||Nnamdi Azikiwe University
1. The main aim of the present study is to use the rigour of a randomised controlled trial (RCT) to evaluate the impact of financial incentive and motivational interviewing on adolescents’ linkage, retention and adherence to antiretroviral therapy and HIV care in Anambra State, Nigeria.
2. Cost-effectiveness analysis alongside the cluster randomized trial will be conducted as a secondary aim to assess the cost per additional patient achieving viral suppression through the proposed intervention.
3. In-depth interview (IDI) with all the healthcare providers in the intervention arm will be conducted at the end of the study to assess their perspective on the programme’s feasibility.
1. Chukwuemeka Odimgewu Teaching Hospital, Awka (COOUTH)
2. General Hospital Onitsha (GHO)
3. General Hospital Ekwulobia (GHE)
4. General Hospital Enugwu Ukwu (GHEU)
5. Holy Rosary Hospital, Onitsha (Water side) (HRHO)
6. Nnamdi Azikiwe University Teaching Hospital (NAUTH), Nnewi (including NAUTH Extension, Nneni – NAUTH 2 and NAUTH Extension, Oba – NAUTH 3)
7. Our Lady of Lourdes, Ihiala (OLL)
8. St Charles Borromeo Hospital, Onitsha (SCB)
9. St Joseph Hospital, Adazi Nnukwu (SJH)
10. Regina Caeli Specialist Hospital, Awka (RCSH)
11. Immaculate Heart Hospital and Maternity, Nkpor (IHHM)
12. Iyi Enu Mission Hospital (IEMH)
Cluster randomized trial
1. The primary outcome for the trial will be the difference between groups in the proportion with HIV viral load (VL) suppression (≤20 copies/mL) by 12 months and 24 months.
2. The secondary outcome measure will include the average change in CD4+ count, adherence to ART (measured using pill count) and adherence to an appointment with the hospital for individual participants.