EDCTP Alumni Network

Fostering excellence and collaboration in the next generation of researchers

Call EDCTP Clinical Research & Development Fellowship (R&D F)
Programme EDCTP2
Start Date 2017-05-01
End Date 2019-01-28
Project Code TMA2015-1167
Status Active

Title

Julius Clinical, Zeist, Netherlands

Objectives

The aim of the placement is to learn and understand the operation of a scientific clinical research organization which will assist the fellow in preparing and conducting future clinical trials and train junior researchers at the home organization.

Host Organisation

Institution Country
Julius Clinical, Zeist Netherlands
TB & HIV Investigative Network (THINK)  South Africa

Study Design

12 Month training at Julius Clinical followed by a 6 months reintegration project at the home institution, THINK.

Current Organisation

THINK: TB and HIV Investigative Network

Current Job Title

Principal Investigator

Awards

2018 University of the Free State Chancellor’s Distinguished Alumni Awards: Cum Laude award

Education

Institution Degree Year
University of the Free State, South Africa MBChB 2008-12-31
University of Stellenbosch, South Africa MPhil 2017-08-12

Areas Of Specialisation

Tuberculosis (TB)

Publications

Authors:
G. Hoddinott , Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine, Stellenbosch University, Cape Town
S. Staples , THINK: TB and HIV Investigative Network, Durban, South Africa
R. Brown , Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine, Stellenbosch University, Cape Town
M. Simwinga , Zambia AIDS Related Tuberculosis (ZAMBART) School of Medicine, Lusaka, Zambia
C. Mubekapi-Musadaidzwa , Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine, Stellenbosch University, Cape Town
A. C. Hesseling , Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine, Stellenbosch University, Cape Town
G. Hendricks , Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine, Stellenbosch University, Cape Town
P. De Koker , Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine, Stellenbosch University, Cape Town
L. McKenna , Treatment Action Group, New York, New York, USA
Date:
2018-09-07
Journal:
International Journal of Tuberculosis and Lung Disease: Pediatric Landscape Supplement
Content:

The paediatric tuberculosis (TB) prevention and treatment landscape is moving into a new and exciting era,with knowledge from clinical trials offering real benefit
to children. Community engagement is key to optimising the success of these trials. However, the clinical profile, epidemiology and social perceptions for paediatric multidrug-resistant TB (MDR-TB) complicate the operationalisation of this community engagement.We reflect on a diversity of recent experiences attempting to
implement this type of research and the community engagement around it. We describe four recommendations and argue that these should guide the implementation of the community engagement agenda in the new landscape of paediatric MDR-TB clinical trials. Specifically, we argue for 1) dynamic, long-term continuity in
community engagement platforms; 2) tiers of TB and research literacy; 3) multiple separate and joint platforms for holding ‘stakes’; and 4) addressing the social/
structural implications of family participation. We conclude that community-level stakeholders, such as health workers, parents and children, are willing to collaborate in paediatric MDR-TB clinical trials. Using these recommendations, there is considerable opportunity for effective community engagement in this new era of paediatric MDR-TB research.

Identifiers:

Send a Message