EDCTP Alumni Network

Fostering excellence and collaboration in the next generation of researchers

Call Career Development Fellowship (CDF)
Programme EDCTP2
Start Date 2021-05-01
End Date 2024-04-30
Project Code TMA2020CDF-3152
Status Active

Title

"Slash and Clear" for ONchocerciasis control and Epilepsy prevention (SCONE)

Objectives

The overall objective of this study is to implement the "Slash and Clear" (S&C) vector control intervention (as a complementary strategy to community-directed treatment with ivermectin) along rivers near onchocerciasis-endemic villages and assess its potential impact on onchocerciasis and epilepsy. Specifically, we seek to: • Map blackfly breeding sites and obtain updated data on onchocerciasis endemicity and ongoing transmission in the Mbam and Sanaga river valleys of Cameroon • Investigate the feasibility and acceptability of S&C in selected Cameroonian villages which are meso/hyperendemic for onchocerciasis • Evaluate the impact of repeated annual S&C on transmission patterns and infection trends of onchocerciasis, as well as on epilepsy incidence in the study villages

Host Organisation

Institution Country
Brain Research Africa Initiative (BRAIN) Cameroon

Study Design

Prospective, community-based, cluster randomized trial with a duration of three years.

Sites

Ntui Health District, Cameroon

Publications

Parasites Vectors. 2022;15(1):444. doi:10.1186/s13071-022-05585-0
Epilepsy Behav. 2023;142:109184. doi:10.1016/j.yebeh.2023.109184

Current Organisation

Brain Research Africa Initiative (BRAIN)

Current Job Title

Research Officer

Students Supervised

Type Name Title University Start Date End Date

Memberships

Role Committee/board Start Date End Date

Education

Institution Degree Year
University of Antwerp, Belgium PhD 2020-09-23
Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Cameroon Doctorate in Medicine (MD) 2015-10-22

Areas Of Specialisation

Neglected Infectious Diseases (NID)

