UNAIDS Press Release: United Nations Secretary-General calls for a greater focus on ending inequalities to end AIDS
Forty years since the first AIDS cases were reported and just weeks before the United Nations General Assembly High-Level Meeting on AIDS, the United Nations Secretary-General has released a new report with recommendations and targets to get the world on track to end AIDS
NEW YORK, 30 April 2021—The United Nations Secretary-General, António Guterres, has warned that despite intensive action and progress made against HIV in some places and population groups, HIV epidemics continue to expand in others and issued a set of 10 key recommendations.* If followed by all countries, this will end the AIDS pandemic as a public health threat by 2030 as part of the Sustainable Development Goals. In a new report, Addressing inequalities and getting back on track to end AIDS by 2030, the United Nations Secretary-General urges the world to address the inequalities that are slowing progress.
“It is imperative to break out of an increasingly costly and unsustainable cycle of achieving some progress against HIV but ultimately not enough to bring about an end to the pandemic,” said Mr Guterres in the report. “Inequalities are the key reason why the 2020 global targets were missed. By ending inequalities, transformative outcomes can be achieved for people living with HIV, communities and countries.”
The global targets set out in the General Assembly’s 2016 Political Declaration on Ending AIDS were missed by a long way, allowing the AIDS pandemic to grow in many regions and countries. The staggering 1.7 million new HIV infections that occurred in 2019 are more than three times higher than the 2020 target of less than 500 000 new infections. In addition, the 690 000 AIDS-related deaths in 2019 far exceed the 2020 target of reducing deaths to fewer than 500 000 a year.
“Ending AIDS as a public health threat by 2030 is still within reach—many countries are showing that rapid progress against HIV is possible when evidence-informed strategies and human rights-based approaches are adopted,” said UNAIDS Executive Director Winnie Byanyima. “But it requires bold political leadership to challenge and address the social injustices and inequalities that continue to make certain groups of people and entire communities highly vulnerable to HIV infection.”
The report notes that COVID-19 has caused additional setbacks. The United Nations Secretary-General warned that COVID-19 is not an excuse for missing AIDS targets, but rather a stark warning to the countries that they can no longer afford to underinvest in pandemic preparedness and responses.
At the same time, the COVID-19 pandemic has underscored the many spill-over benefits of HIV investments in health and development. Community-led service delivery pioneered by the HIV response is helping to overcome the extraordinary impediments created by COVID-19.
The set of 10 recommendations to get the world back on track include: addressing inequalities and reaching all people living with or at risk of HIV infection to reduce the annual new HIV infections to under 370 000 and annual AIDS-related deaths to under 250 000 by 2025; prioritizing HIV prevention to ensure that 95% of people at risk of HIV infection have access to effective HIV prevention options by 2025; and eliminating new HIV infections among children.
The report underscores that addressing social and structural factors that perpetuate inequalities is key. It highlights, for example, how gender inequality, underpinned by harmful gender norms, restricts women’s use of HIV and sexual and reproductive health services by perpetuating gender-based violence and limiting decision-making power, including the ability of women and girls to refuse unwanted sex, negotiate safer sex and mitigate HIV risk. It also shows how vulnerable, marginalized and criminalized communities, such as gay men and other men who have sex with men, people who use drugs, sex workers, transgender people, prisoners and migrants, also remain at higher risk of HIV infection than the general population because they are not receiving essential information and HIV treatment, prevention and care services. The United Nations Secretary-General describes how communities of people living with, at risk of and affected by HIV are the backbone of the HIV response. Initiatives led by people living with HIV, women, key populations, young people and other affected communities have identified and addressed key inequalities and service gaps, advocated for the rights of their constituents and expanded the reach, scale and quality of health services. In the report, Mr Guterres applauds UNAIDS’ recently adopted Global AIDS Strategy 2021–2026: End Inequalities, End AIDS.
“The lessons from the countries, cities and communities that successfully fast-tracked their HIV responses over the last five years are at the heart of the UNAIDS Global AIDS Strategy 2021–2026,” said Mr Guterres. “The global AIDS community and UNAIDS have used an inequalities lens to develop the strategy, with new targets that are ambitious, granular and tailored to reach the furthest behind first.”
The report comes 25 years after the creation of UNAIDS and describes how COVID-19 has exposed social inequalities and health system weaknesses. The United Nations Secretary-General says that the world should leverage the experience from responding to the AIDS pandemic to strengthen health systems across the world and improve pandemic preparedness. He also calls for enhanced global solidarity to close the HIV resource gap and increase annual HIV investments in low- and middle-income countries to US$ 29 billion by 2025.
For more information and the full report visit https://hlm2021aids.unaids.org/sg-report/
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Prof. George Boateng Kyei: Advancing Hiv Research In Africa
In his EDCTP-GSK Senior Fellowship, Professor George Boateng Kyei of the Noguchi Memorial Institute for Medical Research, University of Ghana, has not only advanced the search for an HIV cure but also strengthened research capacity across Ghana and the broader African region.
