Dr Aboubakar Soma
| Call | EDCTP Clinical Research & Development Fellowship (R&D F) |
| Programme | EDCTP2 |
| Start Date | 2020-02-01 |
| End Date | 2022-10-31 |
| Project Code | TMA2018IF-2484 |
| Status | Active |
Title
Infectious Diseases Data Observatory (IDDO), University of Oxford, United Kingdom
Objectives
Training Plan Goal: To acquire advanced knowledge and skills in clinical trials design, data analysis and data sharing, operations for implementation of research action and development in Africa. Objectives • Gain skills in clinical trial design • Gain skills in statistics, sample size calculation and data analysis • Gain skills in protocol development and systematics reviews • Gain skills in online English course and have a direct contact with community of researchers • Enhance skills in clinical trial toolkits on antimalarial drug • Acquire skills in other relevant training opportunities
Host Organisation
| Institution | Country |
|---|---|
| University of Oxford | United Kingdom |
Study Design
During the fellowship in the host organization, I will carry out following activities: • English courses • Training on clinical trials design at IDDO • Training on statistics, sample size calculation and data analysis at IDDO • Training on protocol development and systematics reviews at IDDO • Training on clinical trial toolkits on antimalarial drug at IDDO • Training on other relevant training opportunities at IDDO(e.g: Database design, introduction to R and Stata, Geospatial analysis using ArcGIS etc) • Training modules on good practice in data management, ethics data and anti-malaria toolkits of IDDO
Current Organisation
Infectious Diseases Data Observatory, University of Oxford
Current Job Title
EDCTP-Fellow/ Visiting Researcher
Awards
| 2018 | TMA2018IF-2484 |
Students Supervised
| Type | Name | Title | University | Start Date | End Date |
|---|
Memberships
| Role | Committee/board | Start Date | End Date |
|---|---|---|---|
| Reporter | Institutional Ethic Committee of INSP | 2021 | 2024 |
Education
| Institution | Degree | Year |
|---|---|---|
| Universite Joseph KI ZERBO, Burkina Faso | PhD | 2020-10-08 |
| Universite Joseph KI ZERBO, Burkina Faso | MSc | 2011-07-14 |
| Universite Joseph KI ZERBO, Burkina Faso | Licence | 2007-09-30 |
Areas Of Specialisation
Malaria
Grants
Publications
Authors:
Date:
2018-01-01
Journal:
Evidence-Based Complementary and Alternative Medicine
Content:
Authors:
SIRIMA Sodiomon Bienvenu
, Groupe de Recherche Action en Santé (GRAS), 06 BP 10248 Ouagadougou 06 Burkina Faso.
Date:
2021-12-31
Journal:
Academic Journal: African Journal of Pharmacy and Pharmacology
Content:
In the crude extracts of the bark and leaves of Sclerocarya birrea, have been characterized sterols,
triterpenes, saponosides, tannins, anthocyanosides, coumarins, reducing compounds, alkaloids and
carotenoids. Tests were carried out in vitro with extracts from each part of the plant to assess their
efficacy against strains of Plasmodium falciparum sensitive to chloroquine K1 and that resistant to
chloroquine 3D7. The crude alkaloidal extracts of the bark gave IC50 = 2.54 μg / ml with the strain 3D7
and an IC50 = 4.09 μg / ml with the strain K1. On the other hand, the extracts with CH2Cl2 showed an
IC50 = 36.59 and 37.78 μg / ml respectively with the 3D7 and K1 strains. Those with CH3OH gave IC50 all
greater than 50 μg/ml with both strains. The CH3OH / H2O extracts gave IC50 = 21.48 μg / ml with the K1
strain and greater than 50 μg / ml with 3D7. As for the H2O extracts, the IC50 were = 11.43 μg / ml with
the K1 strain and also greater than 50 μg / ml with the 3D7. The alkaloid extracts of leaf gave an IC50 =
9.68 μg / ml with 3D7 and = 3.56 μg / ml with strain K1. With CH2Cl2, and IC50 = 6.62 μg / ml was obtained
with 3D7 and 4.05 μg / ml with strain K1. The CH3OH extracts gave an IC50 = 21.12 μg / ml with the 3D7
strain and 21.06 μg / ml with the KI strain. The CH3OH / H2O extracts gave with strain 3D7 and IC50 of
more than 50 and 32.73 μg / ml with K1. The aqueous extracts gave IC50 greater than 50 μg / ml for 3D7
and 25.17 μg / ml with the K1 strain.