Grants

Publications

Authors:
Alfred Dusabimana , author
Joseph Nelson Siewe Fodjo , author
Michel Mandro Ndahura , author
Bruno P. Mmbando , author
Stephen Raimon Jada , author
Annelies Boven , author
Eric De Smet , author
Tony Ukety , author
Alfred K. Njamnshi , author
Anne Laudisoit , author
Steven Abrams , author
Robert Colebunders , author
Date:
2022-02-23
Journal:
Pathogens
Content:
Authors:
An Hotterbeekx , author
Jolien Perneel , author
Michel Mandro , author
Germain Abhafule , author
Joseph Nelson Siewe Fodjo , author
Alfred Dusabimana , author
Steven Abrams , author
Samir Kumar-Singh , author
Robert Colebunders , author
Date:
2020-06-02
Journal:
Pathogens
Content:
Authors:
Salvatore Metanmo , author
María-Gloria Basáñez , editor
Farid Boumédiène , author
Pierre-Marie Preux , author
Robert Colebunders , author
Joseph N. Siewe Fodjo , author
Eric de Smet , author
Emmanuel Yangatimbi , author
Andrea S. Winkler , author
Pascal Mbelesso , author
Daniel Ajzenberg , author
Date:
2021-06-18
Journal:
PLOS Neglected Tropical Diseases
Content:
Authors:
Janeth Dula , author
Alexandre Mulhanga , author
Armindo Nhanombe , author
Laurentino Cumbi , author
António Júnior , author
Joe Gwatsvaira , author
Joseph Nelson Siewe Fodjo , author
Edlaine Faria de Moura Villela , author
Sérgio Chicumbe , author
Robert Colebunders , author
Date:
2021-07-27
Journal:
Vaccines
Content:
Authors:
Robert Colebunders , author
Joseph Nelson Siewe Fodjo , author
Guido Vanham , author
Rafael Van den Bergh , author
Date:
2020-08-01
Journal:
International Journal of Infectious Diseases
Content:
Authors:
Alfred Dusabimana , author
Dan Bhwana , author
Stephen Raimon , author
Bruno P. Mmbando , author
An Hotterbeekx , author
Floribert Tepage , author
Michel Mandro , author
Joseph N. Siewe Fodjo , author
Steven Abrams , author
Robert Colebunders , author
Date:
2020-07-29
Journal:
Pathogens
Content:
Authors:
António Júnior , author
Janeth Dula , author
Sérgio Mahumane , author
Olivier Koole , author
Sónia Enosse , author
Joseph Nelson Siewe Fodjo , author
Robert Colebunders , author
Date:
2021-01-26
Journal:
International Journal of Environmental Research and Public Health
Content:
Authors:
T. L. Lakwo , author
S. Raimon , author
M. Tionga , author
J. N. Siewe Fodjo , author
P. Alinda , author
W. J. Sebit , author
J. Y. Carter , author
R. Colebunders , author
Date:
2020-04-24
Journal:
Pathogens
Content:
Authors:
Joseph Nelson Siewe Fodjo , author
Melissa Krizia Vieri , author
Leonard Ngarka , author
Wepnyu Y Njamnshi , author
Leonard N Nfor , author
Michel Karngong Mengnjo , author
Adam Hendy , author
Peter A Enyong , author
Dennis Palmer , author
Maria-Gloria Basanez , author
Robert Colebunders , author
Alfred K Njamnshi , author
Date:
2021-09-01
Journal:
BMJ Open
Content:
Authors:
Nhan Phuc Thanh Nguyen , author
Duong Dinh Le , author
Robert Colebunders , author
Joseph Nelson Siewe Fodjo , author
Trung Dinh Tran , author
Thang Van Vo , author
Date:
2021-07-10
Journal:
International Journal of Environmental Research and Public Health
Content:
Authors:
Robert Colebunders , author
Christoph Kaiser , author
Maria-Gloria Basáñez , author
Piero Olliaro , author
Tom Lakwo , author
Joseph Nelson Siewe Fodjo , author
Date:
2022-03-01
Journal:
International Journal of Infectious Diseases
Content:
Authors:
Suzanna Bono , author
Edlaine Faria de Moura Villela , author
Ching Sin Siau , author
Won Sun Chen , author
Supa Pengpid , author
M Tasdik Hasan , author
Philippe Sessou , author
John D. Ditekemena , author
Amodan , author
Mina C. Hosseinipour , author
Housseini Dolo , author
Joseph Nelson Siewe Fodjo , author
Wah Yun Low , author
Robert Colebunders , author
Date:
2021-05-01
Journal:
Vaccines
Content:
Authors:
J.N. Siewe Fodjo , author
F. Tepage , author
R. Colebunders , author
Date:
2019-05-01
Journal:
International Journal of Infectious Diseases
Content:
Authors:
Michel Mandro , author
Delia Goletti , editor
Joseph Nelson Siewe Fodjo , author
Deby Mukendi , author
Alfred Dusabimana , author
Sonia Menon , author
Steven Haesendonckx , author
Richard Lokonda , author
Swabra Nakato , author
Francoise Nyisi , author
Germain Abhafule , author
Deogratias Wonya’Rossi , author
Jean Marie Jakwong , author