Addressing HIV persistence
HIV remains a pressing public health issue in Africa, with persistent challenges hindering the quest for a cure. This fellowship project focused on one such challenge: the virus’s ability to remain dormant within resting CD4+ T cells, even among individuals receiving antiretroviral therapy (ART). By exploring the innovative “shock and kill” approach, the research aimed to reactivate latent HIV and target infected cells for destruction. A notable scientific achievement was the identification and confirmation of three novel epigenetic compounds capable of reactivating latent HIV from virologically suppressed individuals. These findings pave the way for future studies in animal models, with the potential to transition into clinical trials aiming at finding a cure for HIV.
Strengthening research infrastructure
The establishment of a drug screening platform at the University of Ghana stands out as a long-term asset for HIV drug discovery and cure research. Additionally, the project introduced regular viral load monitoring for a substantial cohort of patients—an essential practice previously not standard in Ghana. The data generated from this monitoring has been instrumental in shaping national HIV treatment policies and improving patient care.
Furthermore, the project developed a biobank and a well-characterised cohort of HIV-infected adults, providing invaluable resources for ongoing and future HIV cure research. Insights gathered from patients regarding their perceptions of HIV cure research will inform the design and conduct of subsequent studies in Ghana and across Africa.
Training the next generation of researchers
The impact of the fellowship extends beyond laboratory accomplishments; it has significantly influenced research training and career development. The fellowship helped nurture the growth of junior scientists, many of whom have evolved into independent research leaders, securing competitive grants and fellowships, such as the IAS Research-for-Cure Academy and NIH R21. They have presented their findings at prestigious international conferences, including the African Virology Congress and the American Society of Tropical Medicine and Hygiene (ASTMH).
Post-doctoral fellows have notably received fellowships from esteemed international programmes, such as the Science by Women Fellowship and the NIH CFAR Africure award, showcasing their growing prominence in the research community.
Recognition and awards
Professor Kyei’s mentorship has not gone unnoticed; in April 2024, he received special recognition from the University of Ghana’s Centre for Gender Studies and Advocacy (CEGENSA) for his outstanding mentorship of female academics—an honour highlighted by nominations from his own mentees. The project also celebrated the achievements of its team members, with one post-doc winning Best Senior Research Fellow at the 2024 NMIMR Awards and research assistants earning accolades at the 2024 African Virologist Conference.
Professor Kyei’s research has led to significant international visibility, with his team members winning travel awards to attend prestigious conferences, including the Keystone Symposium and the African Virology Congress. These opportunities have allowed them to present their findings and collaborate with global experts in the field.
Expanding horizons
The EDCTP-GSK Senior Fellowship grant has facilitated the groundwork for additional projects, including a newly awarded Fogarty grant aimed at enhancing HIV basic science and cure research training at the University of Ghana. This grant will train 17 researchers over the next 5 years, further strengthening the research landscape in Ghana.
As the team looks to the future, plans are in place to expand research into HIV reservoir characteristics among virologically suppressed patients across Ghana. This extension not only continues the momentum generated by the EDCTP grant, but also reinforces Ghana’s position as a leader in HIV cure research in Africa and contributes to the global effort to eradicate HIV.
Save The Date! Communications Workshop At The Edctp 2025 Forum
Dear Colleague,
Are you attending the EDCTP 2025 forum in Kigali (Rwanda)?
Don't miss the Communications workshop on Thursday 19 June (15:30 - 17:30 Rwanda time) in room MH3.
The topic of the workshop will be: "From good to great: Mastering communication skills for impactful science
Best,
The EDCTP team.
Call For Proposals: Panel Sessions At Science Forum South Africa 2025
Dear Stakeholder
Science Forum South Africa 2025 (SFSA 2025) will take place from 24 to 28 November 2025 at the CSIR International Convention Centre (CSIR ICC) in Pretoria, South Africa. This year marks the tenth edition of SFSA, celebrating a decade of igniting vibrant discussions on the role of science in society. The Forum brings together stakeholders from the scientific community, government, industry, and civil society.
We are pleased to invite proposals from individuals and institutions to convene panel sessions as part of the SFSA 2025 programme. These sessions should align with the Forum's theme and sub-themes, and provide an opportunity to engage diverse perspectives in critical conversations.
FORUM THEME
Igniting Conversations: Placing Science, Technology, and Innovation at the Centre of Government, Education, Society, and Industry
SUB-THEMES
- Financing for Science, Technology and Innovation (STI)
- Science and Society Nexus (Agriculture, Health, Climate Change, Just Energy Transition)
- Building Research Capabilities for Africa (STISA 2024)
- The Role of Science Diplomacy
- Emerging Industry – The Role of Disruptive Technologies
- Science Journalism and Science Communication
- Entrepreneurship and Innovation
HOW TO SUBMIT
The deadline for proposal submissions is 21 July 2025.
SFSA 2025 is proudly co-hosted by the South African Department of Science, Technology and Innovation (DSTI) and the Science Diplomacy Capital for Africa (SDCfA) initiative.
We look forward to your participation in shaping the dialogue at SFSA 2025.
Best regards
The SFSA 2025 Organising Committee