Call | Career Development Fellowship (CDF) |
Programme | EDCTP2 |
Start Date | 2017-07-01 |
End Date | 2019-12-31 |
Project Code | TMA2015CDF1027 |
Status | Active |
Evaluation of Treatment Response, Drug Resistance and HIV-1 Variability among Adolescents on First- and Second-Line Antiretroviral Therapy in Cameroon: The READY-Study
General Objectives: Among Cameroonian adolescents (10-19 years old) receiving ART, we shall monitor the therapeutic response to first- and second-line regimens, drug resistance profiling and HIV-1 genetic variability during one-year follow-up. Specific objectives: In this population of adolescents receiving ART in Cameroon, we shall: 1) Evaluate the rate of immunovirologic failure in the entire population at enrolment, month-6 and month-12 follow-up points; 2) Evaluate acquired DRMs and HIV-1 subtype distribution among those experiencing VF at enrolment, month-6 and month-12 follow-up points; 3) Evaluate the genetic variability in circulating (plasma) versus archived (cellular) viral strains among those experiencing VF at enrolment, month-6 and month-12 follow-up points; 4) Evaluate HIVDR early warning indicators (EWIs), including survival analysis, in the entire study population through out the one-year monitoring period.
Institution | Country |
---|---|
International Reference Centre Chantal Biya (CIRCB) | Cameroon |
Name | Institution | Country |
---|---|---|
Prof. Alexis Ndjolo | CIRCB | Cameroon |
Prof. Vittorio Colizzi | CIRCB | Cameroon |
Prof. Carlo-Federico Perno | University of Rome Tor Vergata | Cameroon |
Prospective, open, observational study
Prospective, open, observational study |
Type | Name | Title | University | Start Date | End Date |
---|---|---|---|---|---|
MD Thesis | Armanda Nangmo | Assessment of immuno-virological response and hiv-1 drug resistance among adolescents on antiretroviral therapy in two reference pediatric centers in Yaoundé | Faculty of Health Sciences, University of Bamenda | 02/01/2018 | 30/09/2018 |
MD Thesis | Carlson Wandum | Evaluation of treatment response, HIV drug resistance and genetic diversity in rural settings of the Centre region of Cameroon | Faculty of Health Sciences, University of Bamenda | 02/01/2018 | 30/09/2018 |
MD Thesis | Anubodem Felix | Pretreatment HIV drug resistance in the Southwest region of Cameroon | Faculty of Medicine and Biomedical Sciences, University of Yaounde I | 15/11/2017 | 30/07/2018 |
MD Thesis | Chenwi Collins | Determinants of HIV-1 drug resistance | Faculty of Medicine and Biomedical Sciences, University of Yaounde I | 15/11/2017 | 30/07/2018 |
Dentistry Thesis | Buolikeze Geh | Determinants of periodontitis among HIV-infected patients in Cameroon | Faculty of Medicine and Biomedical Sciences, University of Yaounde I | 15/11/2017 | 30/07/2018 |
Pharmacy Thesis | Odine Padimel | Pretreatment HIV drug resistance in the urban setting of the Northwest region of Cameroon | Faculty of Medicine and Biomedical Sciences, University of Yaounde I | 15/11/2016 | 30/07/2017 |
MD Thesis | Suh Emile | Pretreatment HIV drug resistance in the rural setting of the Northwest region of Cameroon | Faculty of Medicine and Biomedical Sciences, University of Yaounde I | 15/11/2016 | 30/07/2017 |
MD Thesis | Le Koungou Catherine | Feasibility study of Human identification by DNA technology | Faculty of Medicine and Biomedical Sciences, University of Yaounde I | 15/11/2016 | 30/07/2017 |
CIRCB: Chantal BIYA International Reference Centre for research on HIV/AIDS prevention and management
Head of Virology Laboratory (Chief or Service)