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All Profiles
Call Senior Fellowship (SF)
Programme EDCTP1
Start Date 2011-04-11
End Date 2013-04-10
Project Code TA.2010.40200.032
Status Completed

Title

Intermittent preventive treatment in children combined with malaria home management in an area with persisting high malaria prevalence in Senegal

Objectives

To determine whether seasonal IPTc with sulfadoxine-pyrimethamine plus amodiaquine provide added benefit in populations with access to prompt effective treatment through home–based management; whether IPTc has previously been shown effective when give for three months in areas with a short transmission season and whether seasonal IPTc is safe and acceptable when given for a longer period in areas with a longer transmission season. To also show the cost-effectiveness of adding seasonal IPTc to home management of malaria (HMM)

Host Organisation

Institution Country
University Cheikh Anta Diop of Dakar Senegal
University of Thies Senegal

Participants

Name Institution Country
Jean louis Abdourahim Ndiaye University Cheikh Anta DIOP de Dakar (UCAD) Senegal
Paul Milligan London School of Hygiene and Tropical Medicina (LSHTM) United Kingdom
Youssoupha Ndiaye Ministere de la sante et de la prevetion medicale, Senegal Senegal
Pape Moussa Thior Ministere de la sante et de la prevention medicale Senegal

Study Design

Phase III: Cluster randomised trial

Sites

Saraya, south Senegal

Phd Study

Title University Start Date End Date
Clinical and biological response and genetic diversity of Plasmodium falciparum during uncomplicated malaria episodes treated with ACTs in rural areas in Senegal UCAD 2008-01-12 2011-07-12

Students Supervised

Type Name Title University Start Date End Date
MSc in Parasitology Mamadou Sarifou Ba Dr UCAD 2011 2013

Results & Outcomes

Twenty four community health workers and malaria volunteers were trained by the Department of Parasitology to do thick and thin blood smear to confirm all malaria cases in the 24 villages involved in the project.

Publications

Ndiaye JLA, Ndiaye Y, Ba MS, Faye B, Ndiaye M, Seck A, et al. (2019) Seasonal malaria chemoprevention combined with community case management of malaria in children under 10 years of age, over 5 months, in south-east Senegal: A cluster-randomised trial. PLoS Med 16(3): e1002762. https://doi.org/10.1371/journal.pmed.1002762

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