Patrick Suykerbuyk , author
Jacques Meganck , author
An Hotterbeekx , author
Robert Colebunders , author
Date:
2020-01-10
Journal:
PLOS Neglected Tropical Diseases
Content:
Authors:
John D. Ditekemena , author
Hypolite M. Mavoko , author
Michael Obimpeh , author
Stijn Van Hees , author
Joseph Nelson Siewe Fodjo , author
Dalau M. Nkamba , author
Antoinette Tshefu , author
Wim Van Damme , author
Jean Jacques Muyembe , author
Robert Colebunders , author
Date:
2021-03-04
Journal:
International Journal of Environmental Research and Public Health
Content:
Authors:
Michel Mandro , author
Joseph Nelson Siewe Fodjo , author
Alfred Dusabimana , author
Deby Mukendi , author
Steven Haesendonckx , author
Richard Lokonda , author
Swabra Nakato , author
Francoise Nyisi , author
Germain Abhafule , author
D Wonya’rossi , author
An Hotterbeekx , author
Steven Abrams , author
Robert Colebunders , author
Date:
2020-03-10
Journal:
Pathogens
Content:
Authors:
John D. Ditekemena , author
Christophe Luhata , author
Hypolite M. Mavoko , author
Joseph Nelson Siewe Fodjo , author
Dalau M. Nkamba , author
Wim Van Damme , author
Shahul H. Ebrahim , author
Christiana Noestlinger , author
Robert Colebunders , author
Date:
2021-05-12
Journal:
International Journal of Environmental Research and Public Health
Content:
Authors:
Joseph Nelson Siewe Fodjo , author
Michel Ndahura Mandro , author
Deby Mukendi , author
Floribert Tepage , author
Sonia Menon , author
Swabra Nakato , author
Nyisi Françoise , author
Germain Abhafule , author
Deogratias Wonya'rossi , author
Aimé Anyolito , author
Richard Lokonda , author
An Hotterbeekx , author
Robert Colebunders , author
Date:
2019-03-13
Journal:
Content:
Authors:
Edlaine Faria de Moura Villela , author
Izadora Rodrigues da Cunha , author
Joseph Nelson Siewe Fodjo , author
Michael Obimpeh , author
Robert Colebunders , author
Stijn Van Hees , author
Date:
2021-06-17
Journal:
International Journal of Environmental Research and Public Health
Content:
Authors:
Mohammed A. M. Ahmed , author
Joseph Nelson Siewe Fodjo , author
Abdi A. Gele , author
Abdiqani A. Farah , author
Shariff Osman , author
Ibraahim Abdullahi Guled , author
Abdiaziz Mohamed Ali , author
Robert Colebunders , author
Date:
2020-09-06
Journal:
Pathogens
Content:
Authors:
Alfred Dusabimana , author
Dan Bhwana , author
Michel Mandro , author
Bruno P. Mmbando , author
Joseph N. Siewe Fodjo , author
Robert Colebunders , author
Date:
2020-10-16
Journal:
Pathogens
Content:
Authors:
Joseph Nelson Siewe Fodjo , author
Leonard Ngarka , author
Wepnyu Y. Njamnshi , author
Leonard N. Nfor , author
Michel K. Mengnjo , author
Edwige L. Mendo , author
Samuel A. Angwafor , author
Jonas Guy Atchou Basseguin , author
Cyrille Nkouonlack , author
Edith N. Njit , author
Nene Ahidjo , author
Eric Samuel Chokote , author
Fidèle Dema , author
Julius Y. Fonsah , author
Godwin Y. Tatah , author
Nancy Palmer , author
Paul F. Seke Etet , author
Dennis Palmer , author
Dickson S. Nsagha , author
Daniel E. Etya’ale , author
Stephen Perrig , author
Roman Sztajzel , author
Jean-Marie Annoni , author
Anne-Cécile Zoung-Kanyi Bissek , author
Rose G. F. Leke , author
Marie-Thérèse Abena Ondoa Obama , author
John N. Nkengasong , author
Robert Colebunders , author
Alfred K. Njamnshi , author
Date:
2021-03-04
Journal:
International Journal of Environmental Research and Public Health
Content:
Authors:
Joseph Nelson Siewe Fodjo , author
Marieke C. J. Dekker , author
Richard Idro , author
Michel Ndahura Mandro , author
Pierre-Marie Preux , author
Alfred K. Njamnshi , author
Robert Colebunders , author
Date:
2019-12-01
Journal:
Infectious Diseases of Poverty
Content:
Authors:
Eric de Smet , author
Salvatore Metanmo , author
Pascal Mbelesso , author
Benoit Kemata , author
Joseph N. Siewe Fodjo , author
Farid Boumédiène , author
Hilda T. Ekwoge , author
Emmanuel Yangatimbi , author
Daniel Ajzenberg , author
Orphee Badibanga , author
Pierre-Marie Preux , author
Robert Colebunders , author
Date:
2020-04-30
Journal:
Pathogens
Content:
Authors:
Date:
2019-06-28
Journal:
International Health
Content:
Abstract During door-to-door surveys in onchocerciasis-endemic regions in Africa, the age-specific ivermectin coverage in 29 722 individuals was assessed. Children 5–6 y of age had significantly lower coverage compared with older participants. Insufficient ivermectin intake among young children could prolong onchocerciasis elimination prospects, as they may serve as human reservoirs of Onchocerca volvulus; moreover, it increases the risk of developing onchocerciasis-associated epilepsy (OAE). The causes of the low ivermectin coverage observed among children 5–6 y of age need to be explored. Integrating ivermectin distribution into chemoprophylaxis strategies for other neglected diseases could increase coverage in a cost-effective manner.
Authors:
An Hotterbeekx , author
Alfred Dusabimana , author
Michel Mandro , author
Germain M Abhafule , author
Wonya’Rossy Deogratias , author
Joseph N. Siewe Fodjo , author
Steven Abrams , author
Robert Colebunders , author
Date:
2020-03-05
Journal:
Pathogens
Content:
Authors:
Michel Mandro , author
Alfred Dusambimana , author
Joseph Nelson Siewe Fodjo , author
Deby Mukendi , author
Stephen Haesendonckx , author
Richard Lokonda , author
Swabra Nakato , author
francoise Nyis , author
Gearge Abhafule , author
D Wonya’ross , author
An Hotterbeekx , author
Steven Abrams , author
Robert Colebunders , author
Date:
2020-01-22
Journal:
Content:
Authors:
Date:
2019-12-01
Journal:
Infectious Diseases of Poverty
Content:
Authors:
Alfred Dusabimana , author
Solomon Tsebeni Wafula , author
Stephen Jada Raimon , author
Joseph Nelson Siewe Fodjo , author
Dan Bhwana , author
Floribert Tepage , author
Gasim Abd-Elfarag , author
An Hotterbeekx , author
Steven Abrams , author
Robert Colebunders , author
Date:
2020-12-31
Journal:
Pathogens
Content:
Authors:
Date:
2019-01-01
Journal:
Global Mental Health
Content:
Background.Until recently, nodding syndrome (NS) was considered as a mysterious disease of unknown etiology. A link between onchocerciasis and epilepsy was suspected for a long time. However, onchocerciasis was not considered as the cause of NS because NS was believed to occur only in onchocerciasis-endemic regions in Uganda, South Sudan, and Tanzania. In October 2015, with funding from the European Research Council, the NSETHIO group launched a trans-disciplinary, multi-country research project to identify the cause of NS and to study the link between onchocerciasis and epilepsy.Methods.We reviewed NSETHIO activities as well as all published papers, and compared project findings with results of previous research on NS.ResultsFindings from the NSETHIO project showed that NS is only one of the clinical manifestations in the wide spectrum of onchocerciasis-associated epilepsy (OAE) that could be prevented by strengthening onchocerciasis elimination programs. NSETHIO demonstrated that OAE is an important neglected public health problem in onchocerciasis-endemic areas with no or a sub-optimally functioning onchocerciasis control strategies.Conclusions.Today there is overwhelming evidence that NS together with the Nakalanga syndrome is clinical presentations of OAE, a condition that could be prevented by strengthening onchocerciasis elimination programs. While research needs to continue to elucidate the pathophysiological mechanisms causing NS, new strategies to accelerate onchocerciasis elimination coupled with community-based surveillance and treatment programs for epilepsy are urgently needed in areas of high Onchocerca volvulus transmission.
Authors:
Date:
2019-11-01
Journal:
International Journal of Infectious Diseases
Content:
Authors:
Nhan Phuc Thanh Nguyen , author
James Curtis West , editor
Tuyen Dinh Hoang , author
Vi Thao Tran , author
Cuc Thi Vu , author
Joseph Nelson Siewe Fodjo , author
Robert Colebunders , author
Michael P. Dunne , author
Thang Van Vo , author
Date:
2020-09-09
Journal:
PLOS ONE
Content:
Authors:
Date:
2019-07-18
Journal:
PLOS Neglected Tropical Diseases
Content:
Authors:
Joseph Nelson Siewe Fodjo , author
Edlaine Faria de Moura Villela , author
Stijn Van Hees , author
Pieter Vanholder , author
Patrick Reyntiens , author
Robert Colebunders , author
Date:
2021-04-27
Journal:
International Journal of Environmental Research and Public Health
Content:
Authors:
Bob O. Amodan , author
Lilian Bulage , author
