EDCTP Alumni Network

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All Profiles
Call Career Development Fellowship (CDF)
Programme EDCTP2
Start Date 2018-07-01
End Date 2021-06-30
Project Code TMA2016CDF1550
Status Active

Title

Immunogenicity to cholera vaccine within a population at risk in Zambia: mapping the kinetics of immune responses over time

Objectives

• Determine cholera specific antibody titers at baseline (prior vaccination) • Determine seroconversion after 1st and 2nd doses • Asses benefits of a 2nd dose of OCV given after 4 weeks following the 1st dose • Determine if vaccine immune responses wane off at 6, 12, 24, 36, 42 or 48 months post second dose OVC

Host Organisation

Institution Country
Centre for Infectious Disease Research in Zambia (CIDRZ) Zambia

Participants

Name Institution Country
Caroline Cleopatra Chisenga Centre for Infectious Dise

Study Design

This is a pre/post-vaccine study involving a cohort of individuals receiving an oral cholera vaccine provided by the ministry of health (MoH) in response to a cholera outbreak in the Lukanga Swamps. Volunteering eligible individuals were, consented, enrolled and the questionnaire administered.

Sites

Lukanga Swamps-Central Province of Zambia

Students Supervised

Type Name Title University Start Date End Date
MSc Student Harriet Ngombe Ms University of Zambia

Results & Outcomes

In progress

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