EDCTP Alumni Network

Fostering excellence and collaboration in the next generation of researchers

Call Career Development Fellowship (CDF)
Programme EDCTP2
Start Date 2018-07-01
End Date 2021-06-30
Project Code TMA2016CDF1550
Status Active

Title

Immunogenicity to cholera vaccine within a population at risk in Zambia: mapping the kinetics of immune responses over time

Objectives

• Determine cholera specific antibody titers at baseline (prior vaccination) • Determine seroconversion after 1st and 2nd doses • Asses benefits of a 2nd dose of OCV given after 4 weeks following the 1st dose • Determine if vaccine immune responses wane off at 6, 12, 24, 36, 42 or 48 months post second dose OVC

Host Organisation

Institution Country
Centre for Infectious Disease Research in Zambia (CIDRZ) Zambia

Participants

Name Institution Country
Caroline Cleopatra Chisenga Centre for Infectious Dise Zambia
Harriet Ngombe Centre for Infectious Dise Zambia

Study Design

This is a pre/post-vaccine study involving a cohort of individuals receiving an oral cholera vaccine provided by the ministry of health (MoH) in response to a cholera outbreak in the Lukanga Swamps. Volunteering eligible individuals were, consented, enrolled and the questionnaire administered.

Sites

Lukanga Swamps-Central Province of Zambia

Phd Study

Title University Start Date End Date
Mr John Mwaba University of Zambia 2018-08-01 2021-12-31

Students Supervised

Type Name Title University Start Date End Date
MSc Student Harriet Ngombe Ms University of Zambia 2019 2021

Results & Outcomes

In progress

Current Organisation

Centre for Infectious Disease Research in Zambia

Current Job Title

Research Fellow

Students Supervised

Type Name Title University Start Date End Date
MSc Student Harriet Ngombe Ms University of Zambia 2019 2021
MSc Tracy Naomi Phiri Ms University of Zambia 2019 2021
MSc Student Nawa Mukena Mr University of Zambia 2019 2021

Education

Institution Degree Year
University of Ulster, Ireland Graduate Certificate in Biomedical Sciences 2007
University of Ulster, Ireland Masters in Biomedical Sciences 2009
University of Zambia, Zambia PhD in HIV immunology 2015

Areas Of Specialisation

Diarrhoeal Diseases (DDs)

Publications

Authors:
Natasha Makabilo Laban , author
Samuel Bosomprah , author
Kalo Musukuma-Chifulo , author
Michelo Simuyandi , author
Shilpa Iyer , author
Harriet Ng'ombe , author
Mutinta Muchimba , author
Adriace Chauwa , author
Sekayi Tigere , author
Caroline Cleopatra Chisenga , author
Mwelwa Chibuye , author
Obvious Nchimunya Chilyabanyama , author
Martin Goodier , author
Roma Chilengi , author
Date:
2021-05-06
Journal:
Content:
Identifiers:
Authors:
Caroline C. Chisenga , author
Ray Borrow , editor
Samuel Bosomprah , author
Michelo Simuyandi , author
Katayi Mwila-Kazimbaya , author
Obvious N. Chilyabanyama , author
Natasha M. Laban , author
Anya Bialik , author
Valeria Asato , author
Shiri Meron-Sudai , author
Gad Frankel , author
Daniel Cohen , author
Roma Chilengi , author
Date:
2021-05-27
Journal:
PLOS ONE
Content:
Identifiers:
Authors:
Caroline C. Chisenga , author
Abdallah M. Samy , editor
Samuel Bosomprah , author
Kalo Musukuma , author
Cynthia Mubanga , author
Obvious N. Chilyabanyama , author
Rachel M. Velu , author
Young Chan Kim , author
Arturo Reyes-Sandoval , author
Roma Chilengi , author
Date:
2020-07-01
Journal:
PLOS ONE
Content:
Identifiers:

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