Elizabeth Katana , author
Alex R. Ario , author
Joseph N. Siewe Fodjo , author
Robert Colebunders , author
Rhoda K. Wanyenze , author
Date:
2020-11-27
Journal:
International Journal of Environmental Research and Public Health
Content:
Authors:
Date:
2019-12-01
Journal:
Infectious Diseases of Poverty
Content:
Authors:
John Dinanga Ditekemena , author
Dalau Mukadi Nkamba , author
Hypolite Mavoko Muhindo , author
Joseph Nelson Fodjo Siewe , author
Christophe Luhata , author
Rafael Van den Bergh , author
Antoinette Tshefu Kitoto , author
Wim Van Damme , author
Jean Jacques Muyembe , author
Robert Colebunders , author
Date:
2021-01-01
Journal:
BMJ Open
Content:
Authors:
Date:
2019-12-01
Journal:
Infectious Diseases of Poverty
Content:
Authors:
Date:
2018-12-01
Journal:
Infectious Diseases of Poverty
Content:
Authors:
Mohammed A.M. Ahmed , author
Robert Colebunders , author
Joseph Nelson Siewe Fodjo , author
Date:
2020-06-01
Journal:
International Journal of Infectious Diseases
Content:
Authors:
Stephen Raimon , author
LAKWO THOMSON LURONI , author
Wilson John Sebit , author
Joseph Nelson Siewe Fodjo , author
Peter Alinda , author
Jane Carter , author
Rory J. Post , author
Robert Colebunders , author
Date:
2021-10-01
Journal:
Pathogens
Content:
Authors:
Joseph Nelson Siewe Fodjo , author
Michel Mandro , author
Deogratias Wonya'rossi , author
Yasemine Inaç , author
Francoise Ngave , author
Richard Lokonda , author
Aimé Anyolito , author
Frederik Verelst , author
Robert Colebunders , author
Date:
2019-03-01
Journal:
EClinicalMedicine
Content:
Authors:
John D. Ditekemena , author
Dalau M. Nkamba , author
Armand Mutwadi , author
Hypolite M. Mavoko , author
Joseph Nelson Siewe Fodjo , author
Christophe Luhata , author
Michael Obimpeh , author
Stijn Van Hees , author
Jean B. Nachega , author
Robert Colebunders , author
Date:
2021-02-14
Journal:
Vaccines
Content:
Authors:
Alexandre Morin , author
Maxime Guillaume , author
Leonard Ngarka , author
Godwin Y. Tatah , author
Joseph Nelson Siewe Fodjo , author
Guillaume Wyart , author
Ghislain Nokam , author
Thierry Tchoumi , author
Mary Bello Nkinin , author
Wepnyu Y. Njamnshi , author
Eric‐Samuel Chokote , author
Michel Boussinesq , author
Robert Colebunders , author
Cédric B. Chesnais , author
Gilles Gargala , author
Dominique Parain , author
Alfred K. Njamnshi , author
Date:
2021-09-03
Journal:
Epilepsia Open
Content:
Authors:
Robert Colebunders , author
Gasim Abd-Elfarag , author
Jane Y. Carter , author
Peter Claver Olore , author
Kai Puok , author
Sonia Menon , author
Joseph Nelson Fodjo Siewe , author
Samit Bhattacharyya , author
Morrish Ojok , author
Richard Lako , author
Makoy Yibi Logora , author
Date:
2018-11-01
Journal:
Seizure
Content:
Authors:
Date:
2019-01-01
Journal:
Epilepsy & Behavior
Content:
Authors:
Mohammed A. M. Ahmed , author
Robert Colebunders , author
Abdi A. Gele , author
Abdiqani A. Farah , author
Shariff Osman , author
Ibraahim Abdullahi Guled , author
Aweis Ahmed Moalim Abdullahi , author
Ahmed Mohamud Hussein , author
Abdiaziz Mohamed Ali , author
Joseph Nelson Siewe Fodjo , author
Date:
2021-05-21
Journal:
Vaccines
Content:
Authors:
Date:
2019-12-01
Journal:
The Lancet
Content:
Authors:
Suzanna Bono , author
Ching Sin Siau , author
Won Sun Chen , author
Wah Yun Low , author
Edlaine Faria de Moura Villela , author
Supa Pengpid , author
M Tasdik Hasan , author
Philippe Sessou , author
John D. Ditekemena , author
Amodan , author
Mina C. Hosseinipour , author
Housseini Dolo , author
Joseph Nelson Siewe Fodjo , author
Robert Colebunders , author
Date:
2021-12-01
Journal:
Vaccines
Content:
Authors:
Melissa Krizia Vieri , author
Michel Mandro , author
Chiara Simona Cardellino , author
Pierantonio Orza , author
Niccolò Ronzoni , author
Joseph Nelson Siewe Fodjo , author
An Hotterbeekx , author
Robert Colebunders , author
Date:
2021-03-18
Journal:
Pathogens
Content:
Authors:
Tuyen Dinh Hoang , author
Robert Colebunders , author
Joseph Nelson Siewe Fodjo , author
Nhan Phuc Thanh Nguyen , author
Trung Dinh Tran , author
Thang Van Vo , author
Date:
2021-04-29
Journal:
International Journal of Environmental Research and Public Health
Content:

Projects

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