Call | Senior Fellowship (SF) |
Programme | EDCTP2 |
Start Date | 2020-01-01 |
End Date | 2024-12-31 |
Project Code | TMA2018SF-2465 |
Status | Active |
Management of Lower Respiratory Tract Infections in Sub-Saharan Africa, a Pragmatic Approach (LoRTISA study)
Institution | Country |
---|---|
Infectious Diseases Institute Limited (IDI) | Uganda |
Call | Senior Fellowship (SF) |
Programme | EDCTP1 |
Start Date | 2011-04-11 |
End Date | 2014-04-10 |
Project Code | TA.2010.40200.0019 |
Status | Completed |
Short- and long-term clinical and immunological outcomes of patients with HIV/TB coinfections on ART
To study short-term effects of TB and ART treatment (the incidence, predictors and clinical characteristics of TB-IRIS, side effects of the therapy, causes of early mortality) and long term effects of ART after completing TB treatment (clinical events such as infections, late-onset IRIS, adverse effects of therapy or immunological and virological events such as changes in CD4 counts, CD4 %; viral load, viral resistance). Also to study possible factors influencing these outcomes such as adherence and factors affecting them, TB relapse and mycobacteriological factors, immunological defects and social factors that are associated with a recurrent TB episode and causes of mortality
Institution | Country |
---|---|
Makerere University | Uganda |
Name | Institution | Country |
---|---|---|
Robert Colebunders | University of Antwerp | Belgium |
Yukari Manabe | Makerere University | Uganda |
A cohort study to compare the effectiveness of early versus delayed antiretroviral therapy on prevention of mortality HIV-TB co-infected patients in a programmatic setting
The HIV-TB Clinic of the Infectious Disease Institute, Kampala, Uganda |
Title | University | Start Date | End Date |
---|---|---|---|
The Challenges of TB-HIV in Resource-limited settings | University of Antwerp, Belgium | 2006-08-25 | 2012-01-12 |
Type | Name | Title | University | Start Date | End Date |
---|---|---|---|---|---|
Masters of Medicine | Dr. Christian Roy Thomas | Dr | Makerere University | 2013 | 2014 |
Targeted recruitment: 189 out of 280 patients were enrolled for the study. Capacity Building: 1) Dr Jabo Christian who enrolled for a Masters of Medicine in Radiology at Makerere University successfully defended his thesis in May 2014. 2) Ms Justine Nakiwala, the PhD student at the Institute of Tropical Medicine, Antwerp who was studying the role of neutrophils in the pathogenesis of TB-IRIS completed the initial stage of her data collection at this site and continued with her PhD work in South Africa.
Worodria W, Ssempijja V, Hanrahan C, Ssegonja R, Muhofwa A, Mazapkwe D, Mayanja-Kizza H, Reynolds SJ, Colebunders R, Manabe YC. Opportunistic diseases diminish the clinical benefit of immediate antiretroviral therapy in HIV-tuberculosis co-infected adults with low CD4+ cell counts. AIDS. 2018 Sep 24;32(15):2141-2149. doi: 10.1097/QAD.0000000000001941. PMID: 30005014 |
Nakiwala JK, Walker NF, Diedrich CR, Worodria W, Meintjes G, Wilkinson RJ, Mayanja-Kizza H, Colebunders R, Kestens L, Wilkinson KA, Lowe DM. Neutrophil activation and enhanced release of granule products in HIV-TB immune reconstitution inflammatory syndrome. J Acquir Immune Defic Syndr. 2018 Feb 1;77(2):221-229. doi: 10.1097/QAI.0000000000001582. |
Mulago Hospital, Kampala, Uganda
Senior Consultant (Internal Medicine) & Head, Division of Respiratory Medicine
2014 | Common Wealth Scholarship for an MSc in Epidemiology and Biostatistics (LSTMH) |
2015 | Post Doctoral Fellowship on TB-HIV at the Infectious Disease Institute, Kampala and Johns Hopkins University |
Type | Name | Title | University | Start Date | End Date |
---|---|---|---|---|---|
Masters | John Lusiba Kafuluma | Dr | Makerere University | 2012 | 2013 |
Masters | Jabo Christian Roy Thomas | Dr | Makerere University | 2013 | 2014 |
Masters | : Acen Lilian Ester | Ms | Makerere University | 2013 | 2014 |
Masters | Louisa Namata | Dr | Makerere University | 2013 | 2014 |
Masters | Ibanda Hood Ahmed | Dr | Makerere University | 2013 | 2014 |
Masters | Kalema Nelson | Dr | Makerere University | 2013 | 2014 |
Masters | Katagira Winceslaus | Dr | Makerere University | 2014 | 2015 |
Masters | Agnes Bwanika Naggirinya | Dr | Makerere University | 2015 | 2016 |
Masters | Rachel Beyagira | Dr | Makerere University | 2015 | 2016 |
Masters | John Mukisa | Dr | Makerere University | 2015 | 2016 |
Masters | Musisi Emmanuel | Mr | Makerere University | 2015 | 2016 |
Masters | Ahmed Ddungu | Dr | Makerere University | 2016 | 2017 |
Masters | Pastan Lusiba | Ms | Makerere University | 2016 | 2017 |
Masters | Joseph B. Baluku | Dr | Makerere University | 2017 | 2018 |
Masters | Brenda Nakafeero | Ms | Makerere University | 2017 | 2018 |
Role | Committee/board | Start Date | End Date |
---|---|---|---|
Reviewer | African Heath Sciences | ||
Reviewer | Antiretroviral Therapy | ||
Reviewer | BMC Infectious Diseases | ||
Reviewer | British Journal of Pharmaceutical Research | ||
Reviewer | Clinical Infectious Diseases | ||
Reviewer | Expert Review of Respiratory Medicine | ||
Reviewer | International Journal of STD & AIDS | ||
Reviewer | International Journal of Tuberculosis and Lung Disease | ||
Reviewer | Journal of AIDS & Clinical Research | ||
Reviewer | Journal of Acquired Immunodeficiency Syndrome | ||
Reviewer | PLoS ONE | ||
Reviewer | Scandinavian Journal of Infectious Diseases | ||
Reviewer | The Lancet Infectious Diseases | ||
Reviewer | The Lancet Global Health | ||
Reviewer | Tuberculosis Research and Treatment | ||
Reviewer | Medical Research Council | ||
Reviewer | Wellcome Trust |
Institution | Degree | Year |
---|---|---|
Makerere University, Uganda | MBChB | 1994-01-24 |
Makerere University, Uganda | Master of Medicine | 2000-10-06 |
University of Antwerp, Belgium | PhD | 2012-01-12 |
Human Immuno-deficiency Virus (HIV) Tuberculosis (TB) Lower Respiratory Tract Infections (LRTIs)