This project was coordinated by the ICGEB and implemented in partnership with reference testing laboratories in Africa. ICGEB Member States, Cameroon, Ethiopia, Kenya, and Nigeria, have taken part in a pilot study to assess the efficacy of a novel diagnostic tool in diverse settings. Dr Joseph Fokam (TMA2015CDF1027) was the local PI in Cameroon.
This pilot study, performed during the period September 2020-May 2021, contributed to the accuracy in detecting SARS-CoV-2 in resource-limited settings. It evaluated the diagnostic performance of RT-LAMP in terms of intrinsic (sensitivity, specificity) and extrinsic (positive and negative predictive values) characteristics according to SARS-CoV-2 viral load estimates provided by the conventional RT-qPCR in four LMICs of Sub-Saharan Africa. Results from the study show that RT-LAMP represents a formidable alternative to RT-qPCR. New England BioLabs freely contributed its LAMP technology to the study, and the Bill & Melinda Gates Foundation funded the project (INV – 022816).
To learn more about this exciting project visit https://www.youtube.com/watch?v=F-xSlulkN-4
We are delighted to announce that the 13th edition of the EDCTP Forum will be celebrated on 5-9 April 2027, at IFEMA Palacio Municipal in Madrid, Spain.
The event will be co-hosted by the Instituto de Salud Carlos III (ISCIII) under the Spanish Ministry of Science, Innovation and Universities and the Fundación CSAI (FCSAI) under the Ministry of Health, and is co-organised by Global Health EDCTP3 and the EDCTP Association.
Over the past two decades, the biennial European & Developing Countries Clinical Trials Partnership (EDCTP) Forum has evolved to become a cornerstone event for global health research, bringing together leading voices advancing the fight against infectious diseases in sub-Saharan Africa. It showcases the latest scientific breakthroughs, highlights impactful capacity-building efforts, and creates a space for vibrant cross-regional collaboration.
The EDCTP Forum 2027 expects to convene 1,500 participants and stakeholders, from researchers, universities and clinicians to governments, regional bodies, civil society, regulators, and public and private R&D partners, drawing participation primarily from Africa and Europe.
Botswana-born scientist Dr Tuelo Mogashoa, a PhD Fellow in the ‘Addressing Gender and Diversity Regional Gaps in Clinical Research Capacity’ (TAGENDI) programme, has successfully defended her PhD in Molecular Biology (Tuberculosis Genomics) at Stellenbosch University. Her virtual oral examination, held on 12 January 2025, marked the culmination of years of research and training.
Her doctoral thesis, titled “Rifampicin- resistant tuberculosis: an emerging threat to human health in Botswana,” addresses one of the most pressing challenges in TB control.
Dr Mogashoa is the first of seven PhD fellows from the inaugural TAGENDI cohort to complete her doctoral studies. The TAGENDI fellowship, implemented under the Trials of Excellence in Southern Africa (TESA) Network, is part of a dedicated PhD fellowship scheme launched by EDCTP2 in 2020 to support women in health research across sub-Saharan Africa. Coordinated by the EDCTP Networks of Excellence, the initiative received funding from the UK National Institute for Health and Care Research (Department of Health and Social Care).
As part of her PhD requirements, Dr Mogashoa was expected to produce four manuscripts, with at least two accepted in peer-reviewed journals. She has exceeded this requirement, publishing three peer-reviewed articles from her doctoral work, with a fourth manuscript currently under review.
Her journey highlights the transformative impact of long-term investment in research training, mentorship, and gender equity. As she moves into the next phase of her career, her work promises to make a meaningful contribution to improving TB diagnosis, treatment, and control.
Prof. Novel Chegou, EDCTP Senior Fellow and Acting Head of the Division of Immunology at the Faculty of Medicine and Health Sciences, Stellenbosch University, has been elected as a Fellow of the African Academy of Sciences. This important achievement recognises his scientific leadership and impactful research on tuberculosis, particularly his work on biomarkers to improve diagnosis and patient care in resource-limited settings.
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