EDCTP Alumni Network

Fostering excellence and collaboration in the next generation of researchers

Call Career Development Fellowship (CDF)
Programme EDCTP2
Start Date 2020-01-01
End Date 2022-12-31
Project Code TMA2018CDF-2357
Status Active

Title

Insight into the Role of the Microbiome in Pulmonary tuberculosis in Kampala, Uganda

Host Organisation

Institution Country
Makerere University Uganda

Current Organisation

Makerere University

Current Job Title

Lecturer

Students Supervised

Type Name Title University Start Date End Date

Memberships

Role Committee/board Start Date End Date
Associate Editor BMC Infectious Diseases 2016
Associate Editor BMC Research Notes 2020

Education

Institution Degree Year
Makerere University, Uganda PhD 2015-01-14
Makerere University, Uganda Master's 2006-01-10
Makerere University, Uganda Bachelor's 1998-01-05

Areas Of Specialisation

Tuberculosis (TB) Lower Respiratory Tract Infections (LRTIs)

Grants

Publications

Authors:
Gerald Mboowa , author
Savannah Mwesigwa , author
Eric Katagirya , author
Gaone Retshabile , author
Busisiwe C. Mlotshwa , author
Lesedi Williams , author
Adeodata Kekitiinwa , author
David Kateete , author
Eddie Wampande , author
Misaki Wayengera , author
Betty Nsangi Kintu , author
Grace P. Kisitu , author
Samuel Kyobe , author
Chester W. Brown , author
Neil A. Hanchard , author
Graeme Mardon , author
Moses Joloba , author
Gabriel Anabwani , author
Ed Pettitt , author
Masego Tsimako-Johnstone , author
Ishmael Kasvosve , author
Koketso Maplanka , author
Sununguko W. Mpoloka , author
Makhosazana Hlatshwayo , author
Mogomotsi Matshaba , author
Date:
2018-06-21
Journal:
Content:
Authors:
David Kateete , author
Benon B Asiimwe , author
Raymond Mayanja , author
Brian Mujuni , author
Freddie Bwanga , author
Christine F Najjuka , author
Karin Källander , author
Elizeus Rutebemberwa , author
Date:
2019-07-03
Journal:
Content:
Authors:
George W. Kasule , author
David P. Kateete , author
Moses L. Joloba , author
Date:
2016-04-01
Journal:
BMC Infect Dis
Content:
Authors:
David P Kateete , author
Sylvia Namazzi , author
Moses Okee , author
Alfred Okeng , author
Hannington Baluku , author
Nathan L Musisi , author
Fred A Katabazi , author
Moses L Joloba , author
Robert Ssentongo , author
Florence C Najjuka , author
Date:
2011-01-01
Journal:
BMC Research Notes
Content:
Authors:
Misaki Wayengera , author
Ivan Mwebaza , author
Johnson Welishe , author
Cynthia Nakimuli , author
David P Kateete , author
Eddie Wampande , author
Samuel Kirimunda , author
Lois Bayigga , author
Carol Musubika , author
Peace Babirye , author
Benon Asiimwe , author
Moses L Joloba , author
Date:
2017-01-01
Journal:
Mycobacterial Diseases
Content:
Authors:
Christine F. Najjuka , author
David P. Kateete , author
Henry M. Kajumbula , author
Moses L. Joloba , author
Sabiha Y. Essack , author
Date:
2016-04-01
Journal:
BMC Res Notes
Content:
Authors:
W. Ssengooba , author
D. Lukoye , author
C. J. Meehan , author
D. P. Kateete , author
M. L. Joloba , author
B. C. de Jong , author
F. G. Cobelens , author
F. van Leth , author
Date:
2017-05-01
Journal:
The International Journal of Tuberculosis and Lung Disease
Content:
Authors:
Jonathan Mayito , author
Irene Andia Biraro , author
Stephen T. Reece , author
Adrian R. Martineau , author
David P. Kateete , author
Date:
2020-07-29
Journal:
Content:
Authors:
Dickson Aruhomukama , author
Christine F. Najjuka , author
Henry Kajumbula , author
Moses Okee , author
Gerald Mboowa , author
Ivan Sserwadda , author
Richard Mayanja , author
Moses L. Joloba , author
David P. Kateete , author
Date:
2019-12-01
Journal:
BMC Infectious Diseases
Content:
Authors:
Naghib Bogere , author
Felix Bongomin , author
Andrew Katende , author
Kenneth Ssebambulidde , author
Willy Ssengooba , author
Henry Ssenfuka , author
Edgar Kigozi , author
Samuel Biraro , author
David P. Kateete , author
Irene Andia-Biraro , author
Date:
2021-12-01
Journal:
International Journal of Infectious Diseases
Content:
Authors:
David P Kateete , author
Henry Kajumbula , author
Deogratias H Kaddu-Mulindwa , author
Augustine K Ssevviri , author
Date:
2012-01-01
Journal:
BMC Research Notes
Content:
Authors:
David Kateete , author
Benon B Asiimwe , author
Raymond Mayanja , author
Brian Mujuni , author
Freddie Bwanga , author
Christine F Najjuka , author
Karin Källander , author
Elizeus Rutebemberwa , author
Date:
2019-10-01
Journal:
Content:
Authors:
Bayigga, L.
Kateete, D.P.
Anderson, D.J.
Sekikubo, M.
Nakanjako, D.
Date:
2019-01-01
Journal:
American Journal of Obstetrics and Gynecology
Content:
Authors:
David Patrick Kateete , author
