World TB Day puts the spotlight on tuberculosis (TB), a poverty-related infectious disease of epidemic proportions. Currently, it causes more deaths than any other infectious disease, mostly in low- and middle-income countries. Every year, an estimated 10 million people fall ill; in 2019, 1.4 million people died from TB. All members of the United Nations committed to ending TB as an epidemic by 2030. However, the 2020 WHO progress report concluded that the world is not on schedule to achieve the 2022 targets. The COVID-19 pandemic even threatens to reverse recent progress towards global TB targets. Chronic global underfunding of TB research means that cheap, accessible point-of-care tests, better vaccines and simple, short treatment regimens are lacking. Ending TB depends on the development and rapid uptake of new tools and innovation.
“Our steady commitment to fight TB has led to a growing R&D portfolio of grants on novel diagnostics, more patient-friendly treatments, and experimental vaccines for pre-and post-exposure use – especially targeting vulnerable populations. Moreover, we have invested in international coordination of TB vaccine R&D, and preparation of ground for a new global TB vaccine roadmap. EDCTP is convinced a concerted global R&D effort will end TB.”
Dr Michael Makanga, EDCTP Executive Director
Visit https://www.edctp.org/news/world-tb-day-promise-ending-tb-epidemic/ to learn more about EDCTPs efforts to end TB.
We are delighted to announce that the 13th edition of the EDCTP Forum will be celebrated on 5-9 April 2027, at IFEMA Palacio Municipal in Madrid, Spain.
The event will be co-hosted by the Instituto de Salud Carlos III (ISCIII) under the Spanish Ministry of Science, Innovation and Universities and the Fundación CSAI (FCSAI) under the Ministry of Health, and is co-organised by Global Health EDCTP3 and the EDCTP Association.
Over the past two decades, the biennial European & Developing Countries Clinical Trials Partnership (EDCTP) Forum has evolved to become a cornerstone event for global health research, bringing together leading voices advancing the fight against infectious diseases in sub-Saharan Africa. It showcases the latest scientific breakthroughs, highlights impactful capacity-building efforts, and creates a space for vibrant cross-regional collaboration.
The EDCTP Forum 2027 expects to convene 1,500 participants and stakeholders, from researchers, universities and clinicians to governments, regional bodies, civil society, regulators, and public and private R&D partners, drawing participation primarily from Africa and Europe.
Botswana-born scientist Dr Tuelo Mogashoa, a PhD Fellow in the ‘Addressing Gender and Diversity Regional Gaps in Clinical Research Capacity’ (TAGENDI) programme, has successfully defended her PhD in Molecular Biology (Tuberculosis Genomics) at Stellenbosch University. Her virtual oral examination, held on 12 January 2025, marked the culmination of years of research and training.
Her doctoral thesis, titled “Rifampicin- resistant tuberculosis: an emerging threat to human health in Botswana,” addresses one of the most pressing challenges in TB control.
Dr Mogashoa is the first of seven PhD fellows from the inaugural TAGENDI cohort to complete her doctoral studies. The TAGENDI fellowship, implemented under the Trials of Excellence in Southern Africa (TESA) Network, is part of a dedicated PhD fellowship scheme launched by EDCTP2 in 2020 to support women in health research across sub-Saharan Africa. Coordinated by the EDCTP Networks of Excellence, the initiative received funding from the UK National Institute for Health and Care Research (Department of Health and Social Care).
As part of her PhD requirements, Dr Mogashoa was expected to produce four manuscripts, with at least two accepted in peer-reviewed journals. She has exceeded this requirement, publishing three peer-reviewed articles from her doctoral work, with a fourth manuscript currently under review.
Her journey highlights the transformative impact of long-term investment in research training, mentorship, and gender equity. As she moves into the next phase of her career, her work promises to make a meaningful contribution to improving TB diagnosis, treatment, and control.
Prof. Novel Chegou, EDCTP Senior Fellow and Acting Head of the Division of Immunology at the Faculty of Medicine and Health Sciences, Stellenbosch University, has been elected as a Fellow of the African Academy of Sciences. This important achievement recognises his scientific leadership and impactful research on tuberculosis, particularly his work on biomarkers to improve diagnosis and patient care in resource-limited settings.
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