EDCTP Alumni Network

Fostering excellence and collaboration in the next generation of researchers

Call Career Development Fellowship (CDF)
Programme EDCTP2
Start Date 2021-11-01
End Date 2024-10-31
Project Code TMA2020CDF-3159
Status Active

Title

Pathogen detection in HIV-infected children and adolescents with non-malarial febrile illnesses using metagenomic next-generation sequencing approach in Uganda

Host Organisation

Institution Country

Current Organisation

INFECTIOUS DISEASES INSTITUTE

Current Job Title

Scientist

Awards

2021 Training & Mobility Action (TMA)

Students Supervised

Type Name Title University Start Date End Date
2 Gerald Mboowa Makerere University 2021 2023

Memberships

Role Committee/board Start Date End Date
Associate Editor BMC Infectious Diseases 2020
Academic Editor Global Health, Epidemiology and Genomics 2021

Education

Institution Degree Year
Makerere University, Uganda PhD 2020-01-14

Areas Of Specialisation

Tuberculosis (TB) Lower Respiratory Tract Infections (LRTIs) Diarrhoeal Diseases (DDs)

Grants

Publications

Authors:
Gerald Mboowa , Mboowa G. Reviewing the journey to the clinical application of bacteriophages to treat multi-drug-resistant bacteria. BMC Infect Dis. 2023 Oct 3;23(1):654. doi: 10.1186/s12879-023-08621-1. PMID: 37789281; PMCID: PMC10548642.
Date:
2023-10-05
Journal:
BMC Infectious Diseases
Content:

Antimicrobial resistance (AMR) was a leading cause of death globally in 2019. Sadly, COVID-19 has exacerbated AMR, nonetheless, the process of developing new antibiotics remains very challenging. This urgently requires the adoption of alternative approaches to treat multi-drug-resistant bacterial infections. This editorial introduces the ‘Bacteriophages against multi-drug resistant bacteria’ collection launched at BMC Infectious Diseases which highlights progress towards using bacteriophages to tackle AMR

Authors:
Date:
2023-04-21
Journal:
Immunogenetics
Content:

In modern medicine, vaccination is one of the most effective public health strategies to prevent infectious diseases. Indisput- ably, vaccines have saved millions of lives by reducing the burden of many serious infections such as polio, tuberculosis, measles, pneumonia, and tetanus. Despite the recent recommendation by the World Health Organization (WHO) to roll out RTS,S/AS01, this malaria vaccine still faces major challenges of variability in its efficacy partly due to high genetic variation in humans and malaria parasites. Immune responses to malaria vary between individuals and populations. Human genetic variation in immune system genes is the probable cause for this heterogeneity. In this review, we will focus on human genetic factors that determine variable responses to vaccination and how variation in immune system genes affect the immunogenic- ity and efficacy of the RTS,S/AS01 vaccine.

Projects

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