Mrs Azizath Moussiliou
| Call | Career Development Fellowship (CDF) |
| Programme | EDCTP2 |
| Start Date | 2021-01-01 |
| End Date | 2023-12-31 |
| Project Code | TMA2019CDF-2774 |
| Status | Active |
Title
Impact of seasonal malaria chemoprevention on the acquisition and maintenance of immunity against malaria among children in northern Benin (ISAMIMA)
Host Organisation
| Institution | Country |
|---|---|
| Université de Parakou | Benin |
Current Organisation
University of Parakou
Current Job Title
Associate Professor
Students Supervised
| Type | Name | Title | University | Start Date | End Date |
|---|---|---|---|---|---|
| 1 | Ooumarou Elija | 7th year medicine | University of Parakou | 2016 | 2023 |
Memberships
| Role | Committee/board | Start Date | End Date |
|---|
Education
| Institution | Degree | Year |
|---|---|---|
| University Pierre Marie Curi, France | PhD | 2015-12-15 |
Areas Of Specialisation
Malaria
Grants
Publications
Projects
Fellow:
Azizath Moussiliou
Collaborators:
| Name | Country | Institution |
|---|---|---|
| Ahouansou Charles | Benin | University of Parakou |
Objectives:
• Determine the impact of treatment on the acquisition of anti-malarial antibodies in children before, during and after the intervention
• Determine the impact of treatment on functionality of anti-malarial antibodies in children before, during and after the intervention
• Determine the prevalence of malarial infection in children under five years of age living in northern Benin before, during and after seasonal malaria chemoprevention
Sites:
Children will be enrolled in household
Study Design:
This is a cross-sectional study on children aged 6 to 59 months with/without SMC in two villages in northern Benin. Sociodemographic and clinical data as well as repeated blood samples will be collected from 400 children (before, during and after treatment). Samples will be analyzed using a Luminex assay to investigate antibody responses to MSP, AMA1 and PfEMP1. The functional activity of antibodies will be assessed using receptor binding assay. RTPCR will be used to detect the prevalence of malaria at this period and the repertoire of var gene transcripts of parasites infecting children
Subjects:
Children at Cobly and Tchaourou
Outcomes:
The study will determine the impact of SMC on the development of children’s anti-malarial immunity. It will also identify parasite variants capable of infecting children following treatment. The information collected will help in surveillance efforts of SMC.
Linked Grant:
EDCTP Senior Fellowship grant
Start Date:
2021-06-13
End Date:
2022-04-11