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All Profiles

Mr Salou Diallo

Call EDCTP-AREF Preparatory Fellowships (PF)
Programme EDCTP2
Start Date 2021-08-01
End Date 2022-01-31
Project Code TMA2019PF-2739
Status Active

Title

Apply Genomics and Bioinformatics in Buruli Ulcer (FM-DIALLO)

Host Organisation

Institution Country
Institut de Recherche en Science de la Santé (IRSS)/ Clinical Research Unit of Nanoro (CRUN) Burkina Faso

Grants

Folate nutritional status and malaria risk in mostly adolescent pregnant and non-pregnant women living in a high malaria endemic area of Burkina Faso
Grant Code:
TMA.2019.PF.2739-FA
Source of funding:
European and Developing Countries Clinical Trials Partnership (EDCTP)
Amount:
70000
Role:
Principal Investigator
Start Date:
2021-01-01
End Date:
2022-01-01

Publications

Projects

Folate nutritional status and malaria risk in mostly adolescent pregnant and non-pregnant women livi
Fellow:
Salou Diallo
Collaborators:
Name Country Institution
Diallo Salou Burkina Faso Clinical Research Unit of Nanoro
Objectives:
• Non pregnant women - Describe the cross-sectional folate and vitamin B12 nutritional concentrations at baseline (235 ENR samples); Determine the longitudinal change of folate concentration between baseline (235 ENR samples) and end assessment (235 FIN samples). - Assess the folate status by age in adolescents’ women (235 ENR samples). - Describe folate and vitamin B12 nutritional status (FIN samples) in relation to anemia. - Assess changes in homocysteine concentration between baseline (235 ENR samples) and end assessment (235 FIN samples) following folic acid and/or iron supplementation. • Pregnant women - Describe folate and vitamin B12 nutritional status in pregnant women (315 ANC1 samples), also in relation to anemia. - In a sub-sample (57) seen at both FIN and ANC1 assess longitudinal change in folate concentration following folic acid supplementation - In the single participant (participant number 1710) delivering a baby with a neural tube defect, determine folate/B12/homocysteine concentration at ENR and ANC1. Malaria objectives - In non-pregnant women cohort assess malaria risk at end assessment (FIN: 257 samples) in relation to their folate/B12 status at enrolment (ENR:257). - In a cross-sectional sample of the non-pregnant cohort at FIN (235) assess malaria risk in relation to their folate/B12 status. - In the pregnant sample at ANC1, assess malaria risk in relation to their folate/B12 at ANC1.
Sites:
Nanoro, Burkina Faso
Study Design:
We propose to undertake an extended secondary analysis of nutritional and inflammatory biomarkers using reserve sera obtained in a completed periconceptional controlled trial of iron and folic acid supplementation in Burkina Faso, in order to determine the framework for a subsequent
Subjects:
Human
Start Date:
2021-09-01
End Date:
2022-05-01

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