Senior Fellowship (SF)
Malaria baseline studies towards characterising and establishing a clinical
trial site at Mutengene, South West Region of Cameroon
The epidemiological study was designed to provide data on baseline
malariometric parameters valuable for future intervention studies aimed
at validating disease control tools.
The specific objectives include conducting a population census of the
study area, determining the malaria prevalence rates
and density in cross sectional surveys, helminth and malaria co-infection
rates and densities, number of episodes per
year in cohort longitudinal studies, vectors transmitting parasites, their
dynamics and inoculation rates, natural immune responses to malaria
parasite exposure and prevalence of some genetic traits that protect
|University of Buea
||University of Buea
Epidemiological studies for clinical trials site development
|Mutengene, Fako Division (Cameroon)
Results & Outcomes
At the end of the project a total of 15,344 individuals were included and
a series of baseline studies were conducted. These included studies on
household mosquito net ownership, prevalence of fever, prevalence of
malaria parasitaemia by season, prevalence of intestinal helminthes by
season, prevalence of anaemia, the prevalence of the sickle cell trait
(HbAS) in the study group and levels of Plasmodium falciparum specific
IgE/IgG2 antibodies in study participants. The project is well integrated
within the EDCTP-funded central African network of excellence,
CANTAM, and also received additional funding from the European
Virtual Institute for Malaria Research (EVIMalaR). Eight members of the
study team received various short term trainings.
|Achidi EA, Apinjoh TO, Anchang-Kimbi JK, Yafi CN, Besingi R, Awah NW, Troye-Blomberg M. Plasmodium falciparum Specific IgE, IgG and Anti-GPI IgG Antibodies in Cameroonian Children with Severe and Uncomplicated Malaria. International Journal of Tropical Disease and Health. 2012 Jun; 2(3): 157-172
|Achidi EA, Apinjoh TO, Anchang-Kimbi JK, Mugri RN, Ngwai AN, Yafi CN. Severe and uncomplicated falciparum malaria in children from three regions and three ethnic groups in Cameroon: prospective study. Malaria Journal 2012 Jun 24;11:215.
|Tchinda GG, Atashili J, Achidi EA, Kamga HL, Njunda AL, Ndumbe PM. Impact of malaria on hematological parameters in people living with HIV/AIDS attending the Laquintinie Hospital in Douala, Cameroon. PLoS One. 2012;7(7):e40553. doi: Project Porftolio Page 378 of 622 10.1371/journal.pone.0040553. Epub 2012 Jul 10.