team in order to strengthen South-North partnership between Centre MURAZ and IDDO, (ii) Three (03) comprehensive dissemination workshops will be organized in Centre MURAZ. I will develop the training modules during my placement at IDDO, under the supervision of both my host and home mentors; (iii): Continuous methodological support to Centre MURAZ young researchers involved in MSc or PhD programs will be done; (iv) Development and submition a specific efficacy study protocol on malaria in order to increase the number of protocols for further researches, (v) Building of strategic partnership with other research Centres in Burkina Faso and West africa. Both the training workshops and the continuous methodological supports, will be opened to applicants from other research centres in Burkina Faso whenever possible.

Host Organisation

Current Organisation

Infectious Diseases Data Observatory, University of Oxford

Current Job Title

EDCTP-Fellow/ Visiting Researcher

Biography

Publications