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Call Career Development Fellowship (CDF)
Programme EDCTP2
Start Date 2019-11-01
End Date 2022-10-31
Project Code TMA2018CDF-2351
Status Active


Evaluation of alternative bacteriological measures of response to therapy during the initial 16-weeks of MDR-TB treatment


During the first 16 weeks of MDR-TB treatment I will: 1) To examine the correlations of FDA smear microscopy, PMA-Xpert Ct value &16s rRNA (MBLA) with MGIT-TTP as a reference standard. 2) To evaluate the ability of FDA smear microscopy, PMA-Xpert Ct value, MBLA in predicting 16-weeks MGIT culture conversion (outcome). 3) To evaluate the influence of patient clinical characteristics, baseline resistance profiles, adherence and HIV-status to the performance of the alternative measures of response

Host Organisation

Institution Country
Makerere University Uganda


Name Institution Country
Dr. Wilber Sabiiti University Of St. Andrews United Kingdom

Study Design

Prospective observational study


Mulago National Referral Hospital, Tuberculosis Treatment Unit, Ward 5 and 6

Students Supervised

Type Name Title University Start Date End Date
Masters Serestine Mujumbi MSc. Immunology and Clinical Microbiology Makerere University 2021 2022
PhD Emmanuel Musisi PhD Novel Molecular diagnosis of TB University of St. Andrews 2019 2021

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