Benon B. Asiimwe , author
Raymond Mayanja , author
Brian Mujuni , author
Freddie Bwanga , author
Christine F. Najjuka , author
Karin Källander , author
Elizeus Rutebemberwa , author
Date:
2019-12-01
Journal:
BMC Infectious Diseases
Content:
Authors:
Jeremiah Seni , author
Christine F Najjuka , author
David P Kateete , author
Patson Makobore , author
Moses L Joloba , author
Henry Kajumbula , author
Antony Kapesa , author
Freddie Bwanga , author
Date:
2013-01-01
Journal:
BMC Research Notes
Content:
Authors:
Benon B Asiimwe , author
Moses L Joloba , author
Solomon Ghebremichael , author
Tuija Koivula , author
David P Kateete , author
Fred A Katabazi , author
Alexander Pennhag , author
Ramona Petersson , author
Gunilla Kallenius , author
Date:
2009-02-05
Journal:
BMC Infect Dis
Content:
Authors:
David Kateete , author
Benon B Asiimwe , author
Raymond Mayanja , author
Brian Mujuni , author
Freddie Bwanga , author
Christine F Najjuka , author
Karin Källander , author
Elizeus Rutebemberwa , author
Date:
2019-10-02
Journal:
Content:
Authors:
Misaki Wayengera , author
Ivan Mwebaza , author
Johnson Welishe , author
Alice Bayiyana , author
David P. Kateete , author
Eddie Wampande , author
Samuel Kirimunda , author
Edgar Kigozi , author
Fred Katabazi , author
Carol Musubika , author
Samuel Kyobe , author
Peace Babirye , author
Benon Asiimwe , author
Moses L. Joloba , author
Date:
2017-08-08
Journal:
BMC Research Notes
Content:
Authors:
Wayengera, M.
Kateete, D.P.
Asiimwe, B.
Joloba, M.L.
Date:
2018-01-01
Journal:
BMC Infectious Diseases
Content:
Authors:
David P Kateete , author
Moses Okee , author
Fred A Katabazi , author
Alfred Okeng , author
Jeniffer Asiimwe , author
Henry W Boom , author
Kathleen D Eisenach , author
Moses L Joloba , author
Date:
2010-01-01
Journal:
BMC Microbiology
Content:
Authors:
Frederick S. BUCKNER , author
David P. KATEETE , author
George W. LUBEGA , author
Wesley C. Van VOORHIS , author
Kohei YOKOYAMA , author
Date:
2002-11-01
Journal:
Biochem. J.
Content:
Authors:
Nicholas Ezati , author
Deus Lukoye , author
Eddie M Wampande , author
Kenneth Musisi , author
George W Kasule , author
Frank GJ Cobelens , author
David P Kateete , author
Moses L Joloba , author
Date:
2014-01-01
Journal:
BMC Infect Dis
Content:
Authors:
David Patrick Kateete , author
Moses S Okee , author
Moses L Joloba , author
Margaret Okello , author
Florence Christine Najjuka , author
Fred Ashaba Katabazi , author
Freddie Bwanga , author
Ann Nanteza , author
Date:
2012-03-01
Journal:
The Journal of Infection in Developing Countries
Content:
Authors:
Date:
2014-10-31
Journal:
Content:
A Thesis Submitted to the Directorate of Research and Graduate Training Makerere University, for the Award of the Degree of Doctor of Philosophy (Medical Molecular Microbiology) of Makerere University
Authors:
Date:
1999-01-01
Journal:
Avian Pathology
Content:
http://dx.doi.org/10.1080/03079459994830
Authors:
Julius Okuni , author
Chrysostomos I Dovas , author
Panayiotis Loukopoulos , author
Ilias G Bouzalas , author
David Kateete , author
Moses L Joloba , author
Lonzy Ojok , author
Date:
2012-01-01
Journal:
BMC Veterinary Research
Content:
Authors:
Christopher Muchwa , author
Joseph Akol , author
Alfred Etwom , author
Karen Morgan , author
Patrick Orikiriza , author
Francis Mumbowa , author
Paul R Odong , author
David P Kateete , author
Kathleen D Eisenach , author
Moses L Joloba , author
Date:
2012-01-01
Journal:
BMC Research Notes
Content:
Authors:
Christine F Najjuka , author
David Patrick Kateete , author
Dennis K Lodiongo , author
Obede Mambo , author
Chunderika Mocktar , author
William Kayondo , author
Hannington Baluku , author
Henry M Kajumbula , author
Sabiha Y Essack , author
Moses L Joloba , author
Date:
2020-11-30
Journal:
Content:
Authors:
Fredrick Masiga , author
Edgar Kigozi , author
Christine Florence Najjuka , author
Henry Kajumbula , author
David Kateete , author
Date:
2020-04-07
Journal:
Content:
Authors:
David Patrick Kateete , author
Fred Ashaba Katabazi , author
Alfred Okeng , author
Moses Okee , author
Conrad Musinguzi , author
Benon Byamugisha Asiimwe , author
Samuel Kyobe , author
Jeniffer Asiimwe , author
W. Henry Boom , author
Moses Lutaakome Joloba , author
Riccardo Manganelli , editor
Date:
2012-09-01
Journal:
PLoS ONE
Content:
Authors:
David Patrick Kateete , Kateete, D.P., Mbabazi, M.M., Nakazzi, F. et al. Sputum microbiota profiles of treatment-naïve TB patients in Uganda before and during first-line therapy. Sci Rep 11, 24486 (2021). https://doi.org/10.1038/s41598-021-04271-y
Date:
2021-12-29
Journal:
Scientific Reports
Content:

Information on microbiota dynamics in pulmonary tuberculosis (TB) in Africa is scarce. Here, we sequenced sputa from 120 treatment-naïve TB patients in Uganda, and investigated changes in microbiota of 30 patients with treatment-response follow-up samples. Overall, HIV-status and anti-TB treatment were associated with microbial structural and abundance changes. The predominant phyla were BacteroidetesFirmicutesProteobacteria, Fusobacteria and Actinobacteria, accounting for nearly 95% of the sputum microbiota composition; the predominant genera across time were Prevotella, Streptococcus, Veillonella, Haemophilus, Neisseria, Alloprevotella, Porphyromonas, Fusobacterium, Gemella, and Rothia. Treatment-response follow-up at month 2 was characterized by a reduction in abundance of Mycobacterium and Fretibacterium, and an increase in Ruminococcus and Peptococcus; month 5 was characterized by a reduction in Tannerella and Fusobacterium, and an increase in members of the family Neisseriaceae. The microbiota core comprised of 44 genera that were stable during treatment. Hierarchical clustering of this core’s abundance distinctly separated baseline (month 0) samples from treatment follow-up samples (months 2/5). We also observed a reduction in microbial diversity with 9.1% (CI 6–14%) of the structural variation attributed to HIV-status and anti-TB treatment. Our findings show discernible microbiota signals associated with treatment with potential to inform anti-TB treatment response monitoring.

Authors:
David P Kateete , author
Cyrus N Kimani , author
Fred A Katabazi , author
Alfred Okeng , author
Moses S Okee , author
Ann Nanteza , author
Moses L Joloba , author
Florence C Najjuka , author
Date:
2010-01-01
Journal:
Annals of Clinical Microbiology and Antimicrobials
Content:
Authors:
Gerald Mboowa , author
Savannah Mwesigwa , author
Eric Katagirya , author
Gaone Retshabile , author
Busisiwe C. Mlotshwa , author
Lesedi Williams , author
Adeodata Kekitiinwa , author
David Kateete , author
Eddie Wampande , author
Misaki Wayengera , author
Betty Nsangi Kintu , author
Grace P. Kisitu , author
Samuel Kyobe , author
Chester W. Brown , author
Neil A. Hanchard , author
Graeme Mardon , author
Moses Joloba , author
Gabriel Anabwani , author
Ed Pettitt , author
Masego Tsimako-Johnstone , author
Ishmael Kasvosve , author
Koketso Maplanka , author
Sununguko W. Mpoloka , author
Makhosazana Hlatshwayo , author
Mogomotsi Matshaba , author
Date:
2018-04-18
Journal:
AAS Open Research
Content:
Authors:
Willy Ssengooba , author
Noah Kiwanuka , author
David P. Kateete , author
Achilles Katamba , author
Moses L. Joloba , author
Yoshihiko Hoshino , editor
Date:
2012-05-01
Journal:
PLoS ONE
Content:
Authors:
Edgar Kigozi , author
Seyed Ehtesham Hasnain , editor
George W. Kasule , author
Kenneth Musisi , author
Deus Lukoye , author
Samuel Kyobe , author
Fred Ashaba Katabazi , author
Eddie M. Wampande , author
Moses L. Joloba , author
David Patrick Kateete , author
Date:
2018-05-30
Journal:
PLOS ONE
Content:
Authors:
Willy Ssengooba , author
David P. Kateete , author
Anne Wajja , author
Eric Bugumirwa , author
Gerald Mboowa , author
Carolyn Namaganda , author
Germine Nakayita , author
Maria Nassolo , author
Francis Mumbowa , author
Benon B. Asiimwe , author
James Waako , author
Suzanne Verver , author
Philippa Musoke , author
Harriet Mayanja-Kizza , author
Moses L. Joloba , author
Date:
2012-01-01
Journal:
Tuberculosis Research and Treatment
Content:
Authors:
Jeremiah Seni , author
Freddie Bwanga , author
Christine F. Najjuka , author
Patson Makobore , author
Moses Okee , author
Stephen E. Mshana , author
Benson R. Kidenya , author
Moses L. Joloba , author
David P. Kateete , author
Tara C. Smith , editor
Date:
2013-06-01
Journal:
PLoS ONE
Content:
Authors:
David Patrick Kateete , author
Monica M Mbabazi , author
Faith Nakazzi , author
Fred A Katabazi , author
Edgar Kigozi , author
Willy Ssengooba , author
Lydia Nakiyingi , author
Sharon Namiiro , author
Alphonse Okwera , author
Moses L Joloba , author
Adrian Muwonge , author
Date:
2020-04-29
Journal:
Content:
Authors:
David Patrick Kateete , author
Freddie Bwanga , author
Jeremiah Seni , author
Raymond Mayanja , author
Edgar Kigozi , author
Brian Mujuni , author
Fred K. Ashaba , author
Hannington Baluku , author
Christine F. Najjuka , author
Karin Källander , author
Elizeus Rutebemberwa , author
Benon B. Asiimwe , author
Moses L. Joloba , author
Date:
2019-12-01
Journal:
Antimicrobial Resistance & Infection Control
Content:
Authors:
David P. Kateete , author
Moses Edolu , author
Edgar Kigozi , author
Jeffrey Kisukye , author
Hannington Baluku , author
Frank Nobert Mwiine , author
Christine F. Najjuka , author
Date:
2019-12-01
Journal:
BMC Infectious Diseases
Content:
Authors:
Lydia Nabyonga , author
David P Kateete , author
Fred A Katabazi , author
Paul R Odong , author
Christopher C Whalen , author
Katherine R Dickman , author
Joloba L Moses , author
Date:
2011-01-01
Journal:
BMC Research Notes
Content:
Authors:
Okee, M.S.
Joloba, M.L.
Okello, M.
Najjuka, F.C.
Katabazi, F.A.
Bwanga, F.
Nanteza, A.
Kateete, D.P.
Date:
2012-01-01
Journal:
Journal of Infection in Developing Countries
Content:
Authors:
David Kateete , author
Benon B Asiimwe , author
Raymond Mayanja , author
Brian Mujuni , author
Freddie Bwanga , author
Christine F Najjuka , author
Karin Källander , author
Elizeus Rutebemberwa , author
Date:
2019-10-23
Journal:
Content:
Authors:
David P. Kateete , author
Ritah Nakanjako , author
Moses Okee , author
Moses L. Joloba , author
Christine F. Najjuka , author
Date:
2017-07-01
Journal:
BMC Research Notes
Content:
Authors:
G. Ackers-Johnson , author
D. Kibombo , author
B. Kusiima , author
M.L. Nsubuga , author
E. Kigozi , author
H.M. Kajumbula , author
D.P. Kateete , author
R. Walwema , author
H.L. Ackers , author
I.B. Goodhead , author
R.J. Birtles , author
C.E. James , author
Date:
2020-11-21
Journal:
Content:
Authors:
Retshabile, G.
Mlotshwa, B.C.
Williams, L.
Mwesigwa, S.
Mboowa, G.
Huang, Z.
Rustagi, N.
Swaminathan, S.
Katagirya, E.
Kyobe, S.
Wayengera, M.
Kisitu, G.P.
Kateete, D.P.
Wampande, E.M.
Maplanka, K.
Kasvosve, I.
Pettitt, E.D.
Matshaba, M.
Nsangi, B.
Marape, M.
Tsimako-Johnstone, M.
Brown, C.W.
Yu, F.
Kekitiinwa, A.
Joloba, M.
Mpoloka, S.W.
Mardon, G.
Anabwani, G.
Hanchard, N.A.
Date:
2018-01-01
Journal:
American Journal of Human Genetics
Content:
Authors:
David Patrick Kateete , author
Usuf Kabugo , author
Hannington Baluku , author
Luke Nyakarahuka , author
Samuel Kyobe , author
Moses Okee , author
Christine Florence Najjuka , author
Moses Lutaakome Joloba , author
Stephen V. Gordon , editor
Date:
2013-05-07
Journal:
PLoS ONE
Content:
Authors:
Mayito, J.
Andia, I.
Belay, M.
Jolliffe, D.A.
Kateete, D.P.
Reece, S.T.
Martineau, A.R.
Date:
2019-01-01
Journal:
Journal of Infectious Diseases
Content:
Authors:
David Patrick Kateete , author
Rogers Kamulegeya , author
Edgar Kigozi , author
Fred Ashaba Katabazi , author
Deus Lukoye , author
Sindani Ireneaus Sebit , author
Hergeye Abdi , author
Peter Arube , author
George William Kasule , author
Kenneth Musisi , author
Myalo Glen Dlamini , author
Derrick Khumalo , author
Moses L. Joloba , author
Date:
2019-12-01
Journal:
BMC Pulmonary Medicine
Content:
Authors:
Katherine R Dickman , author
Lydia Nabyonga , author
David P Kateete , author
Fred A Katabazi , author
Benon B Asiimwe , author
Harriet K Mayanja , author
Alphonse Okwera , author
Christopher Whalen , author
Moses L Joloba , author
Date:
2010-01-01
Journal:
BMC Infect Dis
Content:
Authors:
Date:
2012-01-01
Journal:
Iranian journal of parasitology
Content:
PMID: 23109963 PMCID: PMC3469173
Authors:
Lydia Nakiyingi , author
David P Kateete , author
Ponsiano Ocama , author
William Worodria , author
Joseph B Sempa , author
Benon B Asiimwe , author
Fred A Katabazi , author
Achilles Katamba , author
Laurence Huang , author
Moses L Joloba , author
Harriet Mayanja-Kizza , author
Date:
2012-01-01
Journal:
BMC Research Notes
Content:
Authors:
David P. Kateete , author
Ritah Nakanjako , author
Juliet Namugenyi , author
Joseph Erume , author
Moses L. Joloba , author
Christine F. Najjuka , author
Date:
2016-08-09
Journal:
SpringerPlus
Content:
Authors:
Kateete, D.P.
Alezuyo, C.
Nanteza, A.
Asiimwe, C.
Lubega, G.W.
Date:
2012-01-01
Journal:
Iranian Journal of Parasitology
Content:
Authors:
Julius Boniface Okuni , author
David Patrick Kateete , author
Moses Okee , author
Anna Nanteza , author
Moses Joloba , author
Lonzy Ojok , author
Date:
2017-03-01
Journal:
Irish Veterinary Journal
Content:
Authors:
D. Lukoye , author
F. A. Katabazi , author
K. Musisi , author
D. P. Kateete , author
B. B. Asiimwe , author
M. Okee , author
M. L. Joloba , author
F. G. J. Cobelens , author
Date:
2014-04-01
Journal:
Antimicrobial Agents and Chemotherapy
Content:
Authors:
David Patrick Kateete , author
Baochuan Lin , editor
Benon B. Asiimwe , author
Raymond Mayanja , author
Christine Florence Najjuka , author
Elizeus Rutebemberwa , author
Date:
2020-02-13
Journal:
PLOS ONE
Content:
Authors:
David Kateete , author
Benon B Asiimwe , author
Raymond Mayanja , author
Brian Mujuni , author
Freddie Bwanga , author
Christine F Najjuka , author
Karin Källander , author
Elizeus Rutebemberwa , author
Date:
2019-11-18
Journal:
Content:
Authors:
Date:
2009-01-01
Journal:
Content:
A dissertation submitted to the Directorate of Research and Graduate Training (Makerere University) for the award of the Degree of Master of Science in Molecular Biology of Makerere University
Authors:
Grace Nabakooza , author
David Collins Owuor , author
Zaydah R. de Laurent , author
Nicholas Owor , author
John Timothy Kayiwa , author
Daudi Jjingo , author
Charles Nyaigoti Agoti , author
David James Nokes , author
David Patrick Kateete , author
John Mulindwa Kitayimbwa , author
Simon David William Frost , author
Julius Julian Lutwama , author
Date:
2021-07-05
Journal:
Content:
Authors:
Moses L. Joloba , author
Benson R. Kidenya , author
David P. Kateete , author
Fred A. Katabazi , author
Julian K. Muwanguzi , author
Benon B. Asiimwe , author
Simon P. Alarakol , author
Jessica L. Nakavuma , author
Saralee Bajaksouzian , author
Anne Windau , author
Michael R. Jacobs , author
Date:
2010-08-01
Journal:
International Journal of Antimicrobial Agents
Content:

Projects

Send a Message