EDCTP Alumni Network

Fostering excellence and collaboration in the next generation of researchers

All Profiles
Call Career Development Fellowship (CDF)
Programme EDCTP2
Start Date 2018-08-01
End Date 2021-01-31
Project Code TMA2016CDF1555
Status Active

Title

Single low-dose primaquine efficacy and safety for treatment of uncomplicated Plasmodium falciparum malaria based on cytochrome P450 2D6 activity in Bagamoyo district, Tanzania.

Host Organisation

Institution Country
Tropical Pesticides Research Institute (TPRI) Tanzania, United Republic of

Sites

Yombo Primary health facility, Bagamoyo district.

Phd Study

Title University Start Date End Date
Monitoring the efficacy and safety of artemether-lumefantrine alone or plus a single low-dose primaquine for the management of malaria in Bagamoyo district, Tanzania. Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania. 2012-04-01 2016-12-15

Students Supervised

Type Name Title University Start Date End Date
MSc Dominic Msolo Efficacy of single low-dose of primaquine for treatment of uncomplicated Plasmodium falciparum malaria in Tanzania. University of Dar es Salaam, Tanzania 2018 2020

Publications

Mwaiswelo, R.O., Mawala, W., Iversen, P.O. et al. Sickle cell disease and malaria: decreased exposure and asplenia can modulate the risk from Plasmodium falciparum. Malar J 19, 165 (2020). https://doi.org/10.1186/s12936-020-03212-w
Mwaiswelo, R., Ngasala, B., Jovel, I. et al. Adding a single low-dose of primaquine (0.25 mg/kg) to artemether-lumefantrine did not compromise treatment outcome of uncomplicated Plasmodium falciparum malaria in Tanzania: a randomized, single-blinded clinical trial. Malar J 15, 435 (2016). https://doi.org/10.1186/s12936-016-1430-3
Mwaiswelo, R., Ngasala, B.E., Jovel, I. et al. Safety of a single low-dose of primaquine in addition to standard artemether-lumefantrine regimen for treatment of acute uncomplicated Plasmodium falciparum malaria in Tanzania. Malar J 15, 316 (2016). https://doi.org/10.1186/s12936-016-1341-3

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