EDCTP Alumni Network

Fostering excellence and collaboration in the next generation of researchers

Call EDCTP Clinical Research & Development Fellowship (R&D F)
Programme EDCTP2
Start Date 2020-02-01
End Date 2023-11-01
Project Code TMA2018IF-2484
Status Active

Title

EDCTP Clinical Research and Product Development Fellowship TMA2018IF-SOMA

Host Organisation

Institution Country
WWARN/IDDO, University of Oxford United Kingdom

Current Organisation

Institut National de Santé Publique / Centre MURAZ

Current Job Title

Biologist

Memberships

Role Committee/board Start Date End Date
Reporter Institutional Ethic Committee of INSP 2021 2024

Education

Institution Degree Year
Universite Joseph KI ZERBO, Burkina Faso PhD 2020-10-08
Universite Joseph KI ZERBO, Burkina Faso MSc 2011-07-14
Universite Joseph KI ZERBO, Burkina Faso Licence 2007-09-30

Areas Of Specialisation

Malaria

Publications

Authors:
Date:
2017-02-07
Journal:
African Journal of Pharmacy and Pharmacology
Content:
Identifiers:
Authors:
Date:
2018-01-01
Journal:
Evidence-Based Complementary and Alternative Medicine
Content:
Up to now, the control of malaria remains a challenge. The World Health Organization (WHO) recommends the use of artemisinin-based combination therapies (ACTs) for uncomplicated malaria treatment. Despite this guideline, many people in Burkina Faso use herbal medicine as primary treatment against malaria. The aim of this study was to assess the in vivo activity of Guiera senegalensis J. F. Gmel and Bauhinia rufescens Lam. leaves extracts against Plasmodium berghei ANKA. A four-day treatment of leaves decoction of each plant was administrated orally to 7 groups of six NMRI (Naval Medical Research Institute) mice infected with Plasmodium berghei ANKA strain. The control group received distilled water as treatment while the treated groups each received daily 100, 250, and 500 mg extract/kg body weight. Thin blood smears were performed on day five and the percentage of reduction of parasitaemia was determined compared to the control. The percentages of reduction of the parasitaemia at the doses of 100, 250, and 500 mg extract/kg body weight were, respectively, 57.5%, 35.9%, and 44.9% for Guiera senegalensis and 50.6%, 22.2%, and 25.7% for Bauhinia rufescens. Our findings on antiplasmodial activity of these two plants justify the traditional use by local populations against malaria. Thus, the isolation of the active compounds from these two plants is suggested for possible antimalarial candidate drugs.
Identifiers:
DOI: 10.1155/2018/6859632
Part of ISSN: 1741-427X
Part of ISSN: 1741-4288
Authors:
Date:
2019-01-01
Journal:
SCHOLARENA www.scholarena SAJ Pharmacy and Pharmacology
Content:
Identifiers:

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