Call | Career Development Fellowship (CDF) |
Programme | EDCTP2 |
Start Date | 2017-04-01 |
End Date | 2020-03-01 |
Project Code | TMA2015CDF976 |
Status | Active |
Cluster randomized community-based trial of annual versus biannual single-dose Ivermectin plus Albendazole against Wuchereria bancrofti infection in human and mosquito populations
• To quantify the impact of twice yearly versus yearly community treatment (treatment strategies and • delivery systems) in reducing parasitological and entomological LF transmission indices in hotspot areas • Assess the impact of the treatment on other helminth infections • To evaluate the costs and cost-effectiveness of twice yearly treatment in reducing disease transmission. • To assess the extent to which the twice-yearly treatment is acceptable to the community and feasible, given the health system capacity, and can be easily scaled-up elsewhere.
Institution | Country |
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Noguchi Memorial Institute for Medical Research, University of Ghana | Ghana |
Phase 4, cluster randomised community based, open label trial
Type | Name | Title | University | Start Date | End Date |
---|---|---|---|---|---|
MPhil | Frances McCarthy | Evaluation of three diagnostic tests for monitoring of lymphatic filariasis elimination in Ahanta West, Ellembelle and Nzema East districts, Western Region, Ghana | University of Ghana | 2017 | 2018 |
Ahorlu CS, Koka E, Adu-Amankwah S, Otchere J, de Souza DK. Community perspectives on persistent transmission of lymphatic filariasis in three hotspot districts in Ghana after 15 rounds of mass drug administration: a qualitative assessment. BMC Public Health 18:238. https://doi.org/10.1186/s12889-018-5157-7 |
de Souza DK, Ahorlu CS, Adu-Amankwah S, Otchere J, Mensah SK, Larbi IA, Mensah GE, Biritwum, Boakye DA. Community-based trial of annual versus biannual single-dose Ivermectin plus Albendazole against Wuchereria bancrofti infection in human and mosquito populations: study protocol for a cluster randomized controlled trial. Trials 18: 448. DOI: 10.1186/s13063-017-2196-9 |
de Souza DK, Gass K, Otchere J, Htet YM, Asiedu O, Marfo B, Biritwum N-K, Boakye DA, Ahorlu CS (2020). Review of MDA registers for Lymphatic Filariasis: Findings, and potential uses in addressing the endgame elimination challenges. PLoS Negl Trop Dis 14(5): e0008306. https://doi.org/10.1371/journal.pntd.0008306 |
de Souza DK, Otchere J, Ahorlu CS, Adu-Amankwah S, Larbi IA, Dumashie E, McCarthy FA, King SA, Otoo S, Osabutey D, Osei JHN, Sedzro KM, Asiedu O, Dadzie SK, Ayi I, Marfo B, Biritwum N-K, Boakye DA (2018). Low Microfilaremia Levels in Three Districts in Coastal Ghana with at Least 16 Years of Mass Drug Administration and Persistent Transmission of Lymphatic Filariasis. Trop Med Infect Dis. 3:105. https://doi.org/10.3390/tropicalmed3040105 |
Agbozo EY, Dumashie E, Boakye DA, de Souza DK (2018). Effects of lyophilization and storage temperature on Wuchereria bancrofti antigen sensitivity and stability. BMC Research Notes 11: 454. https://doi.org/10.1186/s13104-018-3586-0 |
Noguchi Memorial Institute for Medical Research, University of Ghana
Associate Professor of Parasitiology
Type | Name | Title | University | Start Date | End Date |
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Role | Committee/board | Start Date | End Date |
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Institution | Degree | Year |
---|---|---|
Kwame Nkrumah University of Science and Technology, Ghana | PhD (Biological Sciences - Theoretical and Applied Biology) | |
University of Ghana, Ghana | BSc Zoology |
Neglected Infectious Diseases